Gender differences in survival and the use of primary care prior to diagnosis of three cancers: an analysis of routinely collected UK general practice data. by Yingying Wang, Nick Freemantle, Irwin Nazareth, Kate Hunt

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Beliefs of Health Care Providers, Lay Health Care Providers and Lay Persons in Nigeria Regarding Hypertension. A Systematic Mixed Studies Review. by James Tosin Akinlua, Richard Meakin, Philip Fadahunsi, Nick Freemantle

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Current Prevalence Pattern of Hypertension in Nigeria: A Systematic Review. by James Tosin Akinlua, Richard Meakin, Aminu Mahmoud Umar, Nick Freemantle

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Antibiotic prescribing for lower UTI in elderly patients in primary care and risk of bloodstream infection: A cohort study using electronic health records in England. by Laura Shallcross, Patrick Rockenschaub, Ruth Blackburn, Irwin Nazareth, Nick Freemantle, Andrew Hayward

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Variation in recorded child maltreatment concerns in UK primary care records: a cohort study using The Health Improvement Network (THIN) database. by Jenny Woodman, Nick Freemantle, Janice Allister, Simon de Lusignan, Ruth Gilbert, Irene Petersen

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Understanding patients' adherence-related beliefs about medicines prescribed for long-term conditions: a meta-analytic review of the Necessity-Concerns Framework. by Rob Horne, Sarah C E Chapman, Rhian Parham, Nick Freemantle, Alastair Forbes, Vanessa Cooper

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Methylphenidate versus placebo for fatigue in patients with advanced cancer: the MePFAC randomised controlled trial by Patrick Stone, Ollie Minton, Alison Richardson, Peter Buckle, Zinat E Enayat, Louise Marston, Nick Freemantle

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Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): statistical analysis plan for a randomised controlled trial by Norin Ahmed, Hakim-Moulay Dehbi, Nick Freemantle, Jonathan Best, Philip S. Nash, James K. Ruffle, David Doig, David J. Werring

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Rationale and methodology for a European pooled analysis of postmarketing interventional and observational studies of insulin glargine 300 U/mL in diabetes: protocol of REALI proje... by Nick Freemantle, Didac Mauricio, Riccardo C Bonadonna, Pierre Gourdy, Dirk Mueller-Wieland, Gregory Bigot, Alice Ciocca, Celine Mauquoi, Mélissa Rollot, Mireille Bonnemaire

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Dupilumab versus Lebrikizumab Demonstrates Greater Likelihood of Achieving and Maintaining Improvements in Efficacy Outcomes Using a Placebo-Adjusted Indirect Treatment Comparison by Sonja Ständer, Andreas Pinter, Firas G. Hougeir, Patricia Guyot, Yingxin Xu, Amy H. Praestgaard, Nick Freemantle, Ana B. Rossi, Gaëlle Bégo-Le-Bagousse, Zhixiao Wang, Kerry Noonan, Mike Bastian

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High-dose vitamin D3 to improve outcomes in the convalescent phase of complicated severe acute malnutrition in Pakistan: a double-blind randomised controlled trial (ViDiSAM) by Javeria Saleem, Rubeena Zakar, Muhammad Salman Butt, Rameeza Kaleem, Asif Chaudhary, Jaya Chandna, David A. Jolliffe, Joseph Piper, Zaigham Abbas, Jonathan C. Y. Tang, William D. Fraser, Nick Freemantle, Andrew J. Prendergast, Adrian R. Martineau

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Randomised controlled trial of gradual antipsychotic reduction and discontinuation in people with schizophrenia and related disorders: the RADAR trial (Research into Antipsychotic... by Rachael Hunter, Louise Marston, Nick Freemantle, Sonia Johnson, Joanna Moncrieff, Vanessa Pinfold, Stefan Priebe, Robert Horne, Thomas R E Barnes, Glyn Lewis, Nicola Morant, Lyn J Kent, Ruth Smith, Katherine Darton, Nadia E Crellin, Ruth E Cooper

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Favipiravir, lopinavir-ritonavir, or combination therapy (FLARE): A randomised, double-blind, 2 × 2 factorial placebo-controlled trial of early antiviral therapy in COVID-19. by David M Lowe, Li-An K Brown, Kashfia Chowdhury, Stephanie Davey, Philip Yee, Felicia Ikeji, Amalia Ndoutoumou, Divya Shah, Alexander Lennon, Abhulya Rai, Akosua A Agyeman, Anna Checkley, Nicola Longley, Hakim-Moulay Dehbi, Nick Freemantle, Judith Breuer, Judith Breuer, Joseph F Standing, FLARE Investigators

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VIVALDI-CT shaping care home COVID-19 testing policy: A pragmatic cluster randomised controlled trial of asymptomatic testing compared to standard care in care home staff. by Oliver Stirrup, James Blackstone, Iona Cullen-Stephenson, Robert Fenner, Natalie Adams, Ruth Leiser, Maria Krutikov, Borscha Azmi, Nick Freemantle, Adam Gordon, Martyn Regan, Martin Knapp, Lara Goscé, Catherine Henderson, Susan Hopkins, Arpana Verma, Jackie Cassell, Dorina Cadar, Tom Fowler, Andrew Copas, Paul Flowers, Laura Shallcross

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SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study by Judith Breuer, Catherine F Houlihan, Nick Freemantle, David Partridge, Gaia Nebbia, Jacqui Prieto, Gee Yen Shin, Andrew Copas, Oliver Stirrup, Kenneth Laing, Rachel Williams, Helen Wheeler, Paul Randell, Ana da Silva Filipe, Maria-Teresa Cutino-Moguel, Tommy Rampling, Tabassum Khan, James Price, Eleni Nastouli, Katie Johnson, Sharon Glaysher, Scott Elliott, Helen Umpleby, Emanuela Pelosi, Emma Thomson, Cristina Venturini, Anna Riddell, Alison Cox, Andrew C Hayward, Malin Bergström, David Harrington, Charlotte Williams, Tanzina Haque, Dianne Irish, Adrienn Angyal, Marios Margaritis, Moira Spyer, Florencia Boshier, José Afonso Guerra-Assunção, Adela Alcolea-Medina, Angela Beckett, Themoula Charalampous, Raghavendran Kulasegaran Shylini, Beatrix Kele, Irene Monahan, Guy Mollett, Matthew Parker, Sunando Roy, Joshua Taylor, Sophie Weller, Eleri Wilson-Davies, Phillip Wade, Joseph Hughes, Tabitha Mahungu, Cassie Pope, Samuel Robson, Kordo Saeed, Thushan de Silva, Luke Snell, Adam A Witney, James Blackstone, Leanne Hockey, Georgia Marley, Christine Peters, Flavia Flaviani, Bindi Patel, Tom G S Williams, Rahul Batra, Jonathan D Edgeworth, Pinglawathee Madona, Jennifer Hart, Juanita Pang, Helena Tutill, Nadua Bayzid, Marius Cotic, Luke Green, Benjamin Lindsey, Amy State, Alison Cope, Peijun Zhang, Max Whiteley, Marta Gallis Ramalho, Stella Christou, Stavroula Louka, Hailey Hornsby, Benjamin Foulkes, Paige Wolverson, Joe Heffer, Nikki Smith, Salman Goudarzi, Chris Fearn, Kate Cook, Katie Loveson, Adhyana Mahamana, Buddhini Samaraweera, Siona Silveira, Stephen Aplin, Sarah Jeremiah, Matthew Harvey, Thea Sass, Ngee Keong Tan, Claudia Cardoso Pereira, Dan Frampton, Matt Byott, Judith Heaney, Emilie Sanchez, Stavroula M Paraskevopoulou

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