A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal. by Pam Siggers, Gwenn-Aël Carré, Debora Bogani, Nick Warr, Sara Wells, Helen Hilton, Chris Esapa, Mohammad K Hajihosseini, Andy Greenfield

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Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1. by Nick Warr, Debora Bogani, Pam Siggers, Rachel Brixey, Hilda Tateossian, Asha Dopplapudi, Sara Wells, Michael Cheeseman, Ying Xia, Harry Ostrer, Andy Greenfield

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Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing. by Sherylanne Newton, Fanbo Kong, Adam J Carlton, Carlos Aguilar, Andrew Parker, Gemma F Codner, Lydia Teboul, Sara Wells, Steve D M Brown, Walter Marcotti, Michael R Bowl

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ENU mutagenesis reveals a novel phenotype of reduced limb strength in mice lacking fibrillin 2. by Gaynor Miller, Monica Neilan, Ruth Chia, Nabeia Gheryani, Natalie Holt, Annabelle Charbit, Sara Wells, Valter Tucci, Zuzanne Lalanne, Paul Denny, Elizabeth M C Fisher, Michael Cheeseman, Graham N Askew, T Neil Dear

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Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. by Debora Bogani, Pam Siggers, Rachel Brixey, Nick Warr, Sarah Beddow, Jessica Edwards, Debbie Williams, Dagmar Wilhelm, Peter Koopman, Richard A Flavell, Hongbo Chi, Harry Ostrer, Sara Wells, Michael Cheeseman, Andy Greenfield

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KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility. by Lee B Smith, Laura Milne, Nancy Nelson, Sharon Eddie, Pamela Brown, Nina Atanassova, Moira K O'Bryan, Liza O'Donnell, Danielle Rhodes, Sara Wells, Diane Napper, Patrick Nolan, Zuzanna Lalanne, Michael Cheeseman, Josephine Peters

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Pharmacological inhibition of FTO. by Fiona McMurray, Marina Demetriades, WeiShen Aik, Myrte Merkestein, Holger Kramer, Daniel S Andrew, Cheryl L Scudamore, Tertius A Hough, Sara Wells, Frances M Ashcroft, Michael A McDonough, Christopher J Schofield, Roger D Cox

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HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants. by Michael T Cheeseman, Hayley E Tyrer, Debbie Williams, Tertius A Hough, Paras Pathak, Maria R Romero, Helen Hilton, Sulzhan Bali, Andrew Parker, Lucie Vizor, Tom Purnell, Kate Vowell, Sara Wells, Mahmood F Bhutta, Paul K Potter, Steve D M Brown

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Adult onset global loss of the fto gene alters body composition and metabolism in the mouse. by Fiona McMurray, Chris D Church, Rachel Larder, George Nicholson, Sara Wells, Lydia Teboul, Y C Loraine Tung, Debra Rimmington, Fatima Bosch, Veronica Jimenez, Giles S H Yeo, Stephen O'Rahilly, Frances M Ashcroft, Anthony P Coll, Roger D Cox

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The Sex Inclusive Research Framework to address sex bias in preclinical research proposals by Natasha A. Karp, Manuel Berdoy, Kelly Gray, Lilian Hunt, Maggy Jennings, Angela Kerton, Matt Leach, Jordi L. Tremoleda, Jon Gledhill, Esther J. Pearl, Nathalie Percie du Sert, Benjamin Phillips, Penny S. Reynolds, Kathy Ryder, S. Clare Stanford, Sara Wells, Lucy Whitfield

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A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy. by Houman Ashrafian, Louise Docherty, Vincenzo Leo, Christopher Towlson, Monica Neilan, Violetta Steeples, Craig A Lygate, Tertius Hough, Stuart Townsend, Debbie Williams, Sara Wells, Dominic Norris, Sarah Glyn-Jones, John Land, Ivana Barbaric, Zuzanne Lalanne, Paul Denny, Dorota Szumska, Shoumo Bhattacharya, Julian L Griffin, Iain Hargreaves, Narcis Fernandez-Fuentes, Michael Cheeseman, Hugh Watkins, T Neil Dear

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Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function by Lucy A Dunbar, Pranav Patni, Carlos Aguilar, Philomena Mburu, Laura Corns, Helena RR Wells, Sedigheh Delmaghani, Andrew Parker, Stuart Johnson, Debbie Williams, Christopher T Esapa, Michelle M Simon, Lauren Chessum, Sherylanne Newton, Joanne Dorning, Prashanthini Jeyarajan, Susan Morse, Andrea Lelli, Gemma F Codner, Thibault Peineau, Suhasini R Gopal, Kumar N Alagramam, Ronna Hertzano, Didier Dulon, Sara Wells, Frances M Williams, Christine Petit, Sally J Dawson, Steve DM Brown, Walter Marcotti, Aziz El‐Amraoui, Michael R Bowl

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Applying the ARRIVE Guidelines to an In Vivo Database. by Natasha A Karp, Terry F Meehan, Hugh Morgan, Jeremy C Mason, Jeremy C Mason, Andrew Blake, Natalja Kurbatova, Damian Smedley, Julius Jacobsen, Richard F Mott, Vivek Iyer, Peter Matthews, David G Melvin, Sara Wells, Ann M Flenniken, Hiroshi Masuya, Shigeharu Wakana, Jacqueline K White, K C Kent Lloyd, Corey L Reynolds, Richard Paylor, David B West, Karen L Svenson, Elissa J Chesler, Martin Hrabě de Angelis, Glauco P Tocchini-Valentini, Tania Sorg, Yann Herault, Helen Parkinson, Ann-Marie Mallon, Steve D M Brown

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