Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism

Primary hyperparathyroidism (PHPT) and subsequent hypercalcemia have been reported to be associated with psychosis. Here we report the case of a 28-year-old cannabis using male with his first contact with psychiatric care because of mood instability, bizarre behavior, and poor ability to carry out a...

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Main Authors: Rachael J. Murphy, Subin Paul, Ralph Primelo
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2024/8126125
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author Rachael J. Murphy
Subin Paul
Ralph Primelo
author_facet Rachael J. Murphy
Subin Paul
Ralph Primelo
author_sort Rachael J. Murphy
collection DOAJ
description Primary hyperparathyroidism (PHPT) and subsequent hypercalcemia have been reported to be associated with psychosis. Here we report the case of a 28-year-old cannabis using male with his first contact with psychiatric care because of mood instability, bizarre behavior, and poor ability to carry out activities of daily living. Hypercalcemia was identified, and a subsequent endocrine workup confirmed PHPT. After parathyroidectomy, there was no longer any need for antipsychotic or other psychotropic medications; the report emphasizes the importance of considering organic causes, such as hyperparathyroidism, in patients presenting with psychotic-like symptoms, including in the setting of substance use disorder. Prompt recognition and appropriate management of the underlying condition are crucial for optimizing patient outcomes.
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spelling doaj-art-00a41e39ba314fc08fad71ccb9881bd42025-02-03T07:23:44ZengWileyCase Reports in Psychiatry2090-68382024-01-01202410.1155/2024/8126125Parathyroid Paranoia: Unveiling Psychosis in HyperparathyroidismRachael J. Murphy0Subin Paul1Ralph Primelo2Department of PsychiatryMorsani College of MedicineDepartment of PsychiatryPrimary hyperparathyroidism (PHPT) and subsequent hypercalcemia have been reported to be associated with psychosis. Here we report the case of a 28-year-old cannabis using male with his first contact with psychiatric care because of mood instability, bizarre behavior, and poor ability to carry out activities of daily living. Hypercalcemia was identified, and a subsequent endocrine workup confirmed PHPT. After parathyroidectomy, there was no longer any need for antipsychotic or other psychotropic medications; the report emphasizes the importance of considering organic causes, such as hyperparathyroidism, in patients presenting with psychotic-like symptoms, including in the setting of substance use disorder. Prompt recognition and appropriate management of the underlying condition are crucial for optimizing patient outcomes.http://dx.doi.org/10.1155/2024/8126125
spellingShingle Rachael J. Murphy
Subin Paul
Ralph Primelo
Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism
Case Reports in Psychiatry
title Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism
title_full Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism
title_fullStr Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism
title_full_unstemmed Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism
title_short Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism
title_sort parathyroid paranoia unveiling psychosis in hyperparathyroidism
url http://dx.doi.org/10.1155/2024/8126125
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AT subinpaul parathyroidparanoiaunveilingpsychosisinhyperparathyroidism
AT ralphprimelo parathyroidparanoiaunveilingpsychosisinhyperparathyroidism