Editorial: Digital twins in medicine—transition from theoretical concept to tool used in everyday care by Stephen Gilbert, David Drummond, Fabienne Cotte, Tjalf Ziemssen

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Neutralizing antibody titers over 12 months after SARS-CoV-2 mRNA vaccine booster in patients with relapsing multiple sclerosis continuously treated with ofatumumab by Tjalf Ziemssen, Marie Groth, Benjamin Ettle, Tobias Bopp

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Immune Response to Initial and Booster SARS-CoV-2 mRNA Vaccination in Patients Treated with Siponimod—Final Analysis of a Nonrandomized Controlled Clinical Trial (AMA-VACC) by Tjalf Ziemssen, Marie Groth, Veronika Eva Winkelmann, Tobias Bopp

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Variations in neuronal cytoskeletal integrity affect directed communication in distributed networks during inhibitory control by Julia Elmers, Moritz Mückschel, Katja Akgün, Tjalf Ziemssen, Christian Beste

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Digital Representation of Patients as Medical Digital Twins: Data-Centric Viewpoint by Stanislas Demuth, Jérôme De Sèze, Gilles Edan, Tjalf Ziemssen, Françoise Simon, Pierre-Antoine Gourraud

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Experiences of People with Multiple Sclerosis in Sensor-Based Jump Assessment by Anne Geßner, Anikó Vágó, Heidi Stölzer-Hutsch, Dirk Schriefer, Maximilian Hartmann, Katrin Trentzsch, Tjalf Ziemssen

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Extensive T-Cell Profiling Following SARS-CoV-2 mRNA Vaccination in Multiple Sclerosis Patients Treated with DMTs by Hannah Solchenberger, Marcus Odendahl, Dirk Schriefer, Undine Proschmann, Georges Katoul al Rahbani, Tjalf Ziemssen, Katja Akgün

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MS brain health quality standards: a survey on the reality in clinical practice in Germany by Isabel Voigt, Katja Akgün, Hernan Inojosa, Judith Haas, Herbert Temmes, Sven G. Meuth, Gavin Giovannoni, Tjalf Ziemssen

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CONFIDENCE treatment success: long-term real-world effectiveness and safety of ocrelizumab in Germany by Mathias Buttmann, Martin S. Weber, Martin S. Weber, Sven G. Meuth, Sandra Blümich, Stefanie Hieke-Schulz, Petra Dirks, Julius C. Eggebrecht, Tjalf Ziemssen

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Serum glial fibrillary protein reflects early brain injury dynamics and cognitive changes after deep brain stimulation surgery by Anika Frank, Jonas Arjomand, Jonas Bendig, Mia Delfs, Lisa Klingelhoefer, Witold H. Polanski, Katja Akgün, Tjalf Ziemssen, Björn Falkenburger, Nils Schnalke

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Long-term efficacy and safety of alemtuzumab in participants with highly active MS: TOPAZ clinical trial and interim analysis of TREAT-MS real-world study by Tjalf Ziemssen, Ann D. Bass, Bart Van Wijmeersch, Sara Eichau, Stephan Richter, Frank Hoffmann, Nicole M. Armstrong, Magdalena Chirieac, Janete Cunha-Santos, Barry A. Singer

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RECLAIM—A retrospective, multicenter observational study aimed at enabling the development of artificial intelligence-driven prognostic models for disease progression in multiple s... by Jelle Praet, Lina Anderhalten, Giancarlo Comi, Giancarlo Comi, Dana Horakova, Tjalf Ziemssen, Patrick Vermersch, Carsten Lukas, Koen Van Leemput, Koen Van Leemput, Koen Van Leemput, Marjan Steppe, Noemí Manero, Ella Kadas, Alexis Bernard, Jean van Rampelbergh, Erik de Boer, Vera Zingler, Dirk Smeets, Annemie Ribbens, Friedemann Paul, Friedemann Paul, Friedemann Paul, Friedemann Paul, Friedemann Paul

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