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HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications. by Lishomwa C Ndhlovu, Fabio E Leal, Aaron M Hasenkrug, Aashish R Jha, Karina I Carvalho, Ijeoma G Eccles-James, Fernanda R Bruno, Raphaella G S Vieira, Vanessa A York, Glen M Chew, R Brad Jones, Yuetsu Tanaka, Walter K Neto, Sabri S Sanabani, Mario A Ostrowski, Aluisio C Segurado, Douglas F Nixon, Esper G Kallas
Published 2011-04-01Get full text
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Autologous HIV-specific T cell therapy targeting conserved epitopes is well-tolerated in six adults with HIV: an open-label, single-arm phase 1 study by Danielle K. Sohai, Michael D. Keller, Patrick J. Hanley, Fahmida Hoq, Divyesh Kukadiya, Anushree Datar, Emily Reynolds, Dennis C. Copertino, Christopher Lazarski, Chase D. McCann, Jay Tanna, Abeer Shibli, Haili Lang, Anqing Zhang, Pamela A. Chansky, Cecilia Motta, Tan T. Huynh, Bridget Dwyer, Andrew Wilson, Rebecca Lynch, Talia M. Mota, Winiffer D. Conce Alberto, Zabrina L. Brumme, Natalie N. Kinloch, Conrad Russell Y. Cruz, Lynsay MacLaren Ehui, Sarah Henn, R. Brad Jones, Catherine M. Bollard
Published 2025-05-01Get full text
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EZH2 inhibition mitigates HIV immune evasion, reduces reservoir formation, and promotes skewing of CD8+ T cells toward less-exhausted phenotypes by Andrea Gramatica, Itzayana G. Miller, Adam R. Ward, Farzana Khan, Tyler J. Kemmer, Jared Weiler, Tan Thinh Huynh, Paul Zumbo, Andrew P. Kurland, Louise Leyre, Yanqin Ren, Thais Klevorn, Dennis C. Copertino, Uchenna Chukwukere, Callie Levinger, Thomas R. Dilling, Noemi Linden, Nathan L. Board, Emma Falling Iversen, Sandra Terry, Talia M. Mota, Seden Bedir, Kiera L. Clayton, Alberto Bosque, Lynsay MacLaren Ehui, Colin Kovacs, Doron Betel, Jeffry R. Johnson, Mirko Paiardini, Ali Danesh, R. Brad Jones
Published 2025-05-01Get full text
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