Computational eco‐systems biology in Tara Oceans: translating data into knowledge by Shinichi Sunagawa, Eric Karsenti, Chris Bowler, Peer Bork

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Evolution and functional cross‐talk of protein post‐translational modifications by Pedro Beltrao, Peer Bork, Nevan J. Krogan, Vera van Noort

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Computing Fuzzy Associations for the Analysis of Biological Literature by Carolina Perez-Iratxeta, Harindar S. Keer, Peer Bork, Miguel A. Andrade

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Systematic identification of proteins that elicit drug side effects by Michael Kuhn, Mumna Al Banchaabouchi, Monica Campillos, Lars Juhl Jensen, Cornelius Gross, Anne‐Claude Gavin, Peer Bork

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Prediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighbours by Takuji Yamada, Alison S Waller, Jeroen Raes, Aleksej Zelezniak, Nadia Perchat, Alain Perret, Marcel Salanoubat, Kiran R Patil, Jean Weissenbach, Peer Bork

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Transcription start site associated RNAs in bacteria by Eva Yus, Marc Güell, Ana P Vivancos, Wei‐Hua Chen, María Lluch‐Senar, Javier Delgado, Anne‐Claude Gavin, Peer Bork, Luis Serrano

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Colorectal Cancer and the Human Gut Microbiome: Reproducibility with Whole-Genome Shotgun Sequencing. by Emily Vogtmann, Xing Hua, Georg Zeller, Shinichi Sunagawa, Anita Y Voigt, Rajna Hercog, James J Goedert, Jianxin Shi, Peer Bork, Rashmi Sinha

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Deciphering a global network of functionally associated post‐translational modifications by Pablo Minguez, Luca Parca, Francesca Diella, Daniel R Mende, Runjun Kumar, Manuela Helmer‐Citterich, Anne‐Claude Gavin, Vera van Noort, Peer Bork

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Characterization of drug‐induced transcriptional modules: towards drug repositioning and functional understanding by Murat Iskar, Georg Zeller, Peter Blattmann, Monica Campillos, Michael Kuhn, Katarzyna H Kaminska, Heiko Runz, Anne‐Claude Gavin, Rainer Pepperkok, Vera van Noort, Peer Bork

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Coupling proteomics and metabolomics for the unsupervised identification of protein-metabolite interactions in Chaetomium thermophilum. by Yuanyue Li, Michael Kuhn, Joanna Zukowska-Kasprzyk, Marco L Hennrich, Panagiotis L Kastritis, Francis J O'Reilly, Prasad Phapale, Martin Beck, Anne-Claude Gavin, Peer Bork

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Cell type‐specific nuclear pores: a case in point for context‐dependent stoichiometry of molecular machines by Alessandro Ori, Niccolò Banterle, Murat Iskar, Amparo Andrés‐Pons, Claudia Escher, Huy Khanh Bui, Lenore Sparks, Victor Solis‐Mezarino, Oliver Rinner, Peer Bork, Edward A Lemke, Martin Beck

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Millimeter‐scale genetic gradients and community‐level molecular convergence in a hypersaline microbial mat by Victor Kunin, Jeroen Raes, J Kirk Harris, John R Spear, Jeffrey J Walker, Natalia Ivanova, Christian von Mering, Brad M Bebout, Norman R Pace, Peer Bork, Philip Hugenholtz

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Capturing protein communities by structural proteomics in a thermophilic eukaryote by Panagiotis L Kastritis, Francis J O'Reilly, Thomas Bock, Yuanyue Li, Matt Z Rogon, Katarzyna Buczak, Natalie Romanov, Matthew J Betts, Khanh Huy Bui, Wim J Hagen, Marco L Hennrich, Marie‐Therese Mackmull, Juri Rappsilber, Robert B Russell, Peer Bork, Martin Beck, Anne‐Claude Gavin

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Cross‐talk between phosphorylation and lysine acetylation in a genome‐reduced bacterium by Vera van Noort, Jan Seebacher, Samuel Bader, Shabaz Mohammed, Ivana Vonkova, Matthew J Betts, Sebastian Kühner, Runjun Kumar, Tobias Maier, Martina O'Flaherty, Vladimir Rybin, Arne Schmeisky, Eva Yus, Jörg Stülke, Luis Serrano, Robert B Russell, Albert JR Heck, Peer Bork, Anne‐Claude Gavin

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A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae by Oriol Gallego, Matthew J Betts, Jelena Gvozdenovic‐Jeremic, Kenji Maeda, Christian Matetzki, Carmen Aguilar‐Gurrieri, Pedro Beltran‐Alvarez, Stefan Bonn, Carlos Fernández‐Tornero, Lars Juhl Jensen, Michael Kuhn, Jamie Trott, Vladimir Rybin, Christoph W Müller, Peer Bork, Marko Kaksonen, Robert B Russell, Anne‐Claude Gavin

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Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome‐reduced bacterium by Maria Lluch‐Senar, Javier Delgado, Wei‐Hua Chen, Verónica Lloréns‐Rico, Francis J O'Reilly, Judith AH Wodke, E Besray Unal, Eva Yus, Sira Martínez, Robert J Nichols, Tony Ferrar, Ana Vivancos, Arne Schmeisky, Jörg Stülke, Vera van Noort, Anne‐Claude Gavin, Peer Bork, Luis Serrano

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Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria by Elisabetta Cacace, Manuela Tietgen, Meike Steinhauer, André Mateus, Tilman G. Schultze, Marina Eckermann, Marco Galardini, Vallo Varik, Alexandra Koumoutsi, Jordan J. Parzeller, Federico Corona, Askarbek Orakov, Michael Knopp, Amber Brauer-Nikonow, Peer Bork, Celia V. Romao, Michael Zimmermann, Peter Cloetens, Mikhail M. Savitski, Athanasios Typas, Stephan Göttig

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A conserved pilin from uncultured gut bacterial clade TANB77 enhances cancer immunotherapy by Chan Yeong Kim, Dong Jin Park, Beung Chul Ahn, Seungbyn Baek, Min Hee Hong, Linh Thanh Nguyen, Sun Ha Hwang, Nayeon Kim, Daniel Podlesny, Askarbek Orakov, Christian Schudoma, Shahriyar Mahdi Robbani, Hyo Sup Shim, Hong In Yoon, Chang Young Lee, Seong Yong Park, Dongeun Yong, Mina Han, Peer Bork, Byoung Choul Kim, Sang-Jun Ha, Hye Ryun Kim, Insuk Lee

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Potential of fecal microbiota for early‐stage detection of colorectal cancer by Georg Zeller, Julien Tap, Anita Y Voigt, Shinichi Sunagawa, Jens Roat Kultima, Paul I Costea, Aurélien Amiot, Jürgen Böhm, Francesco Brunetti, Nina Habermann, Rajna Hercog, Moritz Koch, Alain Luciani, Daniel R Mende, Martin A Schneider, Petra Schrotz‐King, Christophe Tournigand, Jeanne Tran Van Nhieu, Takuji Yamada, Jürgen Zimmermann, Vladimir Benes, Matthias Kloor, Cornelia M Ulrich, Magnus von Knebel Doeberitz, Iradj Sobhani, Peer Bork

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The postbiotic ReFerm® versus standard nutritional support in advanced alcohol-related liver disease (GALA-POSTBIO): a randomized controlled phase 2 trial by Johanne K. Hansen, Mads Israelsen, Suguru Nishijima, Sara E. Stinson, Peter Andersen, Stine Johansen, Camilla D. Hansen, Maximilian Joseph Brol, Sabine Klein, Robert Schierwagen, Frank Erhard Uschner, Karolina Sulek, Ida F. Villesen, Katrine P. Lindvig, Katrine H. Thorhauge, Nikolaj Torp, Jane M. Jensen, Marisa Isabell Keller, Gitte H. Jensen, Sönke Detlefsen, Diana J. Leeming, Evelina Stankevic, Tommi Suvitaival, Andressa Zawadzki, Michael Kuhn, Lars Juhl Jensen, Morten Karsdal, Jonel Trebicka, Hans Israelsen, Cristina Legido-Quigley, Peer Bork, Manimozhiyan Arumugam, Torben Hansen, Maja Thiele, Aleksander Krag

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