The clinical value and most informative threshold of polygenic risk score in the Quebec City Case-Control Asthma Cohort by Martin Pariès, Stéphanie Bougeard, Aida Eslami, Zhonglin Li, Michel Laviolette, Louis-Philippe Boulet, Evelyne Vigneau, Yohan Bossé

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Context-specific eQTLs provide deeper insight into causal genes underlying shared genetic architecture of COVID-19 and idiopathic pulmonary fibrosis by Trisha Dalapati, Liuyang Wang, Angela G. Jones, Jonathan Cardwell, Iain R. Konigsberg, Yohan Bossé, Don D. Sin, Wim Timens, Ke Hao, Ivana Yang, Dennis C. Ko

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Aortic valve-specific genes dysregulated in calcific aortic valve stenosis as potential biomarkers and therapeutic targets by Pardis Zamani, Ursula Houessou, Hasanga D. Manikpurage, Zhonglin Li, Manel Dahmene, Nathalie Gaudreault, François Dagenais, Marie-Annick Clavel, Philippe Pibarot, Benoit J. Arsenault, Patrick Mathieu, Yohan Bossé, Sébastien Thériault

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Early onset multivalvular disease caused by a missense variant in lamin A/C by Alexandre Janin, Nathalie Gaudreault, Victoria Saavedra Armero, Zhonglin Li, Ran Xu, Dominique K. Boudreau, Lily Frenette, Julien Ternacle, Danielle Tardif, Sébastien Thériault, Philippe Pibarot, Patrick Mathieu, Christian Steinberg, Yohan Bossé

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A versatile and efficient method to isolate nuclei from low-input cryopreserved tissues for single-nuclei transcriptomics by Cristopher Segovia, Vincent Desrosiers, Fatemeh Khadangi, Karine Robitaille, Victoria Saavedra Armero, Myreille D’Astous, Gabriel Khelifi, Alain Bergeron, Samer Hussein, Maxime Richer, Yohan Bossé, Yves Fradet, Vincent Fradet, Steve Bilodeau

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Appraisal of multiple polygenic risk scores to estimate the risk of myocardial infarction and coronary artery lesions by Hasanga D. Manikpurage, Jérôme Bourgault, Ursula Houessou, Audrey Paulin, Pardis Zamani, Eloi Gagnon, Zhonglin Li, Dominique K. Boudreau, Aida Eslami, Pierre Voisine, Patrick Mathieu, Yohan Bossé, Benoit J. Arsenault, Sébastien Thériault

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Identification of Susceptibility Genes of Adult Asthma in French Canadian Women by Jean-Christophe Bérubé, Nathalie Gaudreault, Emilie Lavoie-Charland, Laura Sbarra, Cyndi Henry, Anne-Marie Madore, Peter D. Paré, Maarten van den Berge, David Nickle, Michel Laviolette, Catherine Laprise, Louis-Philippe Boulet, Yohan Bossé

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A Transcriptomic Approach to Sex Differences in Calcific Aortic Valve Stenosis in Patients with a Tricuspid Aortic Valve by Emma Le Nezet, MSc, Rose Tam, MSc, Zhonglin Li, MSc, Nathalie Gaudreault, BSc, Patrick Mathieu, MD, MSc, Nancy Côté, PhD, Isabelle Guisle, PhD, Sébastien Thériault, MD, MSc, Yohan Bossé, PhD, Marie-Annick Clavel, DVM, PhD

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GSTCD and INTS12 regulation and expression in the human lung. by Ma'en Obeidat, Suzanne Miller, Kelly Probert, Charlotte K Billington, Amanda P Henry, Emily Hodge, Carl P Nelson, Ceri E Stewart, Caroline Swan, Louise V Wain, María Soler Artigas, Erik Melén, Kevin Ushey, Ke Hao, Maxime Lamontagne, Yohan Bossé, Dirkje S Postma, Martin D Tobin, Ian Sayers, Ian P Hall

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Association of Forced Vital Capacity with the Developmental Gene NCOR2. by Cosetta Minelli, Charlotte H Dean, Matthew Hind, Alexessander Couto Alves, André F S Amaral, Valerie Siroux, Ville Huikari, María Soler Artigas, David M Evans, Daan W Loth, Yohan Bossé, Dirkje S Postma, Don Sin, John Thompson, Florence Demenais, John Henderson, SpiroMeta consortium, CHARGE consortium, Emmanuelle Bouzigon, Deborah Jarvis, Marjo-Riitta Järvelin, Peter Burney

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Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels. by Gian Andri Thun, Medea Imboden, Ilaria Ferrarotti, Ashish Kumar, Ma'en Obeidat, Michele Zorzetto, Margot Haun, Ivan Curjuric, Alexessander Couto Alves, Victoria E Jackson, Eva Albrecht, Janina S Ried, Alexander Teumer, Lorna M Lopez, Jennifer E Huffman, Stefan Enroth, Yohan Bossé, Ke Hao, Wim Timens, Ulf Gyllensten, Ozren Polasek, James F Wilson, Igor Rudan, Caroline Hayward, Andrew J Sandford, Ian J Deary, Beate Koch, Eva Reischl, Holger Schulz, Jennie Hui, Alan L James, Thierry Rochat, Erich W Russi, Marjo-Riitta Jarvelin, David P Strachan, Ian P Hall, Martin D Tobin, Morten Dahl, Sune Fallgaard Nielsen, Børge G Nordestgaard, Florian Kronenberg, Maurizio Luisetti, Nicole M Probst-Hensch

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Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. by Corina Lesseur, Aida Ferreiro-Iglesias, James D McKay, Yohan Bossé, Mattias Johansson, Valerie Gaborieau, Maria Teresa Landi, David C Christiani, Neil C Caporaso, Stig E Bojesen, Christopher I Amos, Sanjay Shete, Geoffrey Liu, Gadi Rennert, Demetrius Albanes, Melinda C Aldrich, Adonina Tardon, Chu Chen, Liloglou Triantafillos, John K Field, Marion Dawn Teare, Lambertus A Kiemeney, Brenda Diergaarde, Robert L Ferris, Shanbeh Zienolddiny, Stephen Lam, Andrew F Olshan, Mark C Weissler, Martin Lacko, Angela Risch, Heike Bickeböller, Andy R Ness, Steve Thomas, Loic Le Marchand, Matthew B Schabath, Victor Wünsch-Filho, Eloiza H Tajara, Angeline S Andrew, Gary M Clifford, Philip Lazarus, Kjell Grankvist, Mikael Johansson, Susanne Arnold, Olle Melander, Hans Brunnström, Stefania Boccia, Gabriella Cadoni, Wim Timens, Ma'en Obeidat, Xiangjun Xiao, Richard S Houlston, Rayjean J Hung, Paul Brennan

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Susceptibility to chronic mucus hypersecretion, a genome wide association study. by Akkelies E Dijkstra, Joanna Smolonska, Maarten van den Berge, Ciska Wijmenga, Pieter Zanen, Marjan A Luinge, Mathieu Platteel, Jan-Willem Lammers, Magnus Dahlback, Kerrie Tosh, Pieter S Hiemstra, Peter J Sterk, Avi Spira, Jorgen Vestbo, Borge G Nordestgaard, Marianne Benn, Sune F Nielsen, Morten Dahl, W Monique Verschuren, H Susan J Picavet, Henriette A Smit, Michael Owsijewitsch, Hans U Kauczor, Harry J de Koning, Eva Nizankowska-Mogilnicka, Filip Mejza, Pawel Nastalek, Cleo C van Diemen, Michael H Cho, Edwin K Silverman, James D Crapo, Terri H Beaty, David A Lomas, Per Bakke, Amund Gulsvik, Yohan Bossé, Ma'en Obeidat, Daan W Loth, Lies Lahousse, Fernando Rivadeneira, Andre G Uitterlinden, Andre Hofman, Bruno H Stricker, Guy G Brusselle, Cornelia M van Duijn, Uilke Brouwer, Gerard H Koppelman, Judith M Vonk, Martijn C Nawijn, Harry J M Groen, Wim Timens, H Marike Boezen, Dirkje S Postma, LifeLines Cohort study

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