Julie Overbaugh
Julie M. Overbaugh is an American virologist. She is a professor at the Fred Hutchinson Cancer Research Center. Overbaugh is best known for her translational approach to studying HIV transmission and pathogenesis and studies of how the antibody response evolves to recognize viruses. Her work in maternal and infant HIV transmission helped make clear the risk posed by breastfeeding and highlighted unique characteristics of an infant immune response that could inform vaccine development. Major scientific contributions to the understanding of HIV transmission and pathogenesis also include: identifying a bottleneck that selects one or a few variants during HIV transmission; demonstrating the importance of female hormones in HIV infection risk; showing the HIV reinfection is common; demonstrating a role for antibodies that mediate ADCC in clinical disease; showing that HIV infected infants develop unique neutralizing antibody responses to HIV.Overbaugh is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences. In addition to being recognized for her scientific contributions, she is also recognized for her mentoring, her advocacy for equity and her commitment to global health. Provided by Wikipedia
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Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV. by Adam S Dingens, Priyamvada Acharya, Hugh K Haddox, Reda Rawi, Kai Xu, Gwo-Yu Chuang, Hui Wei, Baoshan Zhang, John R Mascola, Bridget Carragher, Clinton S Potter, Julie Overbaugh, Peter D Kwong, Jesse D Bloom
Published 2018-07-01Get full text
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The S2 subunit of spike encodes diverse targets for functional antibody responses to SARS-CoV-2. by Jamie Guenthoer, Meghan E Garrett, Michelle Lilly, Delphine M Depierreux, Felicitas Ruiz, Margaret Chi, Caitlin I Stoddard, Vrasha Chohan, Zak A Yaffe, Kevin Sung, Duncan Ralph, Helen Y Chu, Frederick A Matsen, Julie Overbaugh
Published 2024-08-01Get full text
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Delineating the functional activity of antibodies with cross-reactivity to SARS-CoV-2, SARS-CoV-1 and related sarbecoviruses. by Felicitas Ruiz, William B Foreman, Michelle Lilly, Viren A Baharani, Delphine M Depierreux, Vrasha Chohan, Ashley L Taylor, Jamie Guenthoer, Duncan Ralph, Frederick A Matsen Iv, Helen Y Chu, Paul D Bieniasz, Marceline Côté, Tyler N Starr, Julie Overbaugh
Published 2024-10-01Get full text
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Intact HIV DNA decays in children with and without complete viral load suppression. by Daniel B Reeves, Morgan Litchford, Carolyn S Fish, Anna Farrell-Sherman, Makayla Poindexter, Nashwa Ahmed, Noah A J Cassidy, Jillian Neary, Dalton Wamalwa, Agnes Langat, Daisy Chebet, Hellen Moraa, Annukka A R Antar, Jennifer Slyker, Sarah Benki-Nugent, Lillian B Cohn, Joshua T Schiffer, Julie Overbaugh, Grace John-Stewart, Dara A Lehman
Published 2025-04-01Get full text
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Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting. by Nicole A Doria-Rose, Han R Altae-Tran, Ryan S Roark, Stephen D Schmidt, Matthew S Sutton, Mark K Louder, Gwo-Yu Chuang, Robert T Bailer, Valerie Cortez, Rui Kong, Krisha McKee, Sijy O'Dell, Felicia Wang, Salim S Abdool Karim, James M Binley, Mark Connors, Barton F Haynes, Malcolm A Martin, David C Montefiori, Lynn Morris, Julie Overbaugh, Peter D Kwong, John R Mascola, Ivelin S Georgiev
Published 2017-01-01Get full text
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