Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-Disease

Hodgkin's lymphoma is a disease with a high rate of curability under classic chemo-radiotherapy regimes. Complications due to chemotherapy could include viral reactivation due to chronic lymphopenia. BK virus (BKV) is a polyoma virus belonging to the Papovaviridae family with antibody seropreva...

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Main Authors: R. Le Calloch, J. C. Ianotto, C. Berthou, A. Tempescul
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2011/592470
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author R. Le Calloch
J. C. Ianotto
C. Berthou
A. Tempescul
author_facet R. Le Calloch
J. C. Ianotto
C. Berthou
A. Tempescul
author_sort R. Le Calloch
collection DOAJ
description Hodgkin's lymphoma is a disease with a high rate of curability under classic chemo-radiotherapy regimes. Complications due to chemotherapy could include viral reactivation due to chronic lymphopenia. BK virus (BKV) is a polyoma virus belonging to the Papovaviridae family with antibody seroprevalences in healthy populations varying from 60% to 80%. Initial infections are asymptomatic usually occur in early childhood, after which the viruses remain latent in the kidneys or urothelium. Reactivation of BKV occurs in individuals with severe immunosuppression during HIV infections, transplantation or, exceptionally, after classical chemotherapy. BKV incidence is approximately 0% to 5% in immunocompetent individuals. Reactivation is associated with nephropathy and haemorrhagic cystitis. Herein, we present a case of a haemorrhagic cystitis due to BKV reactivation in a patient with Hodgkin's disease treated with chemotherapy.
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spelling doaj-art-00b4ae9a7188494db293c9d27ae510952025-02-03T01:09:12ZengWileyCase Reports in Hematology2090-65602090-65792011-01-01201110.1155/2011/592470592470Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-DiseaseR. Le Calloch0J. C. Ianotto1C. Berthou2A. Tempescul3Department of Clinical Hematology, Institute of Cancerology and Hematology, CHU Brest, 2 avenue Foch, 29609 Brest Cedex, FranceDepartment of Clinical Hematology, Institute of Cancerology and Hematology, CHU Brest, 2 avenue Foch, 29609 Brest Cedex, FranceDepartment of Clinical Hematology, Institute of Cancerology and Hematology, CHU Brest, 2 avenue Foch, 29609 Brest Cedex, FranceDepartment of Clinical Hematology, Institute of Cancerology and Hematology, CHU Brest, 2 avenue Foch, 29609 Brest Cedex, FranceHodgkin's lymphoma is a disease with a high rate of curability under classic chemo-radiotherapy regimes. Complications due to chemotherapy could include viral reactivation due to chronic lymphopenia. BK virus (BKV) is a polyoma virus belonging to the Papovaviridae family with antibody seroprevalences in healthy populations varying from 60% to 80%. Initial infections are asymptomatic usually occur in early childhood, after which the viruses remain latent in the kidneys or urothelium. Reactivation of BKV occurs in individuals with severe immunosuppression during HIV infections, transplantation or, exceptionally, after classical chemotherapy. BKV incidence is approximately 0% to 5% in immunocompetent individuals. Reactivation is associated with nephropathy and haemorrhagic cystitis. Herein, we present a case of a haemorrhagic cystitis due to BKV reactivation in a patient with Hodgkin's disease treated with chemotherapy.http://dx.doi.org/10.1155/2011/592470
spellingShingle R. Le Calloch
J. C. Ianotto
C. Berthou
A. Tempescul
Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-Disease
Case Reports in Hematology
title Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-Disease
title_full Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-Disease
title_fullStr Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-Disease
title_full_unstemmed Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-Disease
title_short Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-Disease
title_sort hemorrhagic cystitis due to bk reactivation in a young female treated for hodgkin disease
url http://dx.doi.org/10.1155/2011/592470
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AT cberthou hemorrhagiccystitisduetobkreactivationinayoungfemaletreatedforhodgkindisease
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