Topoisomerase IIIα controls alternative lengthening of telomeres by Prashant Khandagale, Yilun Sun, Daiki Taniyama, Sourav Saha, Liton Kumar Saha, Yves Pommier

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From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica by Alessio Ottaviani, Joshua Welsch, Keli Agama, Yves Pommier, Alessandro Desideri, Bill J. Baker, Paola Fiorani

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Potent β-lactam-based tyrosyl-DNA phosphodiesterase 1 inhibitors identified by a virtual screen by Xue Zhi Zhao, Wenjie Wang, Kiall F. Suazo, Md Rasel Al Mahmud, Keli Agama, George T. Lountos, Thorkell Andresson, Yves Pommier, Terrence R. Burke

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Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair. by Kyoko Nakamura, Toshiaki Kogame, Hiroyuki Oshiumi, Akira Shinohara, Yoshiki Sumitomo, Keli Agama, Yves Pommier, Kimiko M Tsutsui, Ken Tsutsui, Edgar Hartsuiker, Tomoo Ogi, Shunichi Takeda, Yoshihito Taniguchi

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Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development. by Fumiya Moribe, Momoko Nishikori, Tsuyoshi Takashima, Daiki Taniyama, Nobuyuki Onishi, Hiroshi Arima, Hiroyuki Sasanuma, Remi Akagawa, Fathi Elloumi, Shunichi Takeda, Yves Pommier, Eiichi Morii, Akifumi Takaori-Kondo, Junko Murai

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NCI-60 whole exome sequencing and pharmacological CellMiner analyses. by William C Reinhold, Sudhir Varma, Fabricio Sousa, Margot Sunshine, Ogan D Abaan, Sean R Davis, Spencer W Reinhold, Kurt W Kohn, Joel Morris, Paul S Meltzer, James H Doroshow, Yves Pommier

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Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay. by Jiuping Ji, Yiping Zhang, Christophe E Redon, William C Reinhold, Alice P Chen, Laura K Fogli, Susan L Holbeck, Ralph E Parchment, Melinda Hollingshead, Joseph E Tomaszewski, Quentin Dudon, Yves Pommier, James H Doroshow, William M Bonner

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Development and validation of an immunoassay for quantification of topoisomerase I in solid tumor tissues. by Thomas D Pfister, Melinda Hollingshead, Robert J Kinders, Yiping Zhang, Yvonne A Evrard, Jiuping Ji, Sonny A Khin, Suzanne Borgel, Howard Stotler, John Carter, Raymond Divelbiss, Shivaani Kummar, Yves Pommier, Ralph E Parchment, Joseph E Tomaszewski, James H Doroshow

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Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition by Haojian Li, Takashi Furusawa, Renzo Cavero, Yunjie Xiao, Raj Chari, Xiaolin Wu, David Sun, Oliver Hartmann, Anjali Dhall, Ronald Holewinski, Thorkell Andresson, Baktiar Karim, Marina Villamor-Payà, Devorah Gallardo, Chi-Ping Day, Lipika R. Pal, Nishanth Ulhas Nair, Eytan Ruppin, Mirit I. Aladjem, Yves Pommier, Markus E. Diefenbacher, Jung Mi Lim, Rodney L. Levine, Travis H. Stracker, Urbain Weyemi

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ATR inhibition augments the efficacy of lurbinectedin in small‐cell lung cancer by Christopher W Schultz, Yang Zhang, Rajaa Elmeskini, Astrid Zimmermann, Haiqing Fu, Yasuhisa Murai, Darawalee Wangsa, Suresh Kumar, Nobuyuki Takahashi, Devon Atkinson, Liton Kumar Saha, Chien‐Fei Lee, Brian Elenbaas, Parth Desai, Robin Sebastian, Ajit Kumar Sharma, Melissa Abel, Brett Schroeder, Manan Krishnamurthy, Rajesh Kumar, Nitin Roper, Mirit Aladjem, Frank T Zenke, Zoe Weaver Ohler, Yves Pommier, Anish Thomas

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Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma by Nai-Yun Sun, Suresh Kumar, Yoo Sun Kim, Diana Varghese, Arnulfo Mendoza, Rosa Nguyen, Reona Okada, Karlyne Reilly, Brigitte Widemann, Yves Pommier, Fathi Elloumi, Anjali Dhall, Daiki Taniyama, Mayank Patel, Etan Aber, Cristina F. Contreras, Rosandra N. Kaplan, Katja Kiseljak-Vassiliades, Margaret E. Wierman, Dan Martinez, Jennifer Pogoriler, Amber K. Hamilton, Sharon J. Diskin, John M. Maris, Robert W. Robey, Michael M. Gottesman, Jaydira Del Rivero, Nitin Roper

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