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Correction of pathogenic mitochondrial DNA in patient-derived disease models using mitochondrial base editors by Indi P. Joore, Sawsan Shehata, Irena Muffels, Jose Castro-Alpízar, Elena Jiménez-Curiel, Emilia Nagyova, Natacha Levy, Ziqin Tang, Kimberly Smit, Wilbert P. Vermeij, Richard Rodenburg, Raymond Schiffelers, Edward E.S. Nieuwenhuis, Peter M. van Hasselt, Sabine A. Fuchs, Martijn A. J. Koppens
Published 2025-06-01Get full text
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Correction of pathogenic mitochondrial DNA in patient-derived disease models using mitochondrial base editors. by Indi P Joore, Sawsan Shehata, Irena Muffels, Jose Castro-Alpízar, Elena Jiménez-Curiel, Emilia Nagyova, Natacha Levy, Ziqin Tang, Kimberly Smit, Wilbert P Vermeij, Richard Rodenburg, Raymond Schiffelers, Edward E S Nieuwenhuis, Peter M van Hasselt, Sabine A Fuchs, Martijn A J Koppens
Published 2025-06-01Get full text
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High protein intake causes gene-length-dependent transcriptional decline, shortens lifespan and accelerates ageing in progeroid DNA repair-deficient mice by Ivar van Galen, Maria B. Birkisdóttir, Rutger A. Ozinga, Renata M. C. Brandt, Sander Barnhoorn, Sandra Imholz, Conny T. van Oostrom, Ricfrid W. G. N. van der Marel, Kimberly Smit, Yvonne M. A. Rijksen, Erwin Reiling, Harry van Steeg, Jan H. J. Hoeijmakers, Martijn E. T. Dollé, Wilbert P. Vermeij
Published 2025-05-01Get full text
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