Efficacy and safety of pseudolaric acid B against Echinococcus multilocularis in vitro and in a murine infection model

Efficacy and safety of pseudolaric acid B against Echinococcus multilocularis in vitro and in a murine infection model

IntroductionAlveolar echinococcosis (AE) is a chronic zoonotic disease caused by the larvae of the Echinococcus multilocularis (E. multilocularis). The current chemotherapy for AE relies on albendazole and mebendazole, which exhibit only parasitostatic rather than parasiticidal effects. Therefore, t...

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Bibliographic Details
Main Authors:	Zhuo-ma Dawa, Ting Zhai, Chuan-chuan Liu, Hai-ning Fan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Medicine
Subjects:	pseudolaric acid B Echinococcus multilocularis protoscolex lymphocyte matrix metalloproteinases collagen deposition
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1503472/full
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