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Saturated fat exacerbates mitochondrial dysfunction through remodelling of ATP production and inflammation in Barrett’s oesophagus compared to monounsaturated fat, particularly in... by Kathleen A.J. Mitchelson, Fiona O’Connell, Kieran Wynne, David Matallanas, Jacintha O’Sullivan, Helen M. Roche
Published 2025-08-01Get full text
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Proteomic compensation by paralogs preserves protein interaction networks after gene loss in cancer by Anjan Venkatesh, Niall Quinn, Swathi Ramachandra Upadhya, Barbara De Kegel, Alfonso Bolado Carrancio, Thomas Lefeivre, Olivier Dennler, Kieran Wynne, Alexander von Kriegsheim, Colm J Ryan
Published 2025-05-01Get full text
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The fibrin-derived peptide FX06 protects human pulmonary endothelial cells against the COVID-19-triggered cytokine storm by Zhiran Wang, Dmitrii Lebedev, Simeng Li, Sudharshan Rao, Kevin Wu, Lorcan Doyle, Kieran Wynne, Alfonso Blanco, Margaritha M. Mysior, Jeremy C. Simpson, Dimitri Scholz, Petra Wülfroth, Kai Zacharowski, Walter Kolch, Vadim Zhernovkov, Günther Eissner
Published 2025-06-01Get full text
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Inhibition of HDAC6 alters fumarate hydratase activity and mitochondrial structure by Andrew Roe, Catríona M. Dowling, Cian D’Arcy, Daniel Alencar Rodrigues, Yu Wang, Matthew Hiller, Carl Keogh, Kate E. R. Hollinshead, Massimiliano Garre, Brenton Cavanagh, Kieran Wynne, Tianyan Liu, Zhixing Chen, Emma Kerr, Marie McIlroy, Jochen H. M. Prehn, Ingmar Schoen, Tríona Ní Chonghaile
Published 2025-07-01Get full text
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