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Timothy A. Springer
Timothy A. Springer
Timothy "Tim" A. Springer
(born February 23, 1948) is an
immunologist
and the Latham Family
Professor
at
Harvard
Medical School
. He is also a professor at the Department of
Biological Chemistry
and Molecular
Pharmacology
and of the Division of
Medical Sciences
, and a Senior Investigator at the Research Program in Cellular and
Molecular Medicine
of the
Boston Children's Hospital
. Springer is best known for discovering the first
integrin
s,
LFA-1
, and
intercellular adhesion molecule
s (ICAMs), and for elucidating how these
cell adhesion molecule
s function in the
immune system
. In recent years, Springer's research interest has expanded to
malaria
,
transforming growth factor beta
(TGF-β) signaling, and
von Willebrand factor
.
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Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits
by
Yuxin Hao
,
Jiabin Yan
,
Courtney Fraser
,
Aiping Jiang
,
Murali Anuganti
,
Roushu Zhang
,
Kenneth Lloyd
,
Joseph Jardine
,
Jessica Coppola
,
Rob Meijers
,
Jing Li
,
Timothy A. Springer
Published 2024-12-01
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