Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling. by Amélie Le Bihan, Ruben de Kanter, Iñigo Angulo-Barturen, Christoph Binkert, Christoph Boss, Reto Brun, Ralf Brunner, Stephan Buchmann, Jeremy Burrows, Koen J Dechering, Michael Delves, Sonja Ewerling, Santiago Ferrer, Christoph Fischli, Francisco Javier Gamo-Benito, Nina F Gnädig, Bibia Heidmann, María Belén Jiménez-Díaz, Didier Leroy, Maria Santos Martínez, Solange Meyer, Joerg J Moehrle, Caroline L Ng, Rintis Noviyanti, Andrea Ruecker, Laura María Sanz, Robert W Sauerwein, Christian Scheurer, Sarah Schleiferboeck, Robert Sinden, Christopher Snyder, Judith Straimer, Grennady Wirjanata, Jutta Marfurt, Ric N Price, Thomas Weller, Walter Fischli, David A Fidock, Martine Clozel, Sergio Wittlin

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A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. by Stanley C Xie, Chia-Wei Tai, Craig J Morton, Liting Ma, Shih-Chung Huang, Sergio Wittlin, Yawei Du, Yongbo Hu, Con Dogovski, Mina Salimimarand, Robert Griffin, Dylan England, Elisa de la Cruz, Ioanna Deni, Tomas Yeo, Anna Y Burkhard, Josefine Striepen, Kyra A Schindler, Benigno Crespo, Francisco J Gamo, Yogesh Khandokar, Craig A Hutton, Tayla Rabie, Lyn-Marié Birkholtz, Mufuliat T Famodimu, Michael J Delves, Judith Bolsher, Karin M J Koolen, Rianne van der Laak, Anna C C Aguiar, Dhelio B Pereira, Rafael V C Guido, Darren J Creek, David A Fidock, Lawrence R Dick, Stephen L Brand, Alexandra E Gould, Steven Langston, Michael D W Griffin, Leann Tilley

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