Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian Eyes

<b>Purpose:</b> To compare the accuracy of seven artificial intelligence (AI)-based intraocular lens (IOL) power calculation formulas in medium-long Caucasian eyes regarding the root-mean-square absolute error (RMSAE), the median absolute error (MedAE) and the percentage of eyes with a p...

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Main Authors: Wiktor Stopyra, Oleksiy Voytsekhivskyy, Andrzej Grzybowski
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Life
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Online Access:https://www.mdpi.com/2075-1729/15/1/45
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author Wiktor Stopyra
Oleksiy Voytsekhivskyy
Andrzej Grzybowski
author_facet Wiktor Stopyra
Oleksiy Voytsekhivskyy
Andrzej Grzybowski
author_sort Wiktor Stopyra
collection DOAJ
description <b>Purpose:</b> To compare the accuracy of seven artificial intelligence (AI)-based intraocular lens (IOL) power calculation formulas in medium-long Caucasian eyes regarding the root-mean-square absolute error (RMSAE), the median absolute error (MedAE) and the percentage of eyes with a prediction error (PE) within ±0.5 D. <b>Methods:</b> Data on Caucasian patients who underwent uneventful phacoemulsification between May 2018 and September 2023 in MW-Med Eye Center, Krakow, Poland and Kyiv Clinical Ophthalmology Hospital Eye Microsurgery Center, Kyiv, Ukraine were reviewed. Inclusion criteria, i.e., complete biometric and refractive data, were applied. Exclusion criteria were as follows: intraoperative or postoperative complications, previous eye surgery or corneal diseases, postoperative BCVA less than 0.8, and corneal astigmatism greater than 2.0 D. Prior to phacoemulsification, IOL power was computed using SRK/T, Holladay1, Haigis, Holladay 2, and Hoffer Q. The refraction was measured three months after cataract surgery. Post-surgery intraocular lens calculations for Hill-RBF 3.0, Kane, PEARL-DGS, Ladas Super Formula AI (LSF AI), Hoffer QST, Karmona, and Nallasamy were performed. RMSAE, MedAE, and the percentage of eyes with a PE within ±0.25 D, ±0.50 D, ±0.75 D, and ±1.00 were counted. <b>Results:</b> Two hundred fourteen eyes with axial lengths ranging from 24.50 mm to 25.97 mm were tested. The Hill-RBF 3.0 formula yielded the lowest RMSAE (0.368), just before Pearl-DGS (0.374) and Hoffer QST (0.378). The lowest MedAE was achieved by Hill-RBF 3.0 (0.200), the second-lowest by LSF AI (0.210), and the third-lowest by Kane (0.228). The highest percentage of eyes with a PE within ±0.50 D was obtained by Hill-RBF 3.0, LSF AI, and Pearl-DGS (86.45%, 85.51%, and 85.05%, respectively). <b>Conclusions:</b> The Hill-RBF 3.0 formula provided highly accurate outcomes in medium-long eyes. All studied AI-based formulas yielded good results in IOL power calculation.
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spelling doaj-art-0047bbca65ac4beeab9361aa034ff8b52025-01-24T13:38:34ZengMDPI AGLife2075-17292025-01-011514510.3390/life15010045Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian EyesWiktor Stopyra0Oleksiy Voytsekhivskyy1Andrzej Grzybowski2MW-Med Eye Centre, 31-416 Krakow, PolandKyiv Clinical Ophthalmology Hospital Eye Microsurgery Center, 03680 Kyiv, UkraineInstitute for Research in Ophthalmology, Foundation for Ophthalmology Development, 61-553 Poznan, Poland<b>Purpose:</b> To compare the accuracy of seven artificial intelligence (AI)-based intraocular lens (IOL) power calculation formulas in medium-long Caucasian eyes regarding the root-mean-square absolute error (RMSAE), the median absolute error (MedAE) and the percentage of eyes with a prediction error (PE) within ±0.5 D. <b>Methods:</b> Data on Caucasian patients who underwent uneventful phacoemulsification between May 2018 and September 2023 in MW-Med Eye Center, Krakow, Poland and Kyiv Clinical Ophthalmology Hospital Eye Microsurgery Center, Kyiv, Ukraine were reviewed. Inclusion criteria, i.e., complete biometric and refractive data, were applied. Exclusion criteria were as follows: intraoperative or postoperative complications, previous eye surgery or corneal diseases, postoperative BCVA less than 0.8, and corneal astigmatism greater than 2.0 D. Prior to phacoemulsification, IOL power was computed using SRK/T, Holladay1, Haigis, Holladay 2, and Hoffer Q. The refraction was measured three months after cataract surgery. Post-surgery intraocular lens calculations for Hill-RBF 3.0, Kane, PEARL-DGS, Ladas Super Formula AI (LSF AI), Hoffer QST, Karmona, and Nallasamy were performed. RMSAE, MedAE, and the percentage of eyes with a PE within ±0.25 D, ±0.50 D, ±0.75 D, and ±1.00 were counted. <b>Results:</b> Two hundred fourteen eyes with axial lengths ranging from 24.50 mm to 25.97 mm were tested. The Hill-RBF 3.0 formula yielded the lowest RMSAE (0.368), just before Pearl-DGS (0.374) and Hoffer QST (0.378). The lowest MedAE was achieved by Hill-RBF 3.0 (0.200), the second-lowest by LSF AI (0.210), and the third-lowest by Kane (0.228). The highest percentage of eyes with a PE within ±0.50 D was obtained by Hill-RBF 3.0, LSF AI, and Pearl-DGS (86.45%, 85.51%, and 85.05%, respectively). <b>Conclusions:</b> The Hill-RBF 3.0 formula provided highly accurate outcomes in medium-long eyes. All studied AI-based formulas yielded good results in IOL power calculation.https://www.mdpi.com/2075-1729/15/1/45phacoemulsificationmedium-long eyesintraocular lensesartificial intelligenceHill-RBF formula
spellingShingle Wiktor Stopyra
Oleksiy Voytsekhivskyy
Andrzej Grzybowski
Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian Eyes
Life
phacoemulsification
medium-long eyes
intraocular lenses
artificial intelligence
Hill-RBF formula
title Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian Eyes
title_full Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian Eyes
title_fullStr Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian Eyes
title_full_unstemmed Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian Eyes
title_short Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian Eyes
title_sort prediction of seven artificial intelligence based intraocular lens power calculation formulas in medium long caucasian eyes
topic phacoemulsification
medium-long eyes
intraocular lenses
artificial intelligence
Hill-RBF formula
url https://www.mdpi.com/2075-1729/15/1/45
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AT oleksiyvoytsekhivskyy predictionofsevenartificialintelligencebasedintraocularlenspowercalculationformulasinmediumlongcaucasianeyes
AT andrzejgrzybowski predictionofsevenartificialintelligencebasedintraocularlenspowercalculationformulasinmediumlongcaucasianeyes