Editorial: Viral impact on CNS: mechanisms of immune dysfunction and cognitive decline by Thomas A. Angelovich, Thomas A. Angelovich, Thomas A. Angelovich, Sonia Mediouni, Robyn S. Klein, Jacob D. Estes, Jacob D. Estes, Bruce J. Brew, Bruce J. Brew, Melissa J. Churchill, Melissa J. Churchill, Melissa J. Churchill

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Neuroinflammation associated with proviral DNA persists in the brain of virally suppressed people with HIV by Sarah J. Byrnes, Janna Jamal Eddine, Jingling Zhou, Emily Chalmers, Emma Wanicek, Narin Osman, Trisha A. Jenkins, Michael Roche, Michael Roche, Bruce J. Brew, Bruce J. Brew, Jacob D. Estes, Jacob D. Estes, Thomas A. Angelovich, Thomas A. Angelovich, Thomas A. Angelovich, Melissa J. Churchill, Melissa J. Churchill, Melissa J. Churchill

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Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection. by Haiying Li, Laura E Richert-Spuhler, Tristan I Evans, Jacqueline Gillis, Michelle Connole, Jacob D Estes, Brandon F Keele, Nichole R Klatt, R Keith Reeves

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Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission. by Jeremy Smedley, Baris Turkbey, Marcelino L Bernardo, Gregory Q Del Prete, Jacob D Estes, Gary L Griffiths, Hisataka Kobayashi, Peter L Choyke, Jeffrey D Lifson, Brandon F Keele

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MRSA Infections in HIV-Infected People Are Associated with Decreased MRSA-Specific Th1 Immunity. by Netanya S Utay, Annelys Roque, J Katherina Timmer, David R Morcock, Claire DeLeage, Anoma Somasunderam, Amy C Weintrob, Brian K Agan, Jacob D Estes, Nancy F Crum-Cianflone, Daniel C Douek

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Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21. by Suresh Pallikkuth, Luca Micci, Zachary S Ende, Robin I Iriele, Barbara Cervasi, Benton Lawson, Colleen S McGary, Kenneth A Rogers, James G Else, Guido Silvestri, Kirk Easley, Jacob D Estes, Francois Villinger, Savita Pahwa, Mirko Paiardini

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Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration. by Irini Sereti, Jacob D Estes, William L Thompson, David R Morcock, Margaret A Fischl, Thérèse Croughs, Stéphanie Beq, Sylvie Lafaye de Micheaux, Michael D Yao, Alexander Ober, Eleanor M P Wilson, Ven Natarajan, Hiromi Imamichi, Mohamed R Boulassel, Michael M Lederman, Jean-Pierre Routy

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Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques. by Sarah J Byrnes, Kathleen Busman-Sahay, Thomas A Angelovich, Skyler Younger, Sol Taylor-Brill, Michael Nekorchuk, Stephen Bondoc, Rachel Dannay, Margaret Terry, Catherine R Cochrane, Trisha A Jenkins, Michael Roche, Claire Deleage, Steven E Bosinger, Mirko Paiardini, Bruce J Brew, Jacob D Estes, Melissa J Churchill

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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells. by Luca Micci, Xavier Alvarez, Robin I Iriele, Alexandra M Ortiz, Emily S Ryan, Colleen S McGary, Claire Deleage, Brigitte B McAtee, Tianyu He, Cristian Apetrei, Kirk Easley, Savita Pahwa, Ronald G Collman, Cynthia A Derdeyn, Miles P Davenport, Jacob D Estes, Guido Silvestri, Andrew A Lackner, Mirko Paiardini

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Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication. by Adam J Ericsen, Michael Lauck, Mariel S Mohns, Sarah R DiNapoli, James P Mutschler, Justin M Greene, Jason T Weinfurter, Gabrielle Lehrer-Brey, Trent M Prall, Samantha M Gieger, Connor R Buechler, Kristin A Crosno, Eric J Peterson, Matthew R Reynolds, Roger W Wiseman, Benjamin J Burwitz, Jacob D Estes, Jonah B Sacha, Thomas C Friedrich, Jason M Brenchley, David H O'Connor

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Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. by Rachele M Bochart, Kathleen Busman-Sahay, Stephen Bondoc, David W Morrow, Alexandra M Ortiz, Christine M Fennessey, Miranda B Fischer, Oriene Shiel, Tonya Swanson, Christine M Shriver-Munsch, Hugh B Crank, Kimberly M Armantrout, Aaron M Barber-Axthelm, Charlotte Langner, Cassandra R Moats, Caralyn S Labriola, Rhonda MacAllister, Michael K Axthelm, Jason M Brenchley, Brandon F Keele, Jacob D Estes, Scott G Hansen, Jeremy V Smedley

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Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence. by Benjamin Varco-Merth, Morgan Chaunzwa, Derick M Duell, Alejandra Marenco, William Goodwin, Rachel Dannay, Michael Nekorchuk, Danica Shao, Kathleen Busman-Sahay, Christine M Fennessey, Lorna Silipino, Michael Hull, William J Bosche, Randy Fast, Kelli Oswald, Rebecca Shoemaker, Rachele Bochart, Rhonda MacAllister, Caralyn S Labriola, Jeremy V Smedley, Michael K Axthelm, Miles P Davenport, Paul T Edlefsen, Jacob D Estes, Brandon F Keele, Jeffrey D Lifson, Sharon R Lewin, Louis J Picker, Afam A Okoye

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