How HIV-1 Uses the Metabolite Inositol Hexakisphosphate to Build Its Capsid by Leo C. James

Get full text

TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus. by Ruth E Watkinson, William A McEwan, Jerry C H Tam, Marina Vaysburd, Leo C James

Get full text

A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly. by Nadine Renner, Donna L Mallery, K M Rifat Faysal, Wang Peng, David A Jacques, Till Böcking, Leo C James

Get full text

Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity. by Laura M J Ylinen, Amanda J Price, Jane Rasaiyaah, Stéphane Hué, Nicola J Rose, Flavia Marzetta, Leo C James, Greg J Towers

Get full text

CPSF6 defines a conserved capsid interface that modulates HIV-1 replication. by Amanda J Price, Adam J Fletcher, Torsten Schaller, Tom Elliott, KyeongEun Lee, Vineet N KewalRamani, Jason W Chin, Greg J Towers, Leo C James

Get full text

Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly. by Amanda J Price, David A Jacques, William A McEwan, Adam J Fletcher, Sebastian Essig, Jason W Chin, Upul D Halambage, Christopher Aiken, Leo C James

Get full text

Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion. by Guido Papa, Donna L Mallery, Anna Albecka, Lawrence G Welch, Jérôme Cattin-Ortolá, Jakub Luptak, David Paul, Harvey T McMahon, Ian G Goodfellow, Andrew Carter, Sean Munro, Leo C James

Get full text

HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2. by Karen E Ocwieja, Troy L Brady, Keshet Ronen, Alyssa Huegel, Shoshannah L Roth, Torsten Schaller, Leo C James, Greg J Towers, John A T Young, Sumit K Chanda, Renate König, Nirav Malani, Charles C Berry, Frederic D Bushman

Get full text

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency. by Torsten Schaller, Karen E Ocwieja, Jane Rasaiyaah, Amanda J Price, Troy L Brady, Shoshannah L Roth, Stéphane Hué, Adam J Fletcher, KyeongEun Lee, Vineet N KewalRamani, Mahdad Noursadeghi, Richard G Jenner, Leo C James, Frederic D Bushman, Greg J Towers

Get full text

An intranasal subunit vaccine induces protective systemic and mucosal antibody immunity against respiratory viruses in mouse models by Aina Karen Anthi, Anette Kolderup, Eline Benno Vaage, Malin Bern, Sopisa Benjakul, Elias Tjärnhage, Fulgencio Ruso-Julve, Kjell-Rune Jensen, Heidrun Elisabeth Lode, Marina Vaysburd, Jeannette Nilsen, Marie Leangen Herigstad, Siri Aastedatter Sakya, Lisa Tietze, Diego Pilati, Mari Nyquist-Andersen, Mirjam Dürkoop, Torleif Tollefsrud Gjølberg, Linghang Peng, Stian Foss, Morten C. Moe, Benjamin E. Low, Michael V. Wiles, David Nemazee, Frode L. Jahnsen, John Torgils Vaage, Kenneth A. Howard, Inger Sandlie, Leo C. James, Gunnveig Grødeland, Fridtjof Lund-Johansen, Jan Terje Andersen

Get full text