Antiretroviral therapy initiated during acute infection in women with HIV-1 clade C reduces anti-Tat antibody production and lowers CD8+ T cell activation by Thandeka I. Kubheka, Kewreshini Naidoo, Kavidha Reddy, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Nompumelelo P. Mkhwanazi

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Development of a latency model for HIV-1 subtype C and the impact of long terminal repeat element genetic variation on latency reversal by Shreyal Maikoo, Robert-Jan Palstra, Krista L. Dong, Tokameh Mahmoudi, Thumbi Ndung'u, Paradise Madlala

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Genetic determinants of HIV-1 subtype C Nef-mediated SERINC3 down-regulation by Nikeisha Samlall, Tarylee Reddy, Nasreen Ismail, Mark A. Brockman, Zabrina L. Brumme, Thumbi Ndung’u, Jaclyn K. Mann

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The Confluence of HIV-1 and HIV-2: Implications for Disease Progression and Insights for Therapy by Edwin Magomere, Charles Ochieng’ Olwal, Becky Ewurama Tetteh, Mark Appeaning, Thumbi Ndung’u, George Boateng Kyei, Peter Kojo Quashie

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‘With this study, we have hope that something is coming’: community members’ perceptions of HIV cure-related research in Durban, South Africa – a qualitative focus group study... by Karine Dubé, Deli Mthimkhulu, Wiseman Ngcobo, Deborah Mindry, Luyanda Maphalala, Vanessa Pillay, Whitney Tran, Ana Korolkova, Thumbi Ndung’u, Krista Dong

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Differences in HIV-1 reservoir size, landscape characteristics, and decay dynamics in acute and chronic treated HIV-1 Clade C infection by Kavidha Reddy, Guinevere Q Lee, Nicole Reddy, Tatenda JB Chikowore, Kathy Baisley, Krista L Dong, Bruce D Walker, Xu G Yu, Mathias Lichterfeld, Thumbi Ndung'u

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HIV-1 Gag-protease-driven replicative capacity influences T-cell metabolism, cytokine induction, and viral cell-to-cell spread by Omolara O. Baiyegunhi, Kensane Mthembu, Ann-Kathrin Reuschl, Doty Ojwach, Omotayo Farinre, Murunwa Maimela, Sheila Balinda, Matt Price, Madeleine J. Bunders, Marcus Altfeld, Clare Jolly, Jaclyn Mann, Thumbi Ndung’u

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Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection. by Emily B Wong, Ngomu Akeem Akilimali, Pamla Govender, Zuri A Sullivan, Cormac Cosgrove, Mona Pillay, David M Lewinsohn, William R Bishai, Bruce D Walker, Thumbi Ndung'u, Paul Klenerman, Victoria O Kasprowicz

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Sex Differences in Antiretroviral Therapy Initiation in Pediatric HIV Infection. by Masahiko Mori, Emily Adland, Paolo Paioni, Alice Swordy, Luisa Mori, Leana Laker, Maximilian Muenchhoff, Philippa C Matthews, Gareth Tudor-Williams, Nora Lavandier, Anriette van Zyl, Jacob Hurst, Bruce D Walker, Thumbi Ndung'u, Andrew Prendergast, Philip Goulder, Pieter Jooste

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Prevalence and Characteristics of Hepatitis B Virus (HBV) Coinfection among HIV-Positive Women in South Africa and Botswana. by Philippa C Matthews, Apostolos Beloukas, Amna Malik, Jonathan M Carlson, Pieter Jooste, Anthony Ogwu, Roger Shapiro, Lynn Riddell, Fabian Chen, Graz Luzzi, Manjeetha Jaggernath, Gerald Jesuthasan, Katie Jeffery, Thumbi Ndung'u, Philip J R Goulder, Anna Maria Geretti, Paul Klenerman

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Nef-specific CD8+ T cell responses contribute to HIV-1 immune control. by Emily Adland, Jonathan M Carlson, Paolo Paioni, Henrik Kløverpris, Roger Shapiro, Anthony Ogwu, Lynn Riddell, Graz Luzzi, Fabian Chen, Thambiah Balachandran, David Heckerman, Anette Stryhn, Anne Edwards, Thumbi Ndung'u, Bruce D Walker, Søren Buus, Philip Goulder, Philippa C Matthews

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‘It is scary to pause treatment’: perspectives on HIV cure-related research and analytical treatment interruptions from women diagnosed during acute HIV in Durban, South Africa: So... by Deli Mthimkhulu, Krista L. Dong, Mzwakhe Wiseman Ngcobo, Deborah Mindry, Ayanda Zulu, Ntombifuthi Langa, Luyanda Maphalala, Vanessa Pillay, Maud Mthembu, Annie Miall, Whitney Tran, Ana Dillen, Fang Wan, Ali Ahmed, Jamila K. Stockman, Maryam Hussain, Thumbi Ndung’u, Karine Dubé

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Distinct neutralization sensitivity between adult and infant transmitted/founder HIV-1 subtype C viruses to broadly neutralizing monoclonal antibodies. by Bongiwe Ndlovu, Kamini Gounder, Nelisiwe Zikhali, Lanish Singh, Ntokozo Ntshangase, Nombali Gumede, Jane Millar, Rebecca T van Dorsten, Nicholas E Grayson, David Bonsall, Sandra E Chaudron, Jennifer Mabuka, Krista L Dong, Bruce D Walker, Penny L Moore, Philip J R Goulder, Thumbi Ndung'u

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Co-operative additive effects between HLA alleles in control of HIV-1. by Philippa C Matthews, Jennifer Listgarten, Jonathan M Carlson, Rebecca Payne, Kuan-Hsiang Gary Huang, John Frater, Dominique Goedhals, Dewald Steyn, Cloete van Vuuren, Paolo Paioni, Pieter Jooste, Anthony Ogwu, Roger Shapiro, Zenele Mncube, Thumbi Ndung'u, Bruce D Walker, David Heckerman, Philip J R Goulder

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A molecular assay for sensitive detection of pathogen-specific T-cells. by Victoria O Kasprowicz, Jessica E Mitchell, Shivan Chetty, Pamla Govender, Kuan-Hsiang Gary Huang, Helen A Fletcher, Daniel P Webster, Sebastian Brown, Anne Kasmar, Kerry Millington, Cheryl L Day, Nompumelelo Mkhwanazi, Cheryl McClurg, Fundisiwe Chonco, Ajit Lalvani, Bruce D Walker, Thumbi Ndung'u, Paul Klenerman

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Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations. by Kuan-Hsiang Gary Huang, Dominique Goedhals, Jonathan M Carlson, Mark A Brockman, Swati Mishra, Zabrina L Brumme, Stephen Hickling, Christopher S W Tang, Toshiyuki Miura, Chris Seebregts, David Heckerman, Thumbi Ndung'u, Bruce Walker, Paul Klenerman, Dewald Steyn, Philip Goulder, Rodney Phillips, Bloemfontein-Oxford Collaborative Group, Cloete van Vuuren, John Frater

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Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection. by Emily Adland, Paolo Paioni, Christina Thobakgale, Leana Laker, Luisa Mori, Maximilian Muenchhoff, Anna Csala, Margaret Clapson, Jacquie Flynn, Vas Novelli, Jacob Hurst, Vanessa Naidoo, Roger Shapiro, Kuan-Hsiang Gary Huang, John Frater, Andrew Prendergast, Julia G Prado, Thumbi Ndung'u, Bruce D Walker, Mary Carrington, Pieter Jooste, Philip J R Goulder

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Dynamics of the blood plasma proteome during hyperacute HIV-1 infection by Jamirah Nazziwa, Eva Freyhult, Mun-Gwan Hong, Emil Johansson, Filip Årman, Jonathan Hare, Kamini Gounder, Melinda Rezeli, Tirthankar Mohanty, Sven Kjellström, Anatoli Kamali, Etienne Karita, William Kilembe, Matt A. Price, Pontiano Kaleebu, Susan Allen, Eric Hunter, Thumbi Ndung’u, Jill Gilmour, Sarah L. Rowland-Jones, Eduard Sanders, Amin S. Hassan, Joakim Esbjörnsson

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An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune contro... by Vinicius A Vieira, Emily Adland, David F G Malone, Maureen P Martin, Andreas Groll, M Azim Ansari, Maria C Garcia-Guerrero, Mari C Puertas, Maximilian Muenchhoff, Claudia Fortuny Guash, Christian Brander, Javier Martinez-Picado, Alasdair Bamford, Gareth Tudor-Williams, Thumbi Ndung'u, Bruce D Walker, Veron Ramsuran, John Frater, Pieter Jooste, Dimitra Peppa, Mary Carrington, Philip J R Goulder

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Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South... by Angelique Hölzemer, Christina F Thobakgale, Camilo A Jimenez Cruz, Wilfredo F Garcia-Beltran, Jonathan M Carlson, Nienke H van Teijlingen, Jaclyn K Mann, Manjeetha Jaggernath, Seung-gu Kang, Christian Körner, Amy W Chung, Jamie L Schafer, David T Evans, Galit Alter, Bruce D Walker, Philip J Goulder, Mary Carrington, Pia Hartmann, Thomas Pertel, Ruhong Zhou, Thumbi Ndung'u, Marcus Altfeld

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