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A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms. by Praveen K Vayalil, Joo-Yeun Oh, Fen Zhou, Anne R Diers, M Ryan Smith, Hafez Golzarian, Patsy G Oliver, Robin A J Smith, Michael P Murphy, Sadanandan E Velu, Aimee Landar
Published 2015-01-01Get full text
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Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism. by Rida Mourtada, Sonali B Fonseca, Simon P Wisnovsky, Mark P Pereira, Xiaoming Wang, Rose Hurren, Jeremy Parfitt, Lesley Larsen, Robin A J Smith, Michael P Murphy, Aaron D Schimmer, Shana O Kelley
Published 2013-01-01Get full text
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