Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci. by Martijn van de Bunt, Adrian Cortes, IGAS Consortium, Matthew A Brown, Andrew P Morris, Mark I McCarthy

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Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study. by Michael Wainberg, Anubha Mahajan, Anshul Kundaje, Mark I McCarthy, Erik Ingelsson, Nasa Sinnott-Armstrong, Manuel A Rivas

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A Protein Domain and Family Based Approach to Rare Variant Association Analysis. by Tom G Richardson, Hashem A Shihab, Manuel A Rivas, Mark I McCarthy, Colin Campbell, Nicholas J Timpson, Tom R Gaunt

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Metabolic profiling in Maturity-onset diabetes of the young (MODY) and young onset type 2 diabetes fails to detect robust urinary biomarkers. by Anna L Gloyn, Johan H Faber, Daniel Malmodin, Gaya Thanabalasingham, Francis Lam, Per Magne Ueland, Mark I McCarthy, Katharine R Owen, Dorrit Baunsgaard

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Burden of Diabetes and First Evidence for the Utility of HbA1c for Diagnosis and Detection of Diabetes in Urban Black South Africans: The Durban Diabetes Study. by Thomas R Hird, Fraser J Pirie, Tonya M Esterhuizen, Brian O'Leary, Mark I McCarthy, Elizabeth H Young, Manjinder S Sandhu, Ayesha A Motala

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Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable. by Debbie A Lawlor, Nicholas J Timpson, Roger M Harbord, Sam Leary, Andy Ness, Mark I McCarthy, Timothy M Frayling, Andrew T Hattersley, George Davey Smith

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The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis. by Martijn van de Bunt, Kyle J Gaulton, Leopold Parts, Ignasi Moran, Paul R Johnson, Cecilia M Lindgren, Jorge Ferrer, Anna L Gloyn, Mark I McCarthy

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Contribution of 32 GWAS-identified common variants to severe obesity in European adults referred for bariatric surgery. by Reedik Mägi, Sean Manning, Ahmed Yousseif, Andrea Pucci, Ferruccio Santini, Efthimia Karra, Giorgia Querci, Caterina Pelosini, Mark I McCarthy, Cecilia M Lindgren, Rachel L Batterham

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BMI-associated alleles do not constitute risk alleles for polycystic ovary syndrome independently of BMI: a case-control study. by Yvonne V Louwers, Nigel W Rayner, Blanca M Herrera, Lisette Stolk, Christopher J Groves, Thomas M Barber, Andre G Uitterlinden, Stephen Franks, Joop S E Laven, Mark I McCarthy

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Combining information from common type 2 diabetes risk polymorphisms improves disease prediction. by Michael N Weedon, Mark I McCarthy, Graham Hitman, Mark Walker, Christopher J Groves, Eleftheria Zeggini, N William Rayner, Beverley Shields, Katharine R Owen, Andrew T Hattersley, Timothy M Frayling

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Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies. by Robin N Beaumont, Sarah J Kotecha, Andrew R Wood, Bridget A Knight, Sylvain Sebert, Mark I McCarthy, Andrew T Hattersley, Marjo-Riitta Järvelin, Nicholas J Timpson, Rachel M Freathy, Sailesh Kotecha

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Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent. by Neelam Hassanali, N Maneka G De Silva, Neil Robertson, N William Rayner, Amy Barrett, Amanda J Bennett, Christopher J Groves, David R Matthews, Prasad Katulanda, Timothy M Frayling, Mark I McCarthy

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Glycosylation of immunoglobulin g: role of genetic and epigenetic influences. by Cristina Menni, Toma Keser, Massimo Mangino, Jordana T Bell, Idil Erte, Irena Akmačić, Frano Vučković, Maja Pučić Baković, Olga Gornik, Mark I McCarthy, Vlatka Zoldoš, Tim D Spector, Gordan Lauc, Ana M Valdes

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The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue. by Alexander W Drong, George Nicholson, Asa K Hedman, Eshwar Meduri, Elin Grundberg, Kerrin S Small, So-Youn Shin, Jordana T Bell, Fredrik Karpe, Nicole Soranzo, Tim D Spector, Mark I McCarthy, Panos Deloukas, Mattias Rantalainen, Cecilia M Lindgren, MolPAGE Consortia

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The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines. by Décio L Eizirik, Michael Sammeth, Thomas Bouckenooghe, Guy Bottu, Giorgia Sisino, Mariana Igoillo-Esteve, Fernanda Ortis, Izortze Santin, Maikel L Colli, Jenny Barthson, Luc Bouwens, Linda Hughes, Lorna Gregory, Gerton Lunter, Lorella Marselli, Piero Marchetti, Mark I McCarthy, Miriam Cnop

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Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors. by Martijn van de Bunt, Jocelyn E Manning Fox, Xiaoqing Dai, Amy Barrett, Caleb Grey, Lei Li, Amanda J Bennett, Paul R Johnson, Raymond V Rajotte, Kyle J Gaulton, Emmanouil T Dermitzakis, Patrick E MacDonald, Mark I McCarthy, Anna L Gloyn

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MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven. by Mattias Rantalainen, Blanca M Herrera, George Nicholson, Rory Bowden, Quin F Wills, Josine L Min, Matt J Neville, Amy Barrett, Maxine Allen, Nigel W Rayner, Jan Fleckner, Mark I McCarthy, Krina T Zondervan, Fredrik Karpe, Chris C Holmes, Cecilia M Lindgren

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Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults. by Ling Lu, Derrick A Bennett, Iona Y Millwood, Sarah Parish, Mark I McCarthy, Anubha Mahajan, Xu Lin, Fiona Bragg, Yu Guo, Michael V Holmes, Shoaib Afzal, Børge G Nordestgaard, Zheng Bian, Michael Hill, Robin G Walters, Liming Li, Zhengming Chen, Robert Clarke

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Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes. by Josine L Min, George Nicholson, Ingileif Halgrimsdottir, Kristian Almstrup, Andreas Petri, Amy Barrett, Mary Travers, Nigel W Rayner, Reedik Mägi, Fredrik H Pettersson, John Broxholme, Matt J Neville, Quin F Wills, Jane Cheeseman, GIANT Consortium, MolPAGE Consortium, Maxine Allen, Chris C Holmes, Tim D Spector, Jan Fleckner, Mark I McCarthy, Fredrik Karpe, Cecilia M Lindgren, Krina T Zondervan

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Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus. by Christopher G Bell, Sarah Finer, Cecilia M Lindgren, Gareth A Wilson, Vardhman K Rakyan, Andrew E Teschendorff, Pelin Akan, Elia Stupka, Thomas A Down, Inga Prokopenko, Ian M Morison, Jonathan Mill, Ruth Pidsley, International Type 2 Diabetes 1q Consortium, Panos Deloukas, Timothy M Frayling, Andrew T Hattersley, Mark I McCarthy, Stephan Beck, Graham A Hitman

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