Evaluating offspring Genomic and Epigenomic alterations after prenatal exposure to Cancer treatment In Pregnancy (GE-CIP): a multicentric observational study by Lode Godderis, Bernard Thienpont, Koenraad Devriendt, Frédéric Amant, Vera Wolters, Liesbeth Lenaerts, Kristel Van Calsteren, Thierry Voet, Ilana Struys, Carolina Velázquez, Heidi Segers, Ruben van Boxtel

Get full text

Genome‐wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling by Astrid Eijkelenboom, Michal Mokry, Elzo de Wit, Lydia M Smits, Paulien E Polderman, Miranda H van Triest, Ruben van Boxtel, Almut Schulze, Wouter de Laat, Edwin Cuppen, Boudewijn M T Burgering

Get full text

Direct detection of 8-oxo-dG using nanopore sequencing by Marc Pagès-Gallego, Daan M. K. van Soest, Nicolle J. M. Besselink, Roy Straver, Janneke P. Keijer, Carlo Vermeulen, Alessio Marcozzi, Markus J. van Roosmalen, Ruben van Boxtel, Boudewijn M. T. Burgering, Tobias B. Dansen, Jeroen de Ridder

Get full text

Unraveling mutagenic processes influencing the tumor mutational patterns of individuals with constitutional mismatch repair deficiency by Dilys D. Weijers, Snežana Hinić, Emma Kroeze, Mark AJ Gorris, Gerty Schreibelt, Sjors Middelkamp, Arjen R. Mensenkamp, Reno Bladergroen, Kiek Verrijp, Nicoline Hoogerbrugge, Pieter Wesseling, Rachel S. van der Post, Jan LC Loeffen, Corrie EM Gidding, Mariëtte CA van Kouwen, I. Jolanda M. de Vries, Ruben van Boxtel, Richarda M. de Voer, Marjolijn CJ Jongmans, Roland P. Kuiper

Get full text

Small round cell sarcoma tumoroid biobank reveals CIC::DUX4 sarcoma vulnerability to MCL-1 inhibition by Femke C. A. S. Ringnalda, Gijs J. F. van Son, Laurens H. G. Verweij, Seok-Young Kim, Vicky Amo-Addae, Uta E. Flucke, Laura S. Hiemcke–Jiwa, Karin P. S. Langenberg, Jos A. M. Bramer, Lotte Heimans, Michiel A. J. van de Sande, Winan J. van Houdt, Max M. van Noesel, Hinri H. D. Kerstens, Marcel Santoso, Georg Seifert, Olivier Delattre, Katia Scotlandi, Birgit Geoerger, Johannes H. M. Merks, Jan J. Molenaar, Ruben van Boxtel, Marc van de Wetering, Karin Sanders, Hans Clevers

Get full text

Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes by Michael T Meister, Marian J A Groot Koerkamp, Terezinha de Souza, Willemijn B Breunis, Ewa Frazer‐Mendelewska, Mariël Brok, Jeff DeMartino, Freek Manders, Camilla Calandrini, Hinri H D Kerstens, Alex Janse, M Emmy M Dolman, Selma Eising, Karin P S Langenberg, Marc van Tuil, Rutger R G Knops, Sheila Terwisscha van Scheltinga, Laura S Hiemcke‐Jiwa, Uta Flucke, Johannes H M Merks, Max M van Noesel, Bastiaan B J Tops, Jayne Y Hehir‐Kwa, Patrick Kemmeren, Jan J Molenaar, Marc van de Wetering, Ruben van Boxtel, Jarno Drost, Frank C P Holstege

Get full text