Deep mutagenesis scanning using whole trimeric SARS-CoV-2 spike highlights the importance of NTD-RBD interactions in determining spike phenotype. by Ruthiran Kugathasan, Ksenia Sukhova, Maya Moshe, Paul Kellam, Wendy Barclay

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A membrane topology model for human interferon inducible transmembrane protein 1. by Stuart Weston, Stephanie Czieso, Ian J White, Sarah E Smith, Paul Kellam, Mark Marsh

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No evidence of XMRV or related retroviruses in a London HIV-1-positive patient cohort. by Eleanor R Gray, Jeremy A Garson, Judith Breuer, Simon Edwards, Paul Kellam, Deenan Pillay, Greg J Towers

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Widespread Reassortment Shapes the Evolution and Epidemiology of Bluetongue Virus following European Invasion. by Kyriaki Nomikou, Joseph Hughes, Rachael Wash, Paul Kellam, Emmanuel Breard, Stéphan Zientara, Massimo Palmarini, Roman Biek, Peter Mertens

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Full genome virus detection in fecal samples using sensitive nucleic acid preparation, deep sequencing, and a novel iterative sequence classification algorithm. by Matthew Cotten, Bas Oude Munnink, Marta Canuti, Martin Deijs, Simon J Watson, Paul Kellam, Lia van der Hoek

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The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin. by Claire Pardieu, Raphaël Vigan, Sam J Wilson, Alessandra Calvi, Trinity Zang, Paul Bieniasz, Paul Kellam, Greg J Towers, Stuart J D Neil

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Specific capture and whole-genome sequencing of viruses from clinical samples. by Daniel P Depledge, Anne L Palser, Simon J Watson, Imogen Yi-Chun Lai, Eleanor R Gray, Paul Grant, Ravinder K Kanda, Emily Leproust, Paul Kellam, Judith Breuer

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RNA-seq analysis of host and viral gene expression highlights interaction between varicella zoster virus and keratinocyte differentiation. by Meleri Jones, Inga R Dry, Dan Frampton, Manuraj Singh, Ravinder K Kanda, Michael B Yee, Paul Kellam, Michael Hollinshead, Paul R Kinchington, Edel A O'Toole, Judith Breuer

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Transmission of equine influenza virus during an outbreak is characterized by frequent mixed infections and loose transmission bottlenecks. by Joseph Hughes, Richard C Allen, Marc Baguelin, Katie Hampson, Gregory J Baillie, Debra Elton, J Richard Newton, Paul Kellam, James L N Wood, Edward C Holmes, Pablo R Murcia

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Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model. by Aaron R Everitt, Simon Clare, Jacqueline U McDonald, Leanne Kane, Katherine Harcourt, Malika Ahras, Amar Lall, Christine Hale, Angela Rodgers, Douglas B Young, Ashraful Haque, Oliver Billker, John S Tregoning, Gordon Dougan, Paul Kellam

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Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1. by Laura E McCoy, Lucy Rutten, Dan Frampton, Ian Anderson, Luke Granger, Rachael Bashford-Rogers, Gillian Dekkers, Nika M Strokappe, Michael S Seaman, Willie Koh, Vanina Grippo, Alexander Kliche, Theo Verrips, Paul Kellam, Ariberto Fassati, Robin A Weiss

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Antibody response to SARS-CoV-2 infection in humans: A systematic review. by Nathan Post, Danielle Eddy, Catherine Huntley, May C I van Schalkwyk, Madhumita Shrotri, David Leeman, Samuel Rigby, Sarah V Williams, William H Bermingham, Paul Kellam, John Maher, Adrian M Shields, Gayatri Amirthalingam, Sharon J Peacock, Sharif A Ismail

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T cell response to SARS-CoV-2 infection in humans: A systematic review. by Madhumita Shrotri, May C I van Schalkwyk, Nathan Post, Danielle Eddy, Catherine Huntley, David Leeman, Samuel Rigby, Sarah V Williams, William H Bermingham, Paul Kellam, John Maher, Adrian M Shields, Gayatri Amirthalingam, Sharon J Peacock, Sharif A Ismail

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Evolution of an Eurasian avian-like influenza virus in naïve and vaccinated pigs. by Pablo R Murcia, Joseph Hughes, Patrizia Battista, Lucy Lloyd, Gregory J Baillie, Ricardo H Ramirez-Gonzalez, Doug Ormond, Karen Oliver, Debra Elton, Jennifer A Mumford, Mario Caccamo, Paul Kellam, Bryan T Grenfell, Edward C Holmes, James L N Wood

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Intranasal delivery of mRNA expressing newly identified Acinetobacter baumannii antigens protects against bacterial lung disease by Sophie L. Higham, Ziyin Wang, Valarmathy Murugaiah, Jihye Song, Chubicka Thomas, Houze Zhang, Uta Griesenbach, Eric W. F. W. Alton, Luke A. Granger, Andrea Flores Esparza, Beatriz Dias Barbieri, Paul G. Hitchen, Paul Kellam, Robin J. Shattock, Shiranee Sriskandan, Stephen T. Reece, John S. Tregoning

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Correction: Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe. by François Blanquart, Chris Wymant, Marion Cornelissen, Astrid Gall, Margreet Bakker, Daniela Bezemer, Matthew Hall, Mariska Hillebregt, Swee Hoe Ong, Jan Albert, Norbert Bannert, Jacques Fellay, Katrien Fransen, Annabelle J Gourlay, M Kate Grabowski, Barbara Gunsenheimer-Bartmeyer, Huldrych F Günthard, Pia Kivelä, Roger Kouyos, Oliver Laeyendecker, Kirsi Liitsola, Laurence Meyer, Kholoud Porter, Matti Ristola, Ard van Sighem, Guido Vanham, Ben Berkhout, Paul Kellam, Peter Reiss, Christophe Fraser, BEEHIVE collaboration

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Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe. by François Blanquart, Chris Wymant, Marion Cornelissen, Astrid Gall, Margreet Bakker, Daniela Bezemer, Matthew Hall, Mariska Hillebregt, Swee Hoe Ong, Jan Albert, Norbert Bannert, Jacques Fellay, Katrien Fransen, Annabelle J Gourlay, M Kate Grabowski, Barbara Gunsenheimer-Bartmeyer, Huldrych F Günthard, Pia Kivelä, Roger Kouyos, Oliver Laeyendecker, Kirsi Liitsola, Laurence Meyer, Kholoud Porter, Matti Ristola, Ard van Sighem, Guido Vanham, Ben Berkhout, Paul Kellam, Peter Reiss, Christophe Fraser, BEEHIVE collaboration

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HIV-phyloTSI: subtype-independent estimation of time since HIV-1 infection for cross-sectional measures of population incidence using deep sequence data by Tanya Golubchik, Lucie Abeler-Dörner, Matthew Hall, Chris Wymant, David Bonsall, George Macintyre-Cockett, Laura Thomson, Jared M. Baeten, Connie L. Celum, Ronald M. Galiwango, Barry Kosloff, Mohammed Limbada, Andrew Mujugira, Nelly R. Mugo, Astrid Gall, François Blanquart, Margreet Bakker, Daniela Bezemer, Swee Hoe Ong, Jan Albert, Norbert Bannert, Jacques Fellay, Barbara Gunsenheimer-Bartmeyer, Huldrych F. Günthard, Pia Kivelä, Roger D. Kouyos, Laurence Meyer, Kholoud Porter, Ard van Sighem, Mark van der Valk, Ben Berkhout, Paul Kellam, Marion Cornelissen, Peter Reiss, Helen Ayles, David N. Burns, Sarah Fidler, Mary Kate Grabowski, Richard Hayes, Joshua T. Herbeck, Joseph Kagaayi, Pontiano Kaleebu, Jairam R. Lingappa, Deogratius Ssemwanga, Susan H. Eshleman, Myron S. Cohen, Oliver Ratmann, Oliver Laeyendecker, Christophe Fraser, the HPTN 071 (PopART) Phylogenetics protocol team, the BEEHIVE consortium and the PANGEA consortium

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