Neutron scattering investigations of the lipid bilayer structure pressure dependence

Lipid bilayer structure investigation results obtained with small angle neutron scattering method at the Joint Institute for Nuclear Research IBR-2M nuclear reactor (Dubna, Russia) are presented. Experiment has been per-formed with small angle neutron scattering spectrometer YuMO, upgraded with the...

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Main Authors: D. V. Soloviov, L. A. Bulavin, V. I. Gordeliy, Yu. E. Gorshkova, O. I. Ivankov, Y. S. Kovalev, A. I. Kuklin, T. Yu. Nikolaienko
Format: Article
Language:English
Published: Institute for Nuclear Research, National Academy of Sciences of Ukraine 2012-03-01
Series:Ядерна фізика та енергетика
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Online Access:http://jnpae.kinr.kiev.ua/13.1/Articles_PDF/jnpae-2012-13-0083-Soloviov.pdf
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author D. V. Soloviov
L. A. Bulavin
V. I. Gordeliy
Yu. E. Gorshkova
O. I. Ivankov
Y. S. Kovalev
A. I. Kuklin
T. Yu. Nikolaienko
author_facet D. V. Soloviov
L. A. Bulavin
V. I. Gordeliy
Yu. E. Gorshkova
O. I. Ivankov
Y. S. Kovalev
A. I. Kuklin
T. Yu. Nikolaienko
author_sort D. V. Soloviov
collection DOAJ
description Lipid bilayer structure investigation results obtained with small angle neutron scattering method at the Joint Institute for Nuclear Research IBR-2M nuclear reactor (Dubna, Russia) are presented. Experiment has been per-formed with small angle neutron scattering spectrometer YuMO, upgraded with the apparatus for performing P-V-T measurements on the substance under investigation. D2O-1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) liquid system, presenting the model of natural live membrane, has been taken as the sample for investiga-tions. The lipid bilayer spatial period was measured in experiment along with isothermal compressibility simulta-neously at different pressures. It has been shown, that the bilayer structural transition from ripple (wavelike gel-phase) phase to liquid-crystal phase is accompanied with anomalous rise of isothermal compressibility, indicat-ing occurrence of the phase transition.
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institution OA Journals
issn 1818-331X
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language English
publishDate 2012-03-01
publisher Institute for Nuclear Research, National Academy of Sciences of Ukraine
record_format Article
series Ядерна фізика та енергетика
spelling doaj-art-003fdebe262b48b99aba4c4b558ce00a2025-08-20T02:01:46ZengInstitute for Nuclear Research, National Academy of Sciences of UkraineЯдерна фізика та енергетика1818-331X2074-05652012-03-011318388Neutron scattering investigations of the lipid bilayer structure pressure dependenceD. V. Soloviov0L. A. Bulavin1V. I. Gordeliy2Yu. E. Gorshkova3O. I. Ivankov4Y. S. Kovalev5A. I. Kuklin6T. Yu. Nikolaienko7Joint Institute for Nuclear Research, Dubna, Russia; 240. Taras Shevchenko National University, Kyiv, Ukraine240. Taras Shevchenko National University, Kyiv, UkraineJoint Institute for Nuclear Research, Dubna, Russia; Institute of Structural Biology J. P. Ebel, Grenoble, France; Institute of Complex Systems, Jülich, GermanyJoint Institute for Nuclear Research, Dubna, RussiaJoint Institute for Nuclear Research, Dubna, Russia; 240. Taras Shevchenko National University, Kyiv, UkraineJoint Institute for Nuclear Research, Dubna, RussiaJoint Institute for Nuclear Research, Dubna, Russia; Bionanocenter of the Moscow Institute of Physics and Technology, Dolgoprudny, Russia240. Taras Shevchenko National University, Kyiv, UkraineLipid bilayer structure investigation results obtained with small angle neutron scattering method at the Joint Institute for Nuclear Research IBR-2M nuclear reactor (Dubna, Russia) are presented. Experiment has been per-formed with small angle neutron scattering spectrometer YuMO, upgraded with the apparatus for performing P-V-T measurements on the substance under investigation. D2O-1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) liquid system, presenting the model of natural live membrane, has been taken as the sample for investiga-tions. The lipid bilayer spatial period was measured in experiment along with isothermal compressibility simulta-neously at different pressures. It has been shown, that the bilayer structural transition from ripple (wavelike gel-phase) phase to liquid-crystal phase is accompanied with anomalous rise of isothermal compressibility, indicat-ing occurrence of the phase transition.http://jnpae.kinr.kiev.ua/13.1/Articles_PDF/jnpae-2012-13-0083-Soloviov.pdf12-dipalmitoyl-sn-glycero-3-phosphocholinesmall angle neutron scatteringP-V-T investigationsphase transi-tions
spellingShingle D. V. Soloviov
L. A. Bulavin
V. I. Gordeliy
Yu. E. Gorshkova
O. I. Ivankov
Y. S. Kovalev
A. I. Kuklin
T. Yu. Nikolaienko
Neutron scattering investigations of the lipid bilayer structure pressure dependence
Ядерна фізика та енергетика
1
2-dipalmitoyl-sn-glycero-3-phosphocholine
small angle neutron scattering
P-V-T investigations
phase transi-tions
title Neutron scattering investigations of the lipid bilayer structure pressure dependence
title_full Neutron scattering investigations of the lipid bilayer structure pressure dependence
title_fullStr Neutron scattering investigations of the lipid bilayer structure pressure dependence
title_full_unstemmed Neutron scattering investigations of the lipid bilayer structure pressure dependence
title_short Neutron scattering investigations of the lipid bilayer structure pressure dependence
title_sort neutron scattering investigations of the lipid bilayer structure pressure dependence
topic 1
2-dipalmitoyl-sn-glycero-3-phosphocholine
small angle neutron scattering
P-V-T investigations
phase transi-tions
url http://jnpae.kinr.kiev.ua/13.1/Articles_PDF/jnpae-2012-13-0083-Soloviov.pdf
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AT yuegorshkova neutronscatteringinvestigationsofthelipidbilayerstructurepressuredependence
AT oiivankov neutronscatteringinvestigationsofthelipidbilayerstructurepressuredependence
AT yskovalev neutronscatteringinvestigationsofthelipidbilayerstructurepressuredependence
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AT tyunikolaienko neutronscatteringinvestigationsofthelipidbilayerstructurepressuredependence