SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE

SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE

The article discusses the data on the functioning of Na+,K+,2Cl– cotransport – the carrier providing electroneutral symport of sodium, potassium and chloride, as well as molecular mechanisms of the regulation and physiological significance of this carrier. We analyzed the novel data on involvement o...

Full description

Saved in:
Bibliographic Details
Main Authors: S. N. Orlov, S. V. Koltsova, Ya. D. Anfinogenova, L. V. Kapilevich, S. N. Gusakova, L. V. Smagliy, M. B. Baskakov, M. A. Medvedev
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2014-12-01
Series:Бюллетень сибирской медицины
Subjects:
na+
k+
2cl– cotransport
arterial hypertension
Online Access:https://bulletin.ssmu.ru/jour/article/view/175
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The article discusses the data on the functioning of Na+,K+,2Cl– cotransport – the carrier providing electroneutral symport of sodium, potassium and chloride, as well as molecular mechanisms of the regulation and physiological significance of this carrier. We analyzed the novel data on involvement of ubiquitous isoform of Na+,K+,2Cl–cotransporter (NKCC1) in regulation of vascular smooth muscle contraction, and role of this carrier in the regulation of cell volume and intracellular chloride concentration.
ISSN:1682-0363
1819-3684

Similar Items