Neuropsychiatric Outcome of an Adolescent Who Received Deep Brain Stimulation for Tourette's Syndrome

This case study followed one adolescent patient who underwent bilateral deep brain stimulation of the centromedian parafascicular complex (CM-Pf) for debilitating, treatment refractory Tourette's syndrome for a period of 1.5 years. Neurocognitive testing showed no significant changes between ba...

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Main Authors: S. J. Pullen, C. A. Wall, K. H. Lee, S. M. Stead, B. T. Klassen, T. M. Brown
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2011/209467
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author S. J. Pullen
C. A. Wall
K. H. Lee
S. M. Stead
B. T. Klassen
T. M. Brown
author_facet S. J. Pullen
C. A. Wall
K. H. Lee
S. M. Stead
B. T. Klassen
T. M. Brown
author_sort S. J. Pullen
collection DOAJ
description This case study followed one adolescent patient who underwent bilateral deep brain stimulation of the centromedian parafascicular complex (CM-Pf) for debilitating, treatment refractory Tourette's syndrome for a period of 1.5 years. Neurocognitive testing showed no significant changes between baseline and follow-up assessments. Psychiatric assessment revealed positive outcomes in overall adaptive functioning and reduction in psychotropic medication load in this patient. Furthermore, despite significant baseline psychiatric comorbidity, this patient reported no suicidal ideation following electrode implantation. Deep brain stimulation is increasingly being used in children and adolescents. This case reports on the positive neurologic and neuropsychiatric outcome of an adolescent male with bilateral CM-Pf stimulation.
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spelling doaj-art-0046ab71fd274145b61364652073595b2025-02-03T06:01:30ZengWileyCase Reports in Neurological Medicine2090-66682090-66762011-01-01201110.1155/2011/209467209467Neuropsychiatric Outcome of an Adolescent Who Received Deep Brain Stimulation for Tourette's SyndromeS. J. Pullen0C. A. Wall1K. H. Lee2S. M. Stead3B. T. Klassen4T. M. Brown5Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USADepartment of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USADepartment of Neurologic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USADivision of Child and Adolescent Neurology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USADepartment of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USADepartment of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USAThis case study followed one adolescent patient who underwent bilateral deep brain stimulation of the centromedian parafascicular complex (CM-Pf) for debilitating, treatment refractory Tourette's syndrome for a period of 1.5 years. Neurocognitive testing showed no significant changes between baseline and follow-up assessments. Psychiatric assessment revealed positive outcomes in overall adaptive functioning and reduction in psychotropic medication load in this patient. Furthermore, despite significant baseline psychiatric comorbidity, this patient reported no suicidal ideation following electrode implantation. Deep brain stimulation is increasingly being used in children and adolescents. This case reports on the positive neurologic and neuropsychiatric outcome of an adolescent male with bilateral CM-Pf stimulation.http://dx.doi.org/10.1155/2011/209467
spellingShingle S. J. Pullen
C. A. Wall
K. H. Lee
S. M. Stead
B. T. Klassen
T. M. Brown
Neuropsychiatric Outcome of an Adolescent Who Received Deep Brain Stimulation for Tourette's Syndrome
Case Reports in Neurological Medicine
title Neuropsychiatric Outcome of an Adolescent Who Received Deep Brain Stimulation for Tourette's Syndrome
title_full Neuropsychiatric Outcome of an Adolescent Who Received Deep Brain Stimulation for Tourette's Syndrome
title_fullStr Neuropsychiatric Outcome of an Adolescent Who Received Deep Brain Stimulation for Tourette's Syndrome
title_full_unstemmed Neuropsychiatric Outcome of an Adolescent Who Received Deep Brain Stimulation for Tourette's Syndrome
title_short Neuropsychiatric Outcome of an Adolescent Who Received Deep Brain Stimulation for Tourette's Syndrome
title_sort neuropsychiatric outcome of an adolescent who received deep brain stimulation for tourette s syndrome
url http://dx.doi.org/10.1155/2011/209467
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