The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population. by Nathalie Chami, Michael Preuss, Ryan W Walker, Arden Moscati, Ruth J F Loos

Get full text

Obesity-susceptibility loci and their influence on adiposity-related traits in transition from adolescence to adulthood--the HUNT study. by Koenraad Frans Cuypers, Ruth J F Loos, Kirsti Kvaløy, Bettina Kulle, Pål Romundstad, Turid Lingaas Holmen

Get full text

Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans. by Chen Liu, Huaixing Li, Lu Qi, Ruth J F Loos, Qibin Qi, Ling Lu, Wei Gan, Xu Lin

Get full text

Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population. by Qibin Qi, Huaixing Li, Ruth J F Loos, Chen Liu, Frank B Hu, Hongyu Wu, Zhijie Yu, Xu Lin

Get full text

The contribution of prenatal environment and genetic factors to the association between birth weight and adult grip strength. by Charlotte L Ridgway, Stephen J Sharp, Catherine Derom, Gaston Beunen, Robert Fagard, Robert Vlietinck, Ulf Ekelund, Ruth J F Loos

Get full text

Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study. by Shengxu Li, Jing Hua Zhao, Jian'an Luan, Ulf Ekelund, Robert N Luben, Kay-Tee Khaw, Nicholas J Wareham, Ruth J F Loos

Get full text

A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study. by Fuzhong Xue, Shengxu Li, Jian'an Luan, Zhongshang Yuan, Robert N Luben, Kay-Tee Khaw, Nicholas J Wareham, Ruth J F Loos, Jing Hua Zhao

Get full text

Modelling the Interplay between Lifestyle Factors and Genetic Predisposition on Markers of Type 2 Diabetes Mellitus Risk. by Celia G Walker, Ivonne Solis-Trapala, Christina Holzapfel, Gina L Ambrosini, Nicholas R Fuller, Ruth J F Loos, Hans Hauner, Ian D Caterson, Susan A Jebb

Get full text

Exposure to per- and poly-fluoroalkyl substances in association to later occurrence of type 2 diabetes and metabolic pathway dysregulation in a multiethnic US populationResearch in... by Vishal Midya, Meizhen Yao, Elena Colicino, Dinesh Barupal, Xiangping Lin, Chris Gennings, Leda Chatzi, Veronica Wendy Setiawan, Ruth J.F. Loos, Ryan W. Walker, Douglas I. Walker, Damaskini Valvi

Get full text

Trend in obesity prevalence in European adult cohort populations during follow-up since 1996 and their predictions to 2015. by Anne von Ruesten, Annika Steffen, Anna Floegel, Daphne L van der A, Giovanna Masala, Anne Tjønneland, Jytte Halkjaer, Domenico Palli, Nicholas J Wareham, Ruth J F Loos, Thorkild I A Sørensen, Heiner Boeing

Get full text

Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. by Cathy E Elks, Ruth J F Loos, Stephen J Sharp, Claudia Langenberg, Susan M Ring, Nicholas J Timpson, Andrew R Ness, George Davey Smith, David B Dunger, Nicholas J Wareham, Ken K Ong

Get full text

Genetic polymorphisms in the hypothalamic pathway in relation to subsequent weight change--the DiOGenes study. by Huaidong Du, Karani S Vimaleswaran, Lars Angquist, Rikke D Hansen, Daphne L van der A, Claus Holst, Anne Tjønneland, Kim Overvad, Marianne Uhre Jakobsen, Heiner Boeing, Karina Meidtner, Domenico Palli, Giovanna Masala, Nabila Bouatia-Naji, Wim H M Saris, Edith J M Feskens, Nicolas J Wareham, Thorkild I A Sørensen, Ruth J F Loos

Get full text

Dietary factors impact on the association between CTSS variants and obesity related traits. by Henri Hooton, Lars Angquist, Claus Holst, Jorg Hager, Francis Rousseau, Rikke D Hansen, Anne Tjønneland, Nina Roswall, Daphne L van der A, Kim Overvad, Marianne Uhre Jakobsen, Heiner Boeing, Karina Meidtner, Domenico Palli, Giovanna Masala, Nabila Bouatia-Naji, Wim H M Saris, Edith J M Feskens, Nicolas J Wareham, Karani S Vimaleswaran, Dominique Langin, Ruth J F Loos, Thorkild I A Sørensen, Karine Clément

Get full text

Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans. by Nora Franceschini, Cara L Carty, Yingchang Lu, Ran Tao, Yun Ju Sung, Ani Manichaikul, Jeff Haessler, Myriam Fornage, Karen Schwander, Niha Zubair, Stephanie Bien, Lucia A Hindorff, Xiuqing Guo, Suzette J Bielinski, Georg Ehret, Joel D Kaufman, Stephen S Rich, Christopher S Carlson, Erwin P Bottinger, Kari E North, D C Rao, Aravinda Chakravarti, Paula Q Barrett, Ruth J F Loos, Steven Buyske, Charles Kooperberg

Get full text

Strategies for Enriching Variant Coverage in Candidate Disease Loci on a Multiethnic Genotyping Array. by Stephanie A Bien, Genevieve L Wojcik, Niha Zubair, Christopher R Gignoux, Alicia R Martin, Jonathan M Kocarnik, Lisa W Martin, Steven Buyske, Jeffrey Haessler, Ryan W Walker, Iona Cheng, Mariaelisa Graff, Lucy Xia, Nora Franceschini, Tara Matise, Regina James, Lucia Hindorff, Loic Le Marchand, Kari E North, Christopher A Haiman, Ulrike Peters, Ruth J F Loos, Charles L Kooperberg, Carlos D Bustamante, Eimear E Kenny, Christopher S Carlson, PAGE Study

Get full text

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. by Chani J Hodonsky, Deepti Jain, Ursula M Schick, Jean V Morrison, Lisa Brown, Caitlin P McHugh, Claudia Schurmann, Diane D Chen, Yong Mei Liu, Paul L Auer, Cecilia A Laurie, Kent D Taylor, Brian L Browning, Yun Li, George Papanicolaou, Jerome I Rotter, Ryo Kurita, Yukio Nakamura, Sharon R Browning, Ruth J F Loos, Kari E North, Cathy C Laurie, Timothy A Thornton, Nathan Pankratz, Daniel E Bauer, Tamar Sofer, Alex P Reiner

Get full text

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions. by Dmitry Shungin, Wei Q Deng, Tibor V Varga, Jian'an Luan, Evelin Mihailov, Andres Metspalu, GIANT Consortium, Andrew P Morris, Nita G Forouhi, Cecilia Lindgren, Patrik K E Magnusson, Nancy L Pedersen, Göran Hallmans, Audrey Y Chu, Anne E Justice, Mariaelisa Graff, Thomas W Winkler, Lynda M Rose, Claudia Langenberg, L Adrienne Cupples, Paul M Ridker, Nicholas J Wareham, Ken K Ong, Ruth J F Loos, Daniel I Chasman, Erik Ingelsson, Tuomas O Kilpeläinen, Robert A Scott, Reedik Mägi, Guillaume Paré, Paul W Franks

Get full text

Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. by Nicole Soranzo, Fernando Rivadeneira, Usha Chinappen-Horsley, Ida Malkina, J Brent Richards, Naomi Hammond, Lisette Stolk, Alexandra Nica, Michael Inouye, Albert Hofman, Jonathan Stephens, Eleanor Wheeler, Pascal Arp, Rhian Gwilliam, P Mila Jhamai, Simon Potter, Amy Chaney, Mohammed J R Ghori, Radhi Ravindrarajah, Sergey Ermakov, Karol Estrada, Huibert A P Pols, Frances M Williams, Wendy L McArdle, Joyce B van Meurs, Ruth J F Loos, Emmanouil T Dermitzakis, Kourosh R Ahmadi, Deborah J Hart, Willem H Ouwehand, Nicholas J Wareham, Inês Barroso, Manjinder S Sandhu, David P Strachan, Gregory Livshits, Timothy D Spector, André G Uitterlinden, Panos Deloukas

Get full text

The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) St... by Lindsay Fernández-Rhodes, Jennifer R Malinowski, Yujie Wang, Ran Tao, Nathan Pankratz, Janina M Jeff, Sachiko Yoneyama, Cara L Carty, V Wendy Setiawan, Loic Le Marchand, Christopher Haiman, Steven Corbett, Ellen Demerath, Gerardo Heiss, Myron Gross, Petra Buzkova, Dana C Crawford, Steven C Hunt, D C Rao, Karen Schwander, Aravinda Chakravarti, Omri Gottesman, Noura S Abul-Husn, Erwin P Bottinger, Ruth J F Loos, Leslie J Raffel, Jie Yao, Xiuqing Guo, Suzette J Bielinski, Jerome I Rotter, Dhananjay Vaidya, Yii-Der Ida Chen, Sheila F Castañeda, Martha Daviglus, Robert Kaplan, Gregory A Talavera, Kelli K Ryckman, Ulrike Peters, Jose Luis Ambite, Steven Buyske, Lucia Hindorff, Charles Kooperberg, Tara Matise, Nora Franceschini, Kari E North

Get full text

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. by Benjamin F Voight, Hyun Min Kang, Jun Ding, Cameron D Palmer, Carlo Sidore, Peter S Chines, Noël P Burtt, Christian Fuchsberger, Yanming Li, Jeanette Erdmann, Timothy M Frayling, Iris M Heid, Anne U Jackson, Toby Johnson, Tuomas O Kilpeläinen, Cecilia M Lindgren, Andrew P Morris, Inga Prokopenko, Joshua C Randall, Richa Saxena, Nicole Soranzo, Elizabeth K Speliotes, Tanya M Teslovich, Eleanor Wheeler, Jared Maguire, Melissa Parkin, Simon Potter, N William Rayner, Neil Robertson, Kathleen Stirrups, Wendy Winckler, Serena Sanna, Antonella Mulas, Ramaiah Nagaraja, Francesco Cucca, Inês Barroso, Panos Deloukas, Ruth J F Loos, Sekar Kathiresan, Patricia B Munroe, Christopher Newton-Cheh, Arne Pfeufer, Nilesh J Samani, Heribert Schunkert, Joel N Hirschhorn, David Altshuler, Mark I McCarthy, Gonçalo R Abecasis, Michael Boehnke

Get full text