The TyphiNET data visualisation dashboard: unlocking Salmonella Typhi genomics data to support public health by Zoe A. Dyson, Louise Cerdeira, Vandana Sharma, Megan E. Carey, Kathryn E. Holt, Global Typhoid Genomics Consortium

Get full text

A Salmonella Typhimurium-Typhi genomic chimera: a model to study Vi polysaccharide capsule function in vivo. by Angela M Jansen, Lindsay J Hall, Simon Clare, David Goulding, Kathryn E Holt, Andrew J Grant, Piero Mastroeni, Gordon Dougan, Robert A Kingsley

Get full text

Determining genotype and antimicrobial resistance of Salmonella Typhi in environmental samples by amplicon sequencing by Catherine Troman, Samuel T. Horsfield, Dilip Abraham, Venkata Raghava Mohan, Sidhartha Giri, Satheesh Nair, Alexander G. Shaw, Zoe Dyson, Kathryn E. Holt, Nicholas C. Grassly

Get full text

Determining genotype and antimicrobial resistance of Salmonella Typhi in environmental samples by amplicon sequencing. by Catherine Troman, Samuel T Horsfield, Dilip Abraham, Venkata Raghava Mohan, Sidhartha Giri, Satheesh Nair, Alexander G Shaw, Zoe Dyson, Kathryn E Holt, Nicholas C Grassly

Get full text

Tools and challenges in the use of routine clinical data for antimicrobial resistance surveillance by Kathryn E. Holt, Megan E. Carey, Clare Chandler, James H. Cross, Zoe A. Dyson, Nicholas Furnham, Rebecca E. Glover, Mollie Virgo, Gwenan M. Knight

Get full text

Targeted sequencing of Enterobacterales bacteria using CRISPR-Cas9 enrichment and Oxford Nanopore Technologies by Hugh Cottingham, Louise M. Judd, Jessica A. Wisniewski, Ryan R. Wick, Thomas D. Stanton, Ben Vezina, Nenad Macesic, Anton Y. Peleg, Iruka N. Okeke, Kathryn E. Holt, Jane Hawkey

Get full text

Genomic and functional analysis of rmp locus variants in Klebsiella pneumoniae by Margaret M. C. Lam, Stephen M. Salisbury, Logan P. Treat, Ryan R. Wick, Louise M. Judd, Kelly L. Wyres, Sylvain Brisse, Kimberly A. Walker, Virginia L. Miller, Kathryn E. Holt

Get full text

Klebsiella pneumoniae with capsule type K64 is overrepresented among invasive disease in Vietnam [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Bich Vu Thi Ngoc, Kathryn E Holt, Dung Vu Tien Viet, Trinh Dao Tuyet, Sylvain Brisse, Heiman F L Wertheim, Diep Nguyen Thi Ngoc, Huong Tran Thi Kieu, Trung Nguyen Vu, H Rogier van Doorn

Get full text

The characterization of Klebsiella pneumoniae associated with neonatal sepsis in low- and middle-income countries to inform vaccine design by Francesca Nonne, Mariagrazia Molfetta, Gianina Florentina Belciug, Martina Carducci, Virginia Cianchi, Casey Zakroff, Salvatore Durante, Caroline Zellmer, Stephen Baker, Thomas D. Stanton, Kathryn E. Holt, Kelly Wyres, Neil Ravenscroft, Gianmarco Gasperini, Omar Rossi, Carlo Giannelli, Francesco Berlanda Scorza, Francesca Micoli

Get full text

The Molecular and Spatial Epidemiology of Typhoid Fever in Rural Cambodia. by Duy Pham Thanh, Corinne N Thompson, Maia A Rabaa, Soeng Sona, Sun Sopheary, Varun Kumar, Catrin Moore, Nga Tran Vu Thieu, Lalith Wijedoru, Kathryn E Holt, Vanessa Wong, Derek Pickard, Guy E Thwaites, Nicholas Day, Gordon Dougan, Paul Turner, Christopher M Parry, Stephen Baker

Get full text

Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium. by Vanessa K Wong, Derek J Pickard, Lars Barquist, Karthikeyan Sivaraman, Andrew J Page, Peter J Hart, Mark J Arends, Kathryn E Holt, Leanne Kane, Lynda F Mottram, Louise Ellison, Ruben Bautista, Chris J McGee, Sally J Kay, Thomas M Wileman, Linda J Kenney, Calman A MacLennan, Robert A Kingsley, Gordon Dougan

Get full text

South Asia as a Reservoir for the Global Spread of Ciprofloxacin-Resistant Shigella sonnei: A Cross-Sectional Study. by Hao Chung The, Maia A Rabaa, Duy Pham Thanh, Niall De Lappe, Martin Cormican, Mary Valcanis, Benjamin P Howden, Sonam Wangchuk, Ladaporn Bodhidatta, Carl J Mason, To Nguyen Thi Nguyen, Duong Vu Thuy, Corinne N Thompson, Nguyen Phu Huong Lan, Phat Voong Vinh, Tuyen Ha Thanh, Paul Turner, Poda Sar, Guy Thwaites, Nicholas R Thomson, Kathryn E Holt, Stephen Baker

Get full text

A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlapping populations but few recent transmission events across reservoirs by Marit A. K. Hetland, Mia A. Winkler, Håkon P. Kaspersen, Fredrik Håkonsholm, Ragna-Johanne Bakksjø, Eva Bernhoff, Jose F. Delgado-Blas, Sylvain Brisse, Annapaula Correia, Aasmund Fostervold, Margaret M. C. Lam, Bjørn-Tore Lunestad, Nachiket P. Marathe, Niclas Raffelsberger, Ørjan Samuelsen, Marianne Sunde, Arnfinn Sundsfjord, Anne Margrete Urdahl, Ryan R. Wick, Iren H. Löhr, Kathryn E. Holt

Get full text

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa. by International Typhoid Consortium, Vanessa K Wong, Kathryn E Holt, Chinyere Okoro, Stephen Baker, Derek J Pickard, Florian Marks, Andrew J Page, Grace Olanipekun, Huda Munir, Roxanne Alter, Paul D Fey, Nicholas A Feasey, Francois-Xavier Weill, Simon Le Hello, Peter J Hart, Samuel Kariuki, Robert F Breiman, Melita A Gordon, Robert S Heyderman, Jan Jacobs, Octavie Lunguya, Chisomo Msefula, Calman A MacLennan, Karen H Keddy, Anthony M Smith, Robert S Onsare, Elizabeth De Pinna, Satheesh Nair, Ben Amos, Gordon Dougan, Stephen Obaro

Get full text

Interplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model by Philip M. Ashton, Leonardos Mageiros, James E. Meiring, Angeziwa Chunga-Chirambo, Farhana Khanam, Sabina Dongol, Happy Banda, Abhilasha Karkey, Lorena Preciado-Llanes, Helena Thomaides-Brears, Malick Gibani, Nazmul Hasan Rajib, Nazia Rahman, Prasanta Kumar Biswas, Md Amirul Islam Bhuiyan, Sally Kay, Kate Auger, Olivier Seret, Nicholas R. Thomson, Andrew J. Pollard, Stephen Baker, Buddha Basnyat, John D. Clemens, Christiane Dolecek, Sarah J. Dunstan, Gordon Dougan, Robert S. Heyderman, Virginia E. Pitzer, Firdausi Qadri, Melita A. Gordon, Kathryn E. Holt, Thomas C. Darton, STRATAA Study Group

Get full text