Modulators of cytoskeletal reorganization in CA1 hippocampal neurons show increased expression in patients at mid-stage Alzheimer's disease. by Patricia F Kao, David A Davis, Meredith G Banigan, Charles R Vanderburg, Sudha Seshadri, Ivana Delalle

Get full text

Adherence to Life’s Essential 8 enhances gut microbiota diversity and cognitive performance by Yannick N. Wadop, Jazmyn Muhammad, Rebecca Bernal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Alexa Beiser, Alexa Beiser, Alexa Beiser, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramnik Xavier, Ramnik Xavier, Ramnik Xavier, Tiffany Kautz, Tiffany Kautz, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Bernard Fongang, Bernard Fongang, Bernard Fongang

Get full text

Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study by Nicole L. Spartano, Kendra L. Davis-Plourde, Jayandra J. Himali, Joanne M. Murabito, Ramachandran S. Vasan, Alexa S. Beiser, Sudha Seshadri

Get full text

Accelerometer‐determined physical activity and cognitive function in middle‐aged and older adults from two generations of the Framingham Heart Study by Nicole L. Spartano, Serkalem Demissie, Jayandra J. Himali, Kimberly A. Dukes, Joanne M. Murabito, Ramachandran S. Vasan, Alexa S. Beiser, Sudha Seshadri

Get full text

Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study. by Jeannette Simino, Zhiying Wang, Jan Bressler, Vincent Chouraki, Qiong Yang, Steven G Younkin, Sudha Seshadri, Myriam Fornage, Eric Boerwinkle, Thomas H Mosley

Get full text

Using family-based imputation in genome-wide association studies with large complex pedigrees: the Framingham Heart Study. by Ming-Huei Chen, Jie Huang, Wei-Min Chen, Martin G Larson, Caroline S Fox, Ramachandran S Vasan, Sudha Seshadri, Christopher J O'Donnell, Qiong Yang

Get full text

Hypothalamic Gliosis Is Associated With Multiple Cardiovascular Disease Risk Factors in the Framingham Heart Study by Justin Lo, Susan J. Melhorn, Sarah Kee, Kelsey L. W. Olerich, Alyssa Huang, Dabin Yeum, Alexa Beiser, Sudha Seshadri, Charles DeCarli, Ellen A. Schur

Get full text

514 A systematic review on sleep duration and Alzheimer’s disease fluid biomarkers: Preliminary findings by Vanessa Young, Vanessa M. Young, Joy Zeynoun, Christine Gaspard, Christopher R Frei, Jayandra Jung Himali, Antonio L. Teixeira, Tiffany Kautz, Sudha Seshadri, Andree-Ann Baril

Get full text

Long‐Term Incidence of Dementia Following Transient Ischemic Attack: A Longitudinal Cohort Study by Vasileios‐Arsenios Lioutas, Gina Peloso, Jose Rafael Romero, Hugo Aparicio, Mitzi Gonzales, Amy Werry, Dibya Himali, Jayandra Himali, Ayantika Banerjee, Saptaparni Gosh, Vasan S. Ramachandran, Alexa Beiser, Sudha Seshadri

Get full text

Short Sleep Duration and Hypertension: A Double Hit for the Brain by Stephanie Yiallourou, Andree‐Ann Baril, Crystal Wiedner, Xuemei Song, Rebecca Bernal, Dibya Himali, Marina G. Cavuoto, Charles DeCarli, Alexa Beiser, Sudha Seshadri, Jayandra J. Himali, Matthew P. Pase

Get full text

δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes. by Gyungah Jun, Juliet A Moncaster, Carolina Koutras, Sudha Seshadri, Jacqueline Buros, Ann C McKee, Georges Levesque, Philip A Wolf, Peter St George-Hyslop, Lee E Goldstein, Lindsay A Farrer

Get full text

Multi-atlas multi-modality morphometry analysis of the South Texas Alzheimer’s Disease Research Center postmortem repository by Nicolas Honnorat, Mariam Mojtabai, Karl Li, Jinqi Li, David Michael Martinez, Tanweer Rashid, Morgan Smith, Margaret E Flanagan, Elyas Fadaee, Morgan Fox Torres, Mallory Keating, Kevin Bieniek, Sudha Seshadri, Mohamad Habes

Get full text

Deep learning based detection of enlarged perivascular spaces on brain MRI by Tanweer Rashid, Hangfan Liu, Jeffrey B. Ware, Karl Li, Jose Rafael Romero, Elyas Fadaee, Ilya M. Nasrallah, Saima Hilal, R. Nick Bryan, Timothy M. Hughes, Christos Davatzikos, Lenore Launer, Sudha Seshadri, Susan R. Heckbert, Mohamad Habes

Get full text

Rapamycin treatment for Alzheimer’s disease and related dementias: a pilot phase 1 clinical trial by Mitzi M. Gonzales, Valentina R. Garbarino, Tiffany F. Kautz, Xuemei Song, Marisa Lopez-Cruzan, Leslie Linehan, Candice E. Van Skike, Gabriel A. De Erausquin, Veronica Galvan, Miranda E. Orr, Nicolas Musi, Yingxin He, Randall J. Bateman, Chen-Pin Wang, Sudha Seshadri, Ellen Kraig, Dean Kellogg

Get full text

The African Initiative for Bioinformatics Online Training in Neurodegenerative Diseases (AI‐BOND): Investing in the next generation of African neuroscientists by Bernard Fongang, Biniyam A. Ayele, Yannick N. Wadop, Emmanuel Epenge, Cyrille D. Nkouonlack, Wepnyu Y. Njamnshi, Xueqiu Jian, Murali Sargurupremraj, Alice B. S. Nono Djotsa, Paul F. Seke Etet, Rebecca Bernal, Abdon Atangana, Jose E. Cavazos, Jayandra Jung Himali, Alfred N. Fonteh, Gladys Maestre, Alfred K. Njamnshi, Sudha Seshadri

Get full text

OCT Angiography-Derived Retinal Capillary Perfusion Measures in the Framingham Heart Study by Ana D. Collazo Martinez, BS, Shu Jie Ting, MA, Anoush Shahidzadeh, MPH, Brinda Vaidya, BS, Tim Kowalczyk, MBA, Muhammed Alluwimi, PhD, Sujata Rijal, PhD, Xuejuan Jiang, PhD, Ruikang Wang, PhD, Alexa Beiser, PhD, Lucia Sobrin, MD, MPH, Sudha Seshadri, MD, DM, Amir H. Kashani, MD, PhD

Get full text

Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. by Stephen R Williams, Qiong Yang, Fang Chen, Xuan Liu, Keith L Keene, Paul Jacques, Wei-Min Chen, Galit Weinstein, Fang-Chi Hsu, Alexa Beiser, Liewei Wang, Ebony Bookman, Kimberly F Doheny, Philip A Wolf, Michelle Zilka, Jacob Selhub, Sarah Nelson, Stephanie M Gogarten, Bradford B Worrall, Sudha Seshadri, Michèle M Sale, Genomics and Randomized Trials Network, Framingham Heart Study

Get full text

Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium. by Joshua C Bis, Anita DeStefano, Xiaoming Liu, Jennifer A Brody, Seung Hoan Choi, Benjamin F J Verhaaren, Stéphanie Debette, M Arfan Ikram, Eyal Shahar, Kenneth R Butler, Rebecca F Gottesman, Donna Muzny, Christie L Kovar, Bruce M Psaty, Albert Hofman, Thomas Lumley, Mayetri Gupta, Philip A Wolf, Cornelia van Duijn, Richard A Gibbs, Thomas H Mosley, W T Longstreth, Eric Boerwinkle, Sudha Seshadri, Myriam Fornage

Get full text

Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies. by Seung Hoan Choi, Daniela Ruggiero, Rossella Sorice, Ci Song, Teresa Nutile, Albert Vernon Smith, Maria Pina Concas, Michela Traglia, Caterina Barbieri, Ndeye Coumba Ndiaye, Maria G Stathopoulou, Vasiliki Lagou, Giovanni Battista Maestrale, Cinzia Sala, Stephanie Debette, Peter Kovacs, Lars Lind, John Lamont, Peter Fitzgerald, Anke Tönjes, Vilmundur Gudnason, Daniela Toniolo, Mario Pirastu, Celine Bellenguez, Ramachandran S Vasan, Erik Ingelsson, Anne-Louise Leutenegger, Andrew D Johnson, Anita L DeStefano, Sophie Visvikis-Siest, Sudha Seshadri, Marina Ciullo

Get full text

Rethinking the residual approach: leveraging statistical learning to operationalize cognitive resilience in Alzheimer’s disease by Colin Birkenbihl, Madison Cuppels, Rory T. Boyle, Hannah M. Klinger, Oliver Langford, Gillian T. Coughlan, Michael J. Properzi, Jasmeer Chhatwal, Julie C. Price, Aaron P. Schultz, Dorene M. Rentz, Rebecca E. Amariglio, Keith A. Johnson, Rebecca F. Gottesman, Shubhabrata Mukherjee, Paul Maruff, Yen Ying Lim, Colin L. Masters, Alexa Beiser, Susan M. Resnick, Timothy M. Hughes, Samantha Burnham, Ilke Tunali, Susan Landau, Ann D. Cohen, Sterling C. Johnson, Tobey J. Betthauser, Sudha Seshadri, Samuel N. Lockhart, Sid E. O’Bryant, Prashanthi Vemuri, Reisa A. Sperling, Timothy J. Hohman, Michael C. Donohue, Rachel F. Buckley

Get full text