Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like Mechanism by Natalia Fernández-Borges, Hasier Eraña, Saioa R. Elezgarai, Chafik Harrathi, Mayela Gayosso, Joaquín Castilla

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Accelerated high fidelity prion amplification within and across prion species barriers. by Kristi M Green, Joaquín Castilla, Tanya S Seward, Dana L Napier, Jean E Jewell, Claudio Soto, Glenn C Telling

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In vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoforms. by Pedro Fernandez-Funez, Sergio Casas-Tinto, Yan Zhang, Melisa Gómez-Velazquez, Marco A Morales-Garza, Ana C Cepeda-Nieto, Joaquín Castilla, Claudio Soto, Diego E Rincon-Limas

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Conservation of strain properties of bank vole-adapted chronic wasting disease in the absence of glycosylation and membrane anchoring by Enric Vidal, Hasier Eraña, Jorge M. Charco, Nuria L. Lorenzo, Samanta Giler, Montserrat Ordóñez, Eva Fernández-Muñoz, Maitena San-Juan-Ansoleaga, Glenn C. Telling, Manuel A. Sánchez-Martín, Mariví Geijo, Jesús R. Requena, Joaquín Castilla

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Susceptibility of European red deer (Cervus elaphus elaphus) to alimentary challenge with bovine spongiform encephalopathy. by Mark P Dagleish, Stuart Martin, Philip Steele, Jeanie Finlayson, Samantha L Eaton, Sílvia Sisó, Paula Stewart, Natalia Fernández-Borges, Scott Hamilton, Yvonne Pang, Francesca Chianini, Hugh W Reid, Wilfred Goldmann, Lorenzo González, Joaquín Castilla, Martin Jeffrey

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An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein. by Claudia Stincardini, Tania Massignan, Silvia Biggi, Saioa R Elezgarai, Valeria Sangiovanni, Ilaria Vanni, Michael Pancher, Valentina Adami, Jorge Moreno, Matteo Stravalaci, Giulia Maietta, Marco Gobbi, Alessandro Negro, Jesús R Requena, Joaquín Castilla, Romolo Nonno, Emiliano Biasini

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Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity by Carlos M. Díaz-Domínguez, Hasier Eraña, Francesca Peccati, Enric Vidal, Jorge M. Charco, Cristina Sampedro-Torres-Quevedo, Miguel A. Pérez-Castro, Nuria L. Lorenzo, Samanta Giler, Glenn C. Telling, Mariví Geijo, Jesús R. Requena, Gonzalo Jiménez-Osés, Joaquín Castilla

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Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease. by Ihssane Bouybayoune, Susanna Mantovani, Federico Del Gallo, Ilaria Bertani, Elena Restelli, Liliana Comerio, Laura Tapella, Francesca Baracchi, Natalia Fernández-Borges, Michela Mangieri, Cinzia Bisighini, Galina V Beznoussenko, Alessandra Paladini, Claudia Balducci, Edoardo Micotti, Gianluigi Forloni, Joaquín Castilla, Fabio Fiordaliso, Fabrizio Tagliavini, Luca Imeri, Roberto Chiesa

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Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions. by Miguel Ángel Pérez-Castro, Hasier Eraña, Enric Vidal, Jorge M Charco, Nuria L Lorenzo, Nuno Gonçalves-Anjo, Josu Galarza-Ahumada, Carlos M Díaz-Domínguez, Patricia Piñeiro, Ezequiel González-Miranda, Samanta Giler, Glenn Telling, Manuel A Sánchez-Martín, Joseba Garrido, Mariví Geijo, Jesús R Requena, Joaquín Castilla

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A comprehensive phylogeny of mammalian PRNP gene reveals no influence of prion misfolding propensity on the evolution of this gene. by Cristina Sampedro-Torres-Quevedo, Hasier Eraña, Jorge M Charco, Carlos M Díaz-Domínguez, Maitena San-Juan-Ansoleaga, Eva Fernández-Muñoz, Nuno Gonçalves-Anjo, Josu Galarza-Ahumada, Ana R Cortazar, Roberto F Nespolo, Julian F Quintero-Galvis, Africa Manero-Azua, Diego Polanco-Alonso, Adrián Gaite-Reguero, Íñigo Olalde, Urko M Marigorta, Guiomar Perez de Nanclares, Ana M Aransay, Joaquín Castilla

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