Towards novel BIOmarkers to diagnose SEPsis (BIOSEP) in the emergency room: a protocol for a multicentre, prospective cohort study by Tom van der Poll, W Joost Wiersinga, Michiel Schinkel, Renee A Douma, Hazra S Moeniralam, Marleen A Slim, Evelien Reijnders, Oren Turgman, Sebastiaan C M Joosten, Hessel Peters-Sengers

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Immunobiological effects of tocilizumab across respiratory subphenotypes in COVID-19 ARDS by Emma Rademaker, Daan F. L. Filippini, Jelle L. G. Haitsma Mulier, Marleen A. Slim, Rombout B. E. van Amstel, Sivasubramanium V. Bhavani, Nicole P. Juffermans, Harm-Jan S. de Grooth, Lennie P. G. Derde, Olaf L. Cremer, Lieuwe D. J. Bos, Amsterdam U. M. C. COVID-19 Biobank Study Group

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A phase I trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenously administered low-anticoagulant heparin (M6229) in critically ill sepsis... by Niels van Mourik, Rombout B. E. van Amstel, Marleen A. Slim, Lonneke A. van Vught, Tom van der Poll, Joram Huckriede, Femke de Vries, Sjef J. de Kimpe, Raf Crabbé, Simone J. M. van Leeuwen, Peter F. Ekhart, Chris P. M. Reutelingsperger, Gerry A. F. Nicolaes, Alexander P. J. Vlaar, Marcella C. A. Müller

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ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol by Peter Pickkers, Evangelos J Giamarellos-Bourboulis, Mihai G Netea, Michael Bauer, Mihaela Lupse, Frank Bloos, Tom van der Poll, W Joost Wiersinga, Thierry Calandra, Sylvain Meylan, Alexander P J Vlaar, Sebastian Weis, Marleen A Slim, Niels van Mourik, Marcella C A Müller, Antigone Kotsaki, Lonneke van Vught, Aline de Nooijer, Lieke Bakkerus, Nikolaos Antonakos

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Clinical Subtype Trajectories in Sepsis Patients Admitted to the ICU: A Secondary Analysis of an Observational Study by Marleen A. Slim, MD, Rombout B. E. van Amstel, MD, Marcella C.A. Müller, MD, PhD, Olaf L. Cremer, MD, PhD, Alexander P. J. Vlaar, MD, PhD, Tom van der Poll, MD, PhD, W. Joost Wiersinga, MD, PhD, Christopher W. Seymour, MD, MSc, Lonneke A. van Vught, MD, PhD, MARS Consortium

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