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Spatially resolved analysis of TGF/BMP signalling in pancreatic ductal adenocarcinoma by digital pathology identifies patient subgroups with adverse outcome by Konstantin Bräutigam, Philipp Zens, Stefan Reinhard, Jessica L. Rohrbach, Simon J. Leedham, Anna S. Wenning, Beat Gloor, Viktor H. Koelzer, Martin Wartenberg
Published 2025-08-01Get full text
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Epithelial GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche through stromal remodelling by Eoghan J. Mulholland, Hayley L. Belnoue-Davis, Gabriel N. Valbuena, Nuray Gunduz, Amelia Ligeza, Muyang Lin, Sujata Biswas, Ester Gil Vasquez, Sulochana Omwenga, Nadia Nasreddin, Michael C. Hodder, Lai Mun Wang, Aik Seng Ng, Elizabeth Jennings, Kim S. Midwood, Neesha Dedi, Shazia Irshad, Rachel A. Ridgway, Toby J. Phesse, James East, Ian PM Tomlinson, Gareth CG Davies, Owen J. Sansom, Simon J. Leedham
Published 2025-06-01Get full text
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