DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa

DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa

BackgroundHidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects hair follicles in areas with apocrine sweat glands, such as the underarms, groin, and buttocks. The pathogenesis of HS is not fully understood, but considering the key role played by the biological clock in...

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Main Authors: Uppala Radhakrishna, Uppala Ratnamala, Devendrasinh D. Jhala, Lavanya V. Uppala, Aaren Vedangi, Nazia Saiyed, Sushma R. Shah, Maulikkumar Patel, Rakesh M. Rawal, Tommaso Mazza, Gregor B. E. Jemec, Gianluigi Mazzoccoli, Giovanni Damiani
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
epigenetics
hidradenitis suppurativa
biological clock
circadian
ultradian
rhythmicity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1475424/full
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