Personalized signaling models for personalized treatments by Julio Saez‐Rodriguez, Nils Blüthgen

Get full text

RIDDEN: Data-driven inference of receptor activity from transcriptomic data. by Szilvia Barsi, Eszter Varga, Daniel Dimitrov, Julio Saez-Rodriguez, László Hunyady, Bence Szalai

Get full text

Data-driven reverse engineering of signaling pathways using ensembles of dynamic models. by David Henriques, Alejandro F Villaverde, Miguel Rocha, Julio Saez-Rodriguez, Julio R Banga

Get full text

Pan‐Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival by Abel Sousa, Aurelien Dugourd, Danish Memon, Borgthor Petursson, Evangelia Petsalaki, Julio Saez‐Rodriguez, Pedro Beltrao

Get full text

Learning tissue representation by identification of persistent local patterns in spatial omics data by Jovan Tanevski, Loan Vulliard, Miguel A. Ibarra-Arellano, Denis Schapiro, Felix J. Hartmann, Julio Saez-Rodriguez

Get full text

Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies by Federica Eduati, Patricia Jaaks, Jessica Wappler, Thorsten Cramer, Christoph A Merten, Mathew J Garnett, Julio Saez‐Rodriguez

Get full text

Systematic Analysis of Transcriptional and Post-transcriptional Regulation of Metabolism in Yeast. by Emanuel Gonçalves, Zrinka Raguz Nakic, Mattia Zampieri, Omar Wagih, David Ochoa, Uwe Sauer, Pedro Beltrao, Julio Saez-Rodriguez

Get full text

Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction by Julio Saez‐Rodriguez, Leonidas G Alexopoulos, Jonathan Epperlein, Regina Samaga, Douglas A Lauffenburger, Steffen Klamt, Peter K Sorger

Get full text

Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties. by Michael P Menden, Francesco Iorio, Mathew Garnett, Ultan McDermott, Cyril H Benes, Pedro J Ballester, Julio Saez-Rodriguez

Get full text

Mapping the human phosphatome on growth pathways by Francesca Sacco, Pier Federico Gherardini, Serena Paoluzi, Julio Saez‐Rodriguez, Manuela Helmer‐Citterich, Antonella Ragnini‐Wilson, Luisa Castagnoli, Gianni Cesareni

Get full text

Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data by Alexander Schäfer, Enio Gjerga, Richard WD Welford, Imke Renz, Francois Lehembre, Peter MA Groenen, Julio Saez‐Rodriguez, Ruedi Aebersold, Matthias Gstaiger

Get full text

Towards a rigorous assessment of systems biology models: the DREAM3 challenges. by Robert J Prill, Daniel Marbach, Julio Saez-Rodriguez, Peter K Sorger, Leonidas G Alexopoulos, Xiaowei Xue, Neil D Clarke, Gregoire Altan-Bonnet, Gustavo Stolovitzky

Get full text

WCN24-1863 Towards an IgA Nephropathy Atlas by Julio Saez-Rodriguez, Jon Barratt, Haresh Selvaskandan, Raphael Duivenvoorden, Matthias Kretzler, Laura Mariani, Celine Berthier, Anna Witsap, Hannes Olauson, Annika Wernerson, Loreto Gesualdo, Jenny Nyström

Get full text

Single‐cell biology: what does the future hold? by Maria Polychronidou, Jingyi Hou, M Madan Babu, Prisca Liberali, Ido Amit, Bart Deplancke, Galit Lahav, Shalev Itzkovitz, Matthias Mann, Julio Saez‐Rodriguez, Fabian Theis, Roland Eils

Get full text

Integrated intra‐ and intercellular signaling knowledge for multicellular omics analysis by Dénes Türei, Alberto Valdeolivas, Lejla Gul, Nicolàs Palacio‐Escat, Michal Klein, Olga Ivanova, Márton Ölbei, Attila Gábor, Fabian Theis, Dezső Módos, Tamás Korcsmáros, Julio Saez‐Rodriguez

Get full text

Phosphoproteomic analyses reveal novel cross‐modulation mechanisms between two signaling pathways in yeast by Stefania Vaga, Marti Bernardo‐Faura, Thomas Cokelaer, Alessio Maiolica, Christopher A Barnes, Ludovic C Gillet, Björn Hegemann, Frank van Drogen, Hoda Sharifian, Edda Klipp, Matthias Peter, Julio Saez‐Rodriguez, Ruedi Aebersold

Get full text

Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression by Nadine Tuechler, Mira Lea Burtscher, Martin Garrido-Rodriguez, Muzamil Majid Khan, Dénes Türei, Christian Tischer, Sarah Kaspar, Jennifer Jasmin Schwarz, Frank Stein, Mandy Rettel, Rafael Kramann, Mikhail M Savitski, Julio Saez-Rodriguez, Rainer Pepperkok

Get full text

Dysregulated mesenchymal PDGFR‐β drives kidney fibrosis by Eva M Buhl, Sonja Djudjaj, Barbara M Klinkhammer, Katja Ermert, Victor G Puelles, Maja T Lindenmeyer, Clemens D Cohen, Chaoyong He, Erawan Borkham‐Kamphorst, Ralf Weiskirchen, Bernd Denecke, Panuwat Trairatphisan, Julio Saez‐Rodriguez, Tobias B Huber, Lorin E Olson, Jürgen Floege, Peter Boor

Get full text

Publisher Correction: Comprehensive evaluation of phosphoproteomic-based kinase activity inference by Sophia Müller-Dott, Eric J. Jaehnig, Khoi Pham Munchic, Wen Jiang, Tomer M. Yaron-Barir, Sara R. Savage, Martin Garrido-Rodriguez, Jared L. Johnson, Alessandro Lussana, Evangelia Petsalaki, Jonathan T. Lei, Aurelien Dugourd, Karsten Krug, Lewis C. Cantley, D. R. Mani, Bing Zhang, Julio Saez-Rodriguez

Get full text

Comprehensive evaluation of phosphoproteomic-based kinase activity inference by Sophia Müller-Dott, Eric J. Jaehnig, Khoi Pham Munchic, Wen Jiang, Tomer M. Yaron-Barir, Sara R. Savage, Martin Garrido-Rodriguez, Jared L. Johnson, Alessandro Lussana, Evangelia Petsalaki, Jonathan T. Lei, Aurelien Dugourd, Karsten Krug, Lewis C. Cantley, D. R. Mani, Bing Zhang, Julio Saez-Rodriguez

Get full text