Aiding the discovery of new treatments for dementia by uncovering unknown benefits of existing medications by David M. Kern, M. Soledad Cepeda, Simon Lovestone, Guy R. Seabrook

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Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. by Oyinkan Sofola, Fiona Kerr, Iain Rogers, Richard Killick, Hrvoje Augustin, Carina Gandy, Marcus J Allen, John Hardy, Simon Lovestone, Linda Partridge

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Predicting progression of Alzheimer's disease using ordinal regression. by Orla M Doyle, Eric Westman, Andre F Marquand, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kłoszewska, Hilkka Soininen, Simon Lovestone, Steve C R Williams, Andrew Simmons

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A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease. by Wasim Khan, Carlos Aguilar, Steven J Kiddle, Orla Doyle, Madhav Thambisetty, Sebastian Muehlboeck, Martina Sattlecker, Stephen Newhouse, Simon Lovestone, Richard Dobson, Vincent Giampietro, Eric Westman, Andrew Simmons, Alzheimer’s Disease Neuroimaging Initiative

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Plasma biomarkers of brain atrophy in Alzheimer's disease. by Madhav Thambisetty, Andrew Simmons, Abdul Hye, James Campbell, Eric Westman, Yi Zhang, Lars-Olof Wahlund, Anna Kinsey, Mirsada Causevic, Richard Killick, Iwona Kloszewska, Patrizia Mecocci, Hilkka Soininen, Magda Tsolaki, Bruno Vellas, Christian Spenger, Simon Lovestone, AddNeuroMed Consortium

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Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis. by Petroula Proitsi, Michelle K Lupton, Latha Velayudhan, Stephen Newhouse, Isabella Fogh, Magda Tsolaki, Makrina Daniilidou, Megan Pritchard, Iwona Kloszewska, Hilkka Soininen, Patrizia Mecocci, Bruno Vellas, Alzheimer's Disease Neuroimaging Initiative, Julie Williams, GERAD1 Consortium, Robert Stewart, Pak Sham, Simon Lovestone, John F Powell

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Plasma based markers of [11C] PiB-PET brain amyloid burden. by Steven John Kiddle, Madhav Thambisetty, Andrew Simmons, Joanna Riddoch-Contreras, Abdul Hye, Eric Westman, Ian Pike, Malcolm Ward, Caroline Johnston, Michelle Katharine Lupton, Katie Lunnon, Hilkka Soininen, Iwona Kloszewska, Magda Tsolaki, Bruno Vellas, Patrizia Mecocci, Simon Lovestone, Stephen Newhouse, Richard Dobson, Alzheimers Disease Neuroimaging Initiative

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SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease. by Carlos Cruchaga, John S K Kauwe, Kevin Mayo, Noah Spiegel, Sarah Bertelsen, Petra Nowotny, Aarti R Shah, Richard Abraham, Paul Hollingworth, Denise Harold, Michael M Owen, Julie Williams, Simon Lovestone, Elaine R Peskind, Ge Li, James B Leverenz, Douglas Galasko, Alzheimer's Disease Neuroimaging Initiative, John C Morris, Anne M Fagan, David M Holtzman, Alison M Goate

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Synaptic protein CSF levels relate to memory scores in individuals without dementia by Kirsten E. J. Wesenhagen, Diederick M. de Leeuw, Jori Tomassen, Johan Gobom, Isabelle Bos, Stephanie J. B. Vos, Pablo Martinez-Lage, Mikel Tainta, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Rik Vandenberghe, Yvonne Freund-Levi, Frans Verhey, Simon Lovestone, Johannes Streffer, Valerija Dobricic, Kaj Blennow, Philip Scheltens, August B. Smit, Lars Bertram, Charlotte E. Teunissen, Henrik Zetterberg, Betty M. Tijms, Pieter Jelle Visser, the Alzheimer’s Disease Neuroimaging Initiative

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Tackling gaps in developing life‐changing treatments for dementia by Rui Mauricio, Caroline Benn, John Davis, Gerry Dawson, Lee A. Dawson, Alison Evans, Nick Fox, John Gallacher, Mike Hutton, John Isaac, Declan N.C. Jones, Lesley Jones, Giovanna Lalli, Vincenzo Libri, Simon Lovestone, Catherine Moody, Wendy Noble, Hugh Perry, James Pickett, David Reynolds, Craig Ritchie, Jonathan D. Rohrer, Carol Routledge, James Rowe, Heather Snyder, Tara Spires‐Jones, Jina Swartz, Luc Truyen, Paul Whiting, Therapeutics for Dementia Consortium

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A metabolite‐based machine learning approach to diagnose Alzheimer‐type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker d... by Daniel Stamate, Min Kim, Petroula Proitsi, Sarah Westwood, Alison Baird, Alejo Nevado‐Holgado, Abdul Hye, Isabelle Bos, Stephanie J.B. Vos, Rik Vandenberghe, Charlotte E. Teunissen, Mara Ten Kate, Philip Scheltens, Silvy Gabel, Karen Meersmans, Olivier Blin, Jill Richardson, Ellen De Roeck, Sebastiaan Engelborghs, Kristel Sleegers, Régis Bordet, Lorena Ramit, Petronella Kettunen, Magda Tsolaki, Frans Verhey, Daniel Alcolea, Alberto Lléo, Gwendoline Peyratout, Mikel Tainta, Peter Johannsen, Yvonne Freund‐Levi, Lutz Frölich, Valerija Dobricic, Giovanni B. Frisoni, José L. Molinuevo, Anders Wallin, Julius Popp, Pablo Martinez‐Lage, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Johannes Streffer, Pieter J. Visser, Simon Lovestone, Cristina Legido‐Quigley

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Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. by Lesley Jones, Peter A Holmans, Marian L Hamshere, Denise Harold, Valentina Moskvina, Dobril Ivanov, Andrew Pocklington, Richard Abraham, Paul Hollingworth, Rebecca Sims, Amy Gerrish, Jaspreet Singh Pahwa, Nicola Jones, Alexandra Stretton, Angharad R Morgan, Simon Lovestone, John Powell, Petroula Proitsi, Michelle K Lupton, Carol Brayne, David C Rubinsztein, Michael Gill, Brian Lawlor, Aoibhinn Lynch, Kevin Morgan, Kristelle S Brown, Peter A Passmore, David Craig, Bernadette McGuinness, Stephen Todd, Clive Holmes, David Mann, A David Smith, Seth Love, Patrick G Kehoe, Simon Mead, Nick Fox, Martin Rossor, John Collinge, Wolfgang Maier, Frank Jessen, Britta Schürmann, Reinhard Heun, Heike Kölsch, Hendrik van den Bussche, Isabella Heuser, Oliver Peters, Johannes Kornhuber, Jens Wiltfang, Martin Dichgans, Lutz Frölich, Harald Hampel, Michael Hüll, Dan Rujescu, Alison M Goate, John S K Kauwe, Carlos Cruchaga, Petra Nowotny, John C Morris, Kevin Mayo, Gill Livingston, Nicholas J Bass, Hugh Gurling, Andrew McQuillin, Rhian Gwilliam, Panos Deloukas, Ammar Al-Chalabi, Christopher E Shaw, Andrew B Singleton, Rita Guerreiro, Thomas W Mühleisen, Markus M Nöthen, Susanne Moebus, Karl-Heinz Jöckel, Norman Klopp, H-Erich Wichmann, Eckhard Rüther, Minerva M Carrasquillo, V Shane Pankratz, Steven G Younkin, John Hardy, Michael C O'Donovan, Michael J Owen, Julie Williams

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