CD4 rate of increase is preferred to CD4 threshold for predicting outcomes among virologically suppressed HIV-infected adults on antiretroviral therapy. by Sol Aldrete, Jeong Hoon Jang, Kirk A Easley, Jason Okulicz, Tian Dai, Yi No Chen, Maria Pino, Brian K Agan, Ryan C Maves, Mirko Paiardini, Vincent C Marconi

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Intact type I Interferon production and IRF7 function in sooty mangabeys. by Steven E Bosinger, Zachary P Johnson, Kathryn A Folkner, Nirav Patel, Tayebeh Hashempour, Simon P Jochems, Perla M Del Rio Estrada, Mirko Paiardini, Rongtuan Lin, Thomas H Vanderford, John Hiscott, Guido Silvestri

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Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21. by Suresh Pallikkuth, Luca Micci, Zachary S Ende, Robin I Iriele, Barbara Cervasi, Benton Lawson, Colleen S McGary, Kenneth A Rogers, James G Else, Guido Silvestri, Kirk Easley, Jacob D Estes, Francois Villinger, Savita Pahwa, Mirko Paiardini

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Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques. by Sarah J Byrnes, Kathleen Busman-Sahay, Thomas A Angelovich, Skyler Younger, Sol Taylor-Brill, Michael Nekorchuk, Stephen Bondoc, Rachel Dannay, Margaret Terry, Catherine R Cochrane, Trisha A Jenkins, Michael Roche, Claire Deleage, Steven E Bosinger, Mirko Paiardini, Bruce J Brew, Jacob D Estes, Melissa J Churchill

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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells. by Luca Micci, Xavier Alvarez, Robin I Iriele, Alexandra M Ortiz, Emily S Ryan, Colleen S McGary, Claire Deleage, Brigitte B McAtee, Tianyu He, Cristian Apetrei, Kirk Easley, Savita Pahwa, Ronald G Collman, Cynthia A Derdeyn, Miles P Davenport, Jacob D Estes, Guido Silvestri, Andrew A Lackner, Mirko Paiardini

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Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals. by Nichole R Klatt, Steven E Bosinger, Melicent Peck, Laura E Richert-Spuhler, Anke Heigele, Jillian P Gile, Nirav Patel, Jessica Taaffe, Boris Julg, David Camerini, Carlo Torti, Jeffrey N Martin, Steven G Deeks, Elizabeth Sinclair, Frederick M Hecht, Michael M Lederman, Mirko Paiardini, Frank Kirchhoff, Jason M Brenchley, Peter W Hunt, Guido Silvestri

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EZH2 inhibition mitigates HIV immune evasion, reduces reservoir formation, and promotes skewing of CD8+ T cells toward less-exhausted phenotypes by Andrea Gramatica, Itzayana G. Miller, Adam R. Ward, Farzana Khan, Tyler J. Kemmer, Jared Weiler, Tan Thinh Huynh, Paul Zumbo, Andrew P. Kurland, Louise Leyre, Yanqin Ren, Thais Klevorn, Dennis C. Copertino, Uchenna Chukwukere, Callie Levinger, Thomas R. Dilling, Noemi Linden, Nathan L. Board, Emma Falling Iversen, Sandra Terry, Talia M. Mota, Seden Bedir, Kiera L. Clayton, Alberto Bosque, Lynsay MacLaren Ehui, Colin Kovacs, Doron Betel, Jeffry R. Johnson, Mirko Paiardini, Ali Danesh, R. Brad Jones

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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques. by Christopher T Edwards, Kirti A Karunakaran, Elijah Garcia, Nathan Beutler, Matthew Gagne, Nadia Golden, Hadj Aoued, Kathryn L Pellegrini, Matthew R Burnett, Christopher Cole Honeycutt, Stacey A Lapp, Thang Ton, Mark C Lin, Amanda Metz, Andrei Bombin, Kelly Goff, Sarah E Scheuermann, Amelia Wilkes, Jennifer S Wood, Stephanie Ehnert, Stacey Weissman, Elizabeth H Curran, Melissa Roy, Evan Dessasau, Mirko Paiardini, Amit A Upadhyay, Ian N Moore, Nicholas J Maness, Daniel C Douek, Anne Piantadosi, Raiees Andrabi, Thomas R Rogers, Dennis R Burton, Steven E Bosinger

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