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Optimizing CRISPR methodology for precise gene editing in the erythroid cell line BEL-A with high efficiency generation of a sickle cell anemia model by Deborah E. Daniels, Joeseph Hawksworth, Sara El Hoss, Fatima O. Oyawoye, Ivan Ferrer-Vicens, Marieangela C. Wilson, Jan Frayne
Published 2025-04-01Get full text
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Fetal‐hemoglobin‐expressing red blood cells (“F cells”) consist of three distinct types as revealed by single‐cell transcriptomic analysis of circulating reticulocytes by Helen Rooks, Cecilia Ng, Spyros Oikonomopoulos, Sara El Hoss, Charles Turner, Kar Lok Kong, Syed Mian, Yvonne Daniel, Oyesola O. Ojewunmi, John Brewin, David Rees, Ghulam J. Mufti, Jiannis Ragoussis, John Strouboulis, Stephan Menzel
Published 2025-06-01Get full text
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Reduced GATA1 levels are associated with ineffective erythropoiesis in sickle cell anemia by Sara El Hoss, Panicos Shangaris, John Brewin, Maria Eleni Psychogyiou, Cecilia Ng, Lauren Pedler, Helen Rooks, Érica M. F. Gotardo, Lucas F. S. Gushiken, Pâmela L. Brito, Kypros H Nicolaides, Nicola Conran, David C. Rees, John Strouboulis
Published 2024-12-01Get full text
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