Discordance and bleeding in critically ill patients with COVID-19 receiving unfractionated heparin: A comparison between aPTT and anti-factor Xa activity level monitoring by Merijn C. Reuland, Thijs F. van Haaps, Pieter O.L.P. Broeren, Nick van Es, Claire E. Dijkslag-van der Laan, Alexander P.J. Vlaar, Michiel Coppens, Marcella C.A. Müller

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Hemostatic conditions following autologous transfusion of fresh vs stored platelets in experimental endotoxemia: an open-label randomized controlled trial with healthy volunteers by Stefan F. van Wonderen, Floor L.F. van Baarle, Anita M. Tuip-de Boer, Chantal A. Polet, Robin van Bruggen, Christie Vermeulen, Thomas R.L. Klei, Chi M. Hau, Rienk Nieuwland, Cornelis van ’t Veer, Anna L. Peters, Sanne de Bruin, Alexander P.J. Vlaar, Bart J. Biemond, Marcella C.A. Müller

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A phase I trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenously administered low-anticoagulant heparin (M6229) in critically ill sepsis... by Niels van Mourik, Rombout B. E. van Amstel, Marleen A. Slim, Lonneke A. van Vught, Tom van der Poll, Joram Huckriede, Femke de Vries, Sjef J. de Kimpe, Raf Crabbé, Simone J. M. van Leeuwen, Peter F. Ekhart, Chris P. M. Reutelingsperger, Gerry A. F. Nicolaes, Alexander P. J. Vlaar, Marcella C. A. Müller

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ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol by Peter Pickkers, Evangelos J Giamarellos-Bourboulis, Mihai G Netea, Michael Bauer, Mihaela Lupse, Frank Bloos, Tom van der Poll, W Joost Wiersinga, Thierry Calandra, Sylvain Meylan, Alexander P J Vlaar, Sebastian Weis, Marleen A Slim, Niels van Mourik, Marcella C A Müller, Antigone Kotsaki, Lonneke van Vught, Aline de Nooijer, Lieke Bakkerus, Nikolaos Antonakos

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Clinical Subtype Trajectories in Sepsis Patients Admitted to the ICU: A Secondary Analysis of an Observational Study by Marleen A. Slim, MD, Rombout B. E. van Amstel, MD, Marcella C.A. Müller, MD, PhD, Olaf L. Cremer, MD, PhD, Alexander P. J. Vlaar, MD, PhD, Tom van der Poll, MD, PhD, W. Joost Wiersinga, MD, PhD, Christopher W. Seymour, MD, MSc, Lonneke A. van Vught, MD, PhD, MARS Consortium

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