Chronic Pulmonary Aspergillosis Complicating Bronchial Atresia

Bronchial atresia is a rare pulmonary developmental anomaly characterized by the presence of a focal obliteration of a segmental or lobar bronchial lumen. The lung distal to the atretic bronchus is typically emphysematous along with the presence of mucus filled ectatic bronchi (mucoceles). BA is usu...

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Main Authors: Mazen O. Al-Qadi, Dereddi Raja S. Reddy, Brandon T. Larsen, Vivek N. Iyer
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2014/208963
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author Mazen O. Al-Qadi
Dereddi Raja S. Reddy
Brandon T. Larsen
Vivek N. Iyer
author_facet Mazen O. Al-Qadi
Dereddi Raja S. Reddy
Brandon T. Larsen
Vivek N. Iyer
author_sort Mazen O. Al-Qadi
collection DOAJ
description Bronchial atresia is a rare pulmonary developmental anomaly characterized by the presence of a focal obliteration of a segmental or lobar bronchial lumen. The lung distal to the atretic bronchus is typically emphysematous along with the presence of mucus filled ectatic bronchi (mucoceles). BA is usually asymptomatic but pulmonary infections can rarely develop in the emphysematous lung distal to the atretic bronchus. We present a unique case of chronic pulmonary aspergillosis (CPA) in a patient with BA with no evidence of immune dysfunction. The patient was treated initially with voriconazole and subsequently underwent surgical excision of the involved area. On follow-up, she has done extremely well with no evidence for recurrence. In summary, we describe the first case of chronic pulmonary aspergillosis in an immunocompetent patient with bronchial atresia.
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institution Kabale University
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language English
publishDate 2014-01-01
publisher Wiley
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series Case Reports in Medicine
spelling doaj-art-0003fa1bf0da42cbb257c0c9e496e7462025-02-03T06:07:04ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/208963208963Chronic Pulmonary Aspergillosis Complicating Bronchial AtresiaMazen O. Al-Qadi0Dereddi Raja S. Reddy1Brandon T. Larsen2Vivek N. Iyer3Division of Pulmonary and Critical Care Medicine, Brown University, Providence, RI 02903, USADivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USADepartment of Pathology, University of Arizona Medical Center, Tucson, AZ 85724, USADivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USABronchial atresia is a rare pulmonary developmental anomaly characterized by the presence of a focal obliteration of a segmental or lobar bronchial lumen. The lung distal to the atretic bronchus is typically emphysematous along with the presence of mucus filled ectatic bronchi (mucoceles). BA is usually asymptomatic but pulmonary infections can rarely develop in the emphysematous lung distal to the atretic bronchus. We present a unique case of chronic pulmonary aspergillosis (CPA) in a patient with BA with no evidence of immune dysfunction. The patient was treated initially with voriconazole and subsequently underwent surgical excision of the involved area. On follow-up, she has done extremely well with no evidence for recurrence. In summary, we describe the first case of chronic pulmonary aspergillosis in an immunocompetent patient with bronchial atresia.http://dx.doi.org/10.1155/2014/208963
spellingShingle Mazen O. Al-Qadi
Dereddi Raja S. Reddy
Brandon T. Larsen
Vivek N. Iyer
Chronic Pulmonary Aspergillosis Complicating Bronchial Atresia
Case Reports in Medicine
title Chronic Pulmonary Aspergillosis Complicating Bronchial Atresia
title_full Chronic Pulmonary Aspergillosis Complicating Bronchial Atresia
title_fullStr Chronic Pulmonary Aspergillosis Complicating Bronchial Atresia
title_full_unstemmed Chronic Pulmonary Aspergillosis Complicating Bronchial Atresia
title_short Chronic Pulmonary Aspergillosis Complicating Bronchial Atresia
title_sort chronic pulmonary aspergillosis complicating bronchial atresia
url http://dx.doi.org/10.1155/2014/208963
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AT dereddirajasreddy chronicpulmonaryaspergillosiscomplicatingbronchialatresia
AT brandontlarsen chronicpulmonaryaspergillosiscomplicatingbronchialatresia
AT vivekniyer chronicpulmonaryaspergillosiscomplicatingbronchialatresia