Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren’s syndrome: mTOR inhibition as a novel therapeutic strategy to halt immunopathology? by Timothy R D J Radstake, Joel A G van Roon, Maarten R Hillen, Sofie L M Blokland, Catharina G K Wichers, Maili Zimmermann, Aike A Kruize, Jasper C A Broen

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Salivary gland secretome: a novel tool towards molecular stratification of patients with primary Sjögren’s syndrome and non-autoimmune sicca by Timothy R D J Radstake, Joel A G van Roon, Maarten R Hillen, Sofie L M Blokland, Aike A Kruize, Fréderique M van Vliet-Moret, Angela Bikker, Wilco de Jager, Aridaman Pandit

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The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis. by F David Carmona, Jose-Ezequiel Martin, Lorenzo Beretta, Carmen P Simeón, Patricia E Carreira, José Luis Callejas, Mónica Fernández-Castro, Luis Sáez-Comet, Emma Beltrán, María Teresa Camps, María Victoria Egurbide, Spanish Scleroderma Group, Paolo Airó, Raffaella Scorza, Claudio Lunardi, Nicolas Hunzelmann, Gabriela Riemekasten, Torsten Witte, Alexander Kreuter, Jörg H W Distler, Rajan Madhok, Paul Shiels, Jacob M van Laar, Carmen Fonseca, Christopher Denton, Ariane Herrick, Jane Worthington, Annemie J Schuerwegh, Madelon C Vonk, Alexandre E Voskuyl, Timothy R D J Radstake, Javier Martín

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Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. by Alexandra Zhernakova, Eli A Stahl, Gosia Trynka, Soumya Raychaudhuri, Eleanora A Festen, Lude Franke, Harm-Jan Westra, Rudolf S N Fehrmann, Fina A S Kurreeman, Brian Thomson, Namrata Gupta, Jihane Romanos, Ross McManus, Anthony W Ryan, Graham Turner, Elisabeth Brouwer, Marcel D Posthumus, Elaine F Remmers, Francesca Tucci, Rene Toes, Elvira Grandone, Maria Cristina Mazzilli, Anna Rybak, Bozena Cukrowska, Marieke J H Coenen, Timothy R D J Radstake, Piet L C M van Riel, Yonghong Li, Paul I W de Bakker, Peter K Gregersen, Jane Worthington, Katherine A Siminovitch, Lars Klareskog, Tom W J Huizinga, Cisca Wijmenga, Robert M Plenge

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Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. by Olga Gorlova, Jose-Ezequiel Martin, Blanca Rueda, Bobby P C Koeleman, Jun Ying, Maria Teruel, Lina-Marcela Diaz-Gallo, Jasper C Broen, Madelon C Vonk, Carmen P Simeon, Behrooz Z Alizadeh, Marieke J H Coenen, Alexandre E Voskuyl, Annemie J Schuerwegh, Piet L C M van Riel, Marie Vanthuyne, Ruben van 't Slot, Annet Italiaander, Roel A Ophoff, Nicolas Hunzelmann, Vicente Fonollosa, Norberto Ortego-Centeno, Miguel A González-Gay, Francisco J García-Hernández, María F González-Escribano, Paolo Airo, Jacob van Laar, Jane Worthington, Roger Hesselstrand, Vanessa Smith, Filip de Keyser, Fredric Houssiau, Meng May Chee, Rajan Madhok, Paul G Shiels, Rene Westhovens, Alexander Kreuter, Elfride de Baere, Torsten Witte, Leonid Padyukov, Annika Nordin, Raffaella Scorza, Claudio Lunardi, Benedicte A Lie, Anna-Maria Hoffmann-Vold, Oyvind Palm, Paloma García de la Peña, Patricia Carreira, Spanish Scleroderma Group, John Varga, Monique Hinchcliff, Annette T Lee, Pravitt Gourh, Christopher I Amos, Frederick M Wigley, Laura K Hummers, J Lee Nelson, Gabriella Riemekasten, Ariane Herrick, Lorenzo Beretta, Carmen Fonseca, Christopher P Denton, Peter K Gregersen, Sandeep Agarwal, Shervin Assassi, Filemon K Tan, Frank C Arnett, Timothy R D J Radstake, Maureen D Mayes, Javier Martin

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Assessing the MUC5B promoter variant in a large cohort of systemic sclerosis-associated interstitial lung disease by Yannick Allanore, Marialbert Acosta-Herrera, Martin Kerick, Oliver Distler, Christopher P Denton, Alexandre E Voskuyl, Mandana Nikpour, Lorenzo Beretta, Javier Martin, Maureen D Mayes, Shervin Assassi, Ariane L Herrick, Alexander Kreuter, Nicolas Hunzelmann, P Airò, A Barton, G Riemekasten, Susanna M Proudman, F J López-Longo, E Beltrán, C Fonseca, B Fernandez-Gutierrez, A Nordin, M Freire, L Rodriguez-Rodriguez, G Major, Jeska K de Vries-Bouwstra, M A Gonzalez-Gay, G ESPINOSA, T R D J Radstake, A Gabrielli, F Diaz, V Ortiz-Santamaria, L Padyukov, G Orozco, T Witte, J Walker, W Stevens, C Lunardi, N Oreiro, José Luis Callejas, P Carreira, I Castellvi, R Ríos, R García Portales, A Fernández-Nebro, F J García-Hernández, M A Aguirre, P García de la Peña, E Vicente, J L Andreu, M Fernández de Castro, V Fonollosa, A Pros, M Rodríguez Carballeira, F J Narváez, M Rubio Rivas, A B Madroñero, B Díaz, L Trapiella, M V Egurbide, P Fanlo-Mateo, L Saez-Comet, J A Roman-Ivorra, J J Alegre Sancho, F J Blanco Garcia, C Magro, M C Vonk, R Hesselstrand, A Hoffmann-Vold, J H W Distler, J Sahhar, N Ortego-Centeno, B P C Koeleman, D Hansen, A Apostolopoulos, L Ross, G Moroncini, Alfredo Guillén-Del-Castillo, Carmen P Simeon-Aznar, Carlos Rosa-Baez, Carlos Rangel-Pelaez, Inmaculada Rodriguez-Martin, L Tío, N Ferdowsi, L V Host, G S Ngian, A Quinlivan, M Tabesh

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