Ethical and secure evidence generation from regionwide clinical data through a collaborative environment for advancing predictive care by Dolores Muñoyerro-Muñiz, Román Villegas, Víctor de la Oliva, Alberto Esteban-Medina, Patricia Fernández del Valle, Ana Sánchez, M. Belen Susin, Isidoro Gutierrez-Alvarez, Marta Reboredo, Laura Alejos, Carlos Loucera, Carlos Loucera, Joaquín Dopazo, Joaquín Dopazo

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The role of the interactome in the maintenance of deleterious variability in human populations by Luz Garcia‐Alonso, Jorge Jiménez‐Almazán, Jose Carbonell‐Caballero, Alicia Vela‐Boza, Javier Santoyo‐López, Guillermo Antiñolo, Joaquin Dopazo

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A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways. by Martín Garrido-Rodriguez, Daniel Lopez-Lopez, Francisco M Ortuno, María Peña-Chilet, Eduardo Muñoz, Marco A Calzado, Joaquin Dopazo

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First autochthonous transmission of West Nile virus (WNV) lineage 2 to humans in Spain by Maria Lara, Carlos S. Casimiro-Soriguer, Irene Pedrosa-Corral, Cristina Gómez-Camarasa, Nicola Lorusso, Jose M. Navarro-Marí, Joaquin Dopazo, Javier Perez-Florido, Sara Sanbonmatsu-Gámez

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A genomic strategy for precision medicine in rare diseases: integrating customized algorithms into clinical practice by Cristina Méndez-Vidal, Nereida Bravo-Gil, Javier Pérez-Florido, Irene Marcos-Luque, Raquel M. Fernández, José Luis Fernández-Rueda, María González-del Pozo, Marta Martín-Sánchez, Elena Fernández-Suárez, Marcela Mena, Rosario Carmona, Joaquín Dopazo, Salud Borrego, Guillermo Antiñolo

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Assessing COVID-19 Vaccine Effectiveness and Risk Factors for Severe Outcomes through Machine Learning Techniques: A Real-World Data Study in Andalusia, Spain by Álvaro Serrano-Ortiz, Juan Luis Romero-Cabrera, Jaime Monserrat Villatoro, Jaime Cordero-Ramos, Rafael Ruiz-Montero, Álvaro Ritoré, Joaquín Dopazo, Jorge del Diego Salas, Valle García Sánchez, Inmaculada Salcedo-Leal, Miguel Ángel Armengol de la Hoz, Isaac Túnez, Miguel Ángel Guzmán

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Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging by Alejandro Sola-García, María Ángeles Cáliz-Molina, Isabel Espadas, Michael Petr, Concepción Panadero-Morón, Daniel González-Morán, María Eugenia Martín-Vázquez, Álvaro Jesús Narbona-Pérez, Livia López-Noriega, Guillermo Martínez-Corrales, Raúl López-Fernández-Sobrino, Alejandro Castillo-Peña, Lina M. Carmona-Marin, Enrique Martínez-Force, Oscar Yanes, Maria Vinaixa, Daniel López-López, José Carlos Reyes, Joaquín Dopazo, Franz Martín, Benoit R. Gauthier, Morten Scheibye-Knudsen, Vivian Capilla-González, Alejandro Martín-Montalvo

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Cell‐to‐cell and type‐to‐type heterogeneity of signaling networks: insights from the crowd by Attila Gabor, Marco Tognetti, Alice Driessen, Jovan Tanevski, Baosen Guo, Wencai Cao, He Shen, Thomas Yu, Verena Chung, Single Cell Signaling in Breast Cancer DREAM Consortium members, Bernd Bodenmiller, Julio Saez‐Rodriguez, Augustinas Prusokas, Alidivinas Prusokas, Renata Retkute, Anand Rajasekar, Karthik Raman, Malvika Sudhakar, Raghunathan Rengaswamy, Edward S.C. Shih, Min‐jeong Kim, Changje Cho, Dohyang Kim, Hyeju Oh, Jinseub Hwang, Kim Jongtae, Yeongeun Nam, Sanghoo Yoon, Taeyong Kwon, Kyeongjun Lee, Sarika Chaudhary, Nehal Sharma, Shreya Bande, Gao Gao fan zhu Cankut Cubuk, Pelin Gundogdu, Joaquin Dopazo, Kinza Rian, Carlos Loucera, Matias M Falco, Martin Garrido‐Rodriguez, Maria Peña‐Chilet, Huiyuan Chen, Gabor Turu, Laszlo Hunyadi, Adam Misak, Baosen Guo, Wencai Cao, He Shen, Lisheng Zhou, Xiaoqing Jiang, Pieta Zhang, Aakansha Rai, Rintu Kutum, Sadhna Rana, Rajgopal Srinivasan, Swatantra Pradhan, James Li, Vladimir Bajic, Christophe Van Neste, Didier Barradas‐bautista, Somayah Abdullah Albarade, Igor Nikolskiy, Musalula Sinkala, Duc Tran, Hung Nguyen, Tin Nguyen, Alexander Wu, Benjamin DeMeo, Brian Hie, Rohit Singh, Jiwei Liu, Xueer Chen, Leonor Saiz, Jose M. G Vilar, Peng Qiu, Akash Gosain, Anjali Dhall, Dinesh Bajaj, Harpreet Kaur, Krishna Bagaria, Mayank Chauhan, Neelam Sharma, Gajendra Raghava, Sumeet Patiyal, Jianye Hao, Jiajie Peng, Shangyi Ning, Yi Ma, Zhongyu Wei, Atte Aalto, Jorge Goncalves, Laurent Mombaerts, Xinnan Dai, Jie Zheng, Piyushkumar Mundra, Fan Xu, Jie Wang, Krishna Kant Singh, Mingyu Lee

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COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms by Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta‐Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E Ackerman, Jason E Shoemaker, Jeremy Zucker, Kristie Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, Devasahayam Arokia Balaya Rex, Denise Slenter, Marvin Martens, Nhung Pham, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic‐Milacic, Andrea Senff-Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Varusai, Jean‐Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert W Overall, Dieter Maier, Angela Bauch, Benjamin M Gyori, John A Bachman, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban‐Medina, Maria Peña‐Chilet, Kinza Rian, Tomáš Helikar, Bhanwar Lal Puniya, Dezso Modos, Agatha Treveil, Marton Olbei, Bertrand De Meulder, Stephane Ballereau, Aurélien Dugourd, Aurélien Naldi, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C Freeman, Franck Augé, Jacques S Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon L Willighagen, Alexander R Pico, Chris T Evelo, Marc E Gillespie, Lincoln D Stein, Henning Hermjakob, Peter D'Eustachio, Julio Saez‐Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID‐19 Disease Map Community

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