Re-ranking sequencing variants in the post-GWAS era for accurate causal variant identification. by Laura L Faye, Mitchell J Machiela, Peter Kraft, Shelley B Bull, Lei Sun

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Leveraging expression from multiple tissues using sparse canonical correlation analysis and aggregate tests improves the power of transcriptome-wide association studies. by Helian Feng, Nicholas Mancuso, Alexander Gusev, Arunabha Majumdar, Megan Major, Bogdan Pasaniuc, Peter Kraft

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Genetic predisposition to higher body mass index or type 2 diabetes and leukocyte telomere length in the Nurses' Health Study. by Mengmeng Du, Jennifer Prescott, Marilyn C Cornelis, Susan E Hankinson, Edward Giovannucci, Peter Kraft, Immaculata De Vivo

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Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures by Yon Ho Jee, Ying Wang, Keum Ji Jung, Ji-Young Lee, Heejin Kimm, Rui Duan, Alkes L. Price, Alicia R. Martin, Peter Kraft

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Hypercholesterolemia induced cerebral small vessel disease. by Peter Kraft, Michael K Schuhmann, Cornelia Garz, Solveig Jandke, Daniela Urlaub, Stine Mencl, Alma Zernecke, Hans-Jochen Heinze, Roxana O Carare, Christoph Kleinschnitz, Stefanie Schreiber

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Genome-Wide Association Studies of Multiple Keratinocyte Cancers. by Luba M Pardo, Wen-Qing Li, Shih-Jen Hwang, Joris A C Verkouteren, Albert Hofman, André G Uitterlinden, Peter Kraft, Constance Turman, Jiali Han, Eunyoung Cho, Joanne M Murabito, Daniel Levy, Abrar A Qureshi, Tamar Nijsten

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Identifying chronic obstructive pulmonary disease subtypes using multi-trait geneticsResearch in context by Andrey Ziyatdinov, Brian D. Hobbs, Samir Kanaan-Izquierdo, Matthew Moll, Phuwanat Sakornsakolpat, Nick Shrine, Jing Chen, Kijoung Song, Russell P. Bowler, Peter J. Castaldi, Martin D. Tobin, Peter Kraft, Edwin K. Silverman, Hanna Julienne, Michael H. Cho, Hugues Aschard

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Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women. by Jennifer Prescott, Deborah J Thompson, Peter Kraft, Stephen J Chanock, Tina Audley, Judith Brown, Jean Leyland, Elizabeth Folkerd, Deborah Doody, Susan E Hankinson, David J Hunter, Kevin B Jacobs, Mitch Dowsett, David G Cox, Douglas F Easton, Immaculata De Vivo

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Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma by Santiago Diaz-Torres, Weixiong He, Regina Yu, IGGC International Glaucoma Genetics Consortium, Anthony P. Khawaja, Christopher J. Hammond, Pirro G. Hysi, Louis R. Pasquale, Yeda Wu, Michiaki Kubo, Masato Akiyama, Tin Aung, Ching-Yu Cheng, Chiea Chuen Khor, Peter Kraft, Jae H. Kang, Alex W. Hewitt, David A. Mackey, Jamie E. Craig, Janey L. Wiggs, Jue-Sheng Ong, Stuart MacGregor, Puya Gharahkhani

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Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses. by Nikhil K Khankari, Xiao-Ou Shu, Wanqing Wen, Peter Kraft, Sara Lindström, Ulrike Peters, Joellen Schildkraut, Fredrick Schumacher, Paolo Bofetta, Angela Risch, Heike Bickeböller, Christopher I Amos, Douglas Easton, Rosalind A Eeles, Rosalind A Eeles, Stephen B Gruber, Christopher A Haiman, David J Hunter, Stephen J Chanock, Brandon L Pierce, Wei Zheng, Colorectal Transdisciplinary Study (CORECT), Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE), Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE), Transdisciplinary Research in Cancer of the Lung (TRICL)

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Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption. by Marilyn C Cornelis, Keri L Monda, Kai Yu, Nina Paynter, Elizabeth M Azzato, Siiri N Bennett, Sonja I Berndt, Eric Boerwinkle, Stephen Chanock, Nilanjan Chatterjee, David Couper, Gary Curhan, Gerardo Heiss, Frank B Hu, David J Hunter, Kevin Jacobs, Majken K Jensen, Peter Kraft, Maria Teresa Landi, Jennifer A Nettleton, Mark P Purdue, Preetha Rajaraman, Eric B Rimm, Lynda M Rose, Nathaniel Rothman, Debra Silverman, Rachael Stolzenberg-Solomon, Amy Subar, Meredith Yeager, Daniel I Chasman, Rob M van Dam, Neil E Caporaso

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A genome-wide "pleiotropy scan" does not identify new susceptibility loci for estrogen receptor negative breast cancer. by Daniele Campa, Myrto Barrdahl, Konstantinos K Tsilidis, Gianluca Severi, W Ryan Diver, Afshan Siddiq, Stephen Chanock, Robert N Hoover, Regina G Ziegler, Christine D Berg, Saundra S Buys, Christopher A Haiman, Brian E Henderson, Fredrick R Schumacher, Loïc Le Marchand, Dieter Flesch-Janys, Sara Lindström, David J Hunter, Susan E Hankinson, Walter C Willett, Peter Kraft, David G Cox, Kay-Tee Khaw, Anne Tjønneland, Laure Dossus, Dimitrios Trichopoulos, Salvatore Panico, Carla H van Gils, Elisabete Weiderpass, Aurelio Barricarte, Malin Sund, Mia M Gaudet, Graham Giles, Melissa Southey, Laura Baglietto, Jenny Chang-Claude, Rudolf Kaaks, Federico Canzian

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Informed conditioning on clinical covariates increases power in case-control association studies. by Noah Zaitlen, Sara Lindström, Bogdan Pasaniuc, Marilyn Cornelis, Giulio Genovese, Samuela Pollack, Anne Barton, Heike Bickeböller, Donald W Bowden, Steve Eyre, Barry I Freedman, David J Friedman, John K Field, Leif Groop, Aage Haugen, Joachim Heinrich, Brian E Henderson, Pamela J Hicks, Lynne J Hocking, Laurence N Kolonel, Maria Teresa Landi, Carl D Langefeld, Loic Le Marchand, Michael Meister, Ann W Morgan, Olaide Y Raji, Angela Risch, Albert Rosenberger, David Scherf, Sophia Steer, Martin Walshaw, Kevin M Waters, Anthony G Wilson, Paul Wordsworth, Shanbeh Zienolddiny, Eric Tchetgen Tchetgen, Christopher Haiman, David J Hunter, Robert M Plenge, Jane Worthington, David C Christiani, Debra A Schaumberg, Daniel I Chasman, David Altshuler, Benjamin Voight, Peter Kraft, Nick Patterson, Alkes L Price

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Development and validation of a risk prediction model for premenopausal breast cancer in 19 cohorts by Kristen D. Brantley, Michael E. Jones, Rulla M. Tamimi, Bernard A. Rosner, Peter Kraft, Hazel B. Nichols, Katie M. O’Brien, Hans-Olov Adami, Amaia Aizpurua, Amy Berrington de González, William J. Blot, Tonje Braaten, Yu Chen, Jessica Clague DeHart, Laure Dossus, Sjoerd Elias, Renée T. Fortner, Montserrat Garcia-Closas, Inger T. Gram, Niclas Håkansson, Susan E. Hankinson, Cari M. Kitahara, Woon-Puay Koh, Martha S. Linet, Robert J. MacInnis, Giovanna Masala, Lene Mellemkjær, Roger L. Milne, David C. Muller, Hannah Lui Park, Kathryn J. Ruddy, Sven Sandin, Xiao-Ou Shu, Sandar Tin Tin, Thérèse Truong, Celine M. Vachon, Lars J. Vatten, Kala Visvanathan, Elisabete Weiderpass, Walter Willett, Alicja Wolk, Jian-Min Yuan, Wei Zheng, Dale P. Sandler, Minouk J. Schoemaker, Anthony J. Swerdlow, A. Heather Eliassen

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Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. by Karani S Vimaleswaran, Diane J Berry, Chen Lu, Emmi Tikkanen, Stefan Pilz, Linda T Hiraki, Jason D Cooper, Zari Dastani, Rui Li, Denise K Houston, Andrew R Wood, Karl Michaëlsson, Liesbeth Vandenput, Lina Zgaga, Laura M Yerges-Armstrong, Mark I McCarthy, Josée Dupuis, Marika Kaakinen, Marcus E Kleber, Karen Jameson, Nigel Arden, Olli Raitakari, Jorma Viikari, Kurt K Lohman, Luigi Ferrucci, Håkan Melhus, Erik Ingelsson, Liisa Byberg, Lars Lind, Mattias Lorentzon, Veikko Salomaa, Harry Campbell, Malcolm Dunlop, Braxton D Mitchell, Karl-Heinz Herzig, Anneli Pouta, Anna-Liisa Hartikainen, Genetic Investigation of Anthropometric Traits-GIANT Consortium, Elizabeth A Streeten, Evropi Theodoratou, Antti Jula, Nicholas J Wareham, Claes Ohlsson, Timothy M Frayling, Stephen B Kritchevsky, Timothy D Spector, J Brent Richards, Terho Lehtimäki, Willem H Ouwehand, Peter Kraft, Cyrus Cooper, Winfried März, Chris Power, Ruth J F Loos, Thomas J Wang, Marjo-Riitta Järvelin, John C Whittaker, Aroon D Hingorani, Elina Hyppönen

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Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study. by Robert Carreras-Torres, Mattias Johansson, Philip C Haycock, Kaitlin H Wade, Caroline L Relton, Richard M Martin, George Davey Smith, Demetrius Albanes, Melinda C Aldrich, Angeline Andrew, Susanne M Arnold, Heike Bickeböller, Stig E Bojesen, Hans Brunnström, Jonas Manjer, Irene Brüske, Neil E Caporaso, Chu Chen, David C Christiani, W Jay Christian, Jennifer A Doherty, Eric J Duell, John K Field, Michael P A Davies, Michael W Marcus, Gary E Goodman, Kjell Grankvist, Aage Haugen, Yun-Chul Hong, Lambertus A Kiemeney, Erik H F M van der Heijden, Peter Kraft, Mikael B Johansson, Stephen Lam, Maria Teresa Landi, Philip Lazarus, Loïc Le Marchand, Geoffrey Liu, Olle Melander, Sungshim L Park, Gad Rennert, Angela Risch, Eric B Haura, Ghislaine Scelo, David Zaridze, Anush Mukeriya, Milan Savić, Jolanta Lissowska, Beata Swiatkowska, Vladimir Janout, Ivana Holcatova, Dana Mates, Matthew B Schabath, Hongbing Shen, Adonina Tardon, M Dawn Teare, Penella Woll, Ming-Sound Tsao, Xifeng Wu, Jian-Min Yuan, Rayjean J Hung, Christopher I Amos, James McKay, Paul Brennan

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An absolute risk model to identify individuals at elevated risk for pancreatic cancer in the general population. by Alison P Klein, Sara Lindström, Julie B Mendelsohn, Emily Steplowski, Alan A Arslan, H Bas Bueno-de-Mesquita, Charles S Fuchs, Steven Gallinger, Myron Gross, Kathy Helzlsouer, Elizabeth A Holly, Eric J Jacobs, Andrea Lacroix, Donghui Li, Margaret T Mandelson, Sara H Olson, Gloria M Petersen, Harvey A Risch, Rachael Z Stolzenberg-Solomon, Wei Zheng, Laufey Amundadottir, Demetrius Albanes, Naomi E Allen, William R Bamlet, Marie-Christine Boutron-Ruault, Julie E Buring, Paige M Bracci, Federico Canzian, Sandra Clipp, Michelle Cotterchio, Eric J Duell, Joanne Elena, J Michael Gaziano, Edward L Giovannucci, Michael Goggins, Göran Hallmans, Manal Hassan, Amy Hutchinson, David J Hunter, Charles Kooperberg, Robert C Kurtz, Simin Liu, Kim Overvad, Domenico Palli, Alpa V Patel, Kari G Rabe, Xiao-Ou Shu, Nadia Slimani, Geoffrey S Tobias, Dimitrios Trichopoulos, Stephen K Van Den Eeden, Paolo Vineis, Jarmo Virtamo, Jean Wactawski-Wende, Brian M Wolpin, Herbert Yu, Kai Yu, Anne Zeleniuch-Jacquotte, Stephen J Chanock, Robert N Hoover, Patricia Hartge, Peter Kraft

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Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. by Nancy L Saccone, Robert C Culverhouse, Tae-Hwi Schwantes-An, Dale S Cannon, Xiangning Chen, Sven Cichon, Ina Giegling, Shizhong Han, Younghun Han, Kaisu Keskitalo-Vuokko, Xiangyang Kong, Maria Teresa Landi, Jennie Z Ma, Susan E Short, Sarah H Stephens, Victoria L Stevens, Lingwei Sun, Yufei Wang, Angela S Wenzlaff, Steven H Aggen, Naomi Breslau, Peter Broderick, Nilanjan Chatterjee, Jingchun Chen, Andrew C Heath, Markku Heliövaara, Nicole R Hoft, David J Hunter, Majken K Jensen, Nicholas G Martin, Grant W Montgomery, Tianhua Niu, Thomas J Payne, Leena Peltonen, Michele L Pergadia, John P Rice, Richard Sherva, Margaret R Spitz, Juzhong Sun, Jen C Wang, Robert B Weiss, William Wheeler, Stephanie H Witt, Bao-Zhu Yang, Neil E Caporaso, Marissa A Ehringer, Tim Eisen, Susan M Gapstur, Joel Gelernter, Richard Houlston, Jaakko Kaprio, Kenneth S Kendler, Peter Kraft, Mark F Leppert, Ming D Li, Pamela A F Madden, Markus M Nöthen, Sreekumar Pillai, Marcella Rietschel, Dan Rujescu, Ann Schwartz, Christopher I Amos, Laura J Bierut

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GWAS meta-analysis identifies five susceptibility loci for endometrial cancerResearch in context by Dhanya Ramachandran, Xuemin Wang, Triin Laisk, Ying Zheng, Nathan Ingold, Daffodil M. Canson, Pik Fang Kho, Bianca J. Naumann, Carly J. Chapman, Kristine Bousset, Anna V. Krause, Peter Schürmann, Britta Wieland, Patricia Hanel, Fabienne Hülse, Norman Häfner, Ingo Runnebaum, Natalia Dubrowinskaja, Nurzhan Turmanov, Tatyana Yugay, Zura Berkutovna Yessimsiitova, Frédéric Amant, Daniela Annibali, Matthias W. Beckmann, Clara Bodelon, Daniel D. Buchanan, Chu Chen, Megan A. Clarke, Linda S. Cook, Immaculata De Vivo, Wout De Wispelaere, Mengmeng Du, Douglas F. Easton, Julius Emons, Peter A. Fasching, Christine M. Friedenreich, Grace Gallagher, Graham G. Giles, Ellen L. Goode, Holly R. Harris, David J. Hunter, David L. Kolin, Peter Kraft, James V. Lacey, Diether Lambrechts, Lingeng Lu, George L. Mutter, Jeffin Naduparambil, Kelli O’Connell, Alpa V. Patel, Paul D.P. Pharoah, Timothy R. Rebbeck, Fulvio Ricceri, Harvey A. Risch, Matthias Ruebner, Carlotta Sacerdote, Rodney J. Scott, V. Wendy Setiawan, Xiao-Ou Shu, Melissa C. Southey, Emma Tham, Ian Tomlinson, Constance Turman, Nicolas Wentzensen, Wanghong Xu, Herbert Yu, Wei Zheng, Amanda B. Spurdle, Yosef Yarden, Reedik Mägi, Peter Hillemanns, Dylan M. Glubb, Thilo Dörk, Tracy A. O’Mara

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Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. by John R B Perry, Benjamin F Voight, Loïc Yengo, Najaf Amin, Josée Dupuis, Martha Ganser, Harald Grallert, Pau Navarro, Man Li, Lu Qi, Valgerdur Steinthorsdottir, Robert A Scott, Peter Almgren, Dan E Arking, Yurii Aulchenko, Beverley Balkau, Rafn Benediktsson, Richard N Bergman, Eric Boerwinkle, Lori Bonnycastle, Noël P Burtt, Harry Campbell, Guillaume Charpentier, Francis S Collins, Christian Gieger, Todd Green, Samy Hadjadj, Andrew T Hattersley, Christian Herder, Albert Hofman, Andrew D Johnson, Anna Kottgen, Peter Kraft, Yann Labrune, Claudia Langenberg, Alisa K Manning, Karen L Mohlke, Andrew P Morris, Ben Oostra, James Pankow, Ann-Kristin Petersen, Peter P Pramstaller, Inga Prokopenko, Wolfgang Rathmann, William Rayner, Michael Roden, Igor Rudan, Denis Rybin, Laura J Scott, Gunnar Sigurdsson, Rob Sladek, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Jaakko Tuomilehto, Andre G Uitterlinden, Sidonie Vivequin, Michael N Weedon, Alan F Wright, MAGIC, DIAGRAM Consortium, GIANT Consortium, Frank B Hu, Thomas Illig, Linda Kao, James B Meigs, James F Wilson, Kari Stefansson, Cornelia van Duijn, David Altschuler, Andrew D Morris, Michael Boehnke, Mark I McCarthy, Philippe Froguel, Colin N A Palmer, Nicholas J Wareham, Leif Groop, Timothy M Frayling, Stéphane Cauchi

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