The interactions of Lipoprotein(a) with common cardiovascular risk factors in cardiovascular disease risk: evidence based on the UK Biobank by Linjun Ao, Raymond Noordam, J Wouter Jukema, Diana van Heemst, Ko Willems van Dijk

Get full text

Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease by Linjun Ao, Diana van Heemst, J. Wouter Jukema, Patrick C.N. Rensen, Ko Willems van Dijk, Raymond Noordam

Get full text

Defibrillation Threshold Testing After ICD Implantation in Patients with Chronic Kidney Disease by Rohit J. Timal, Lano Osman, Joris I. Rotmans, Marianne Bootsma, Bart Mertens, Martin J. Schalij, Ton J. Rabelink, J. Wouter Jukema

Get full text

Epicardial fat tissue, a hidden enemy against the early recovery of left ventricular systolic function after transcatheter aortic valve implantation by Helen S. Anwar, Pilar Lopez Santi, Magdy Algowhary, Mohamed Aboel-Kassem F. Abdelmegid, Hatem A. Helmy, J. Wouter Jukema, Nina Ajmone Marsan, Frank Van Der Kley

Get full text

Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis by José A. Inia, Anita van Nieuwkoop-van Straalen, J. Wouter Jukema, Bidda Rolin, Ellen Marie Staarup, Christina K. Mogensen, Hans M.G. Princen, Anita M. van den Hoek

Get full text

Left Ventricular Diastolic Dysfunction in Dialysis Patients Assessed by Novel Speckle Tracking Strain Rate Analysis: Prevalence and Determinants by Mihály K. de Bie, Nina Ajmone Marsan, André Gaasbeek, Jeroen J. Bax, Marc Groeneveld, Bas A. Gabreels, Victoria Delgado, Ton J. Rabelink, Martin J. Schalij, J. Wouter Jukema

Get full text

Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population Study. by Rakesh S Birjmohun, Menno Vergeer, Erik S G Stroes, Manjinder S Sandhu, Sally L Ricketts, Michael W Tanck, Nicholas J Wareham, J Wouter Jukema, John J P Kastelein, Kay-Tee Khaw, S Matthijs Boekholdt

Get full text

Association of indexed aortic dimensions with the presence and extent of coronary artery ectasia in patients with acute coronary syndrome by Martijn J.H. van Oort, Federico Oliveri, Florens W.J. de Lange, Madelien V. Regeer, B.O. Bingen, J.Wouter Jukema, Frank van der Kley, Ibtihal Al Amri, Jose M. Montero-Cabezas

Get full text

Blood pressure variability and cardiovascular risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). by Rosalinde K E Poortvliet, Ian Ford, Suzanne M Lloyd, Naveed Sattar, Simon P Mooijaart, Anton J M de Craen, Rudi G J Westendorp, J Wouter Jukema, Christopher J Packard, Jacobijn Gussekloo, Wouter de Ruijter, David J Stott

Get full text

Long-term effects of statin treatment in elderly people: extended follow-up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). by Suzanne M Lloyd, David J Stott, Anton J M de Craen, Patricia M Kearney, Naveed Sattar, Ivan Perry, Christopher J Packard, Andrew Briggs, Laura Marchbank, Harry Comber, J Wouter Jukema, Rudi G J Westendorp, Stella Trompet, Brendan M Buckley, Ian Ford

Get full text

Effect of sodium-glucose cotransporter 2 inhibitors on ventricular function in systemic right ventricular failure by Lorna Swan, Gruschen R Veldtman, Hubert W Vliegen, Philippine Kiès, Filip Zemrak, Amanda Hunter, Anastasia D Egorova, Monique RM Jongbloed, J Wouter Jukema, Simon T MacDonald, Niki L Walker, Ali N Zaidi, Madelien V Regeer, Bart JA Mertens, Ralph ML Neijenhuis, Ari M Cedars

Get full text

Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality by Stella Trompet, Douwe Pons, Sandip M. Kanse, Anton J. M. de Craen, M. Arfan Ikram, Jeffrey J. W. Verschuren, Aeilko H. Zwinderman, Pieter A. F. M. Doevendans, René A. Tio, Robbert J. de Winter, P. Eline Slagboom, Rudi G. J. Westendorp, J. Wouter Jukema

Get full text

Intravascular lithotripsy for the treatment of calcified coronary lesions in individuals of advanced age: a post-hoc analysis of the multicentre, prospective BENELUX-IVL studyResea... by Federico Oliveri, Pablo Valentín García, Martijn J.H. van Oort, Akshay Phagu, Ibtihal Al Amri, Brian O. Bingen, Valeria Paradies, Gianluca Mincione, Bimmer E. Claessen, Aukelien C. Dimitriu-Leen, Joelle Kefer, Hany Girgis, Tessel Vossenberg, Alessandro Mandurino-Mirizzi, Frank Van der Kley, J. Wouter Jukema, José M. Montero-Cabezas

Get full text

Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. by Joshua C Bis, Colleen Sitlani, Ryan Irvin, Christy L Avery, Albert Vernon Smith, Fangui Sun, Daniel S Evans, Solomon K Musani, Xiaohui Li, Stella Trompet, Bouwe P Krijthe, Tamara B Harris, P Miguel Quibrera, Jennifer A Brody, Serkalem Demissie, Barry R Davis, Kerri L Wiggins, Gregory J Tranah, Leslie A Lange, Nona Sotoodehnia, David J Stott, Oscar H Franco, Lenore J Launer, Til Stürmer, Kent D Taylor, L Adrienne Cupples, John H Eckfeldt, Nicholas L Smith, Yongmei Liu, James G Wilson, Susan R Heckbert, Brendan M Buckley, M Arfan Ikram, Eric Boerwinkle, Yii-Der Ida Chen, Anton J M de Craen, Andre G Uitterlinden, Jerome I Rotter, Ian Ford, Albert Hofman, Naveed Sattar, P Eline Slagboom, Rudi G J Westendorp, Vilmundur Gudnason, Ramachandran S Vasan, Thomas Lumley, Steven R Cummings, Herman A Taylor, Wendy Post, J Wouter Jukema, Bruno H Stricker, Eric A Whitsel, Bruce M Psaty, Donna Arnett

Get full text

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. by J Gustav Smith, Janine F Felix, Alanna C Morrison, Andreas Kalogeropoulos, Stella Trompet, Jemma B Wilk, Olof Gidlöf, Xinchen Wang, Michael Morley, Michael Mendelson, Roby Joehanes, Symen Ligthart, Xiaoyin Shan, Joshua C Bis, Ying A Wang, Marketa Sjögren, Julius Ngwa, Jeffrey Brandimarto, David J Stott, David Aguilar, Kenneth M Rice, Howard D Sesso, Serkalem Demissie, Brendan M Buckley, Kent D Taylor, Ian Ford, Chen Yao, Chunyu Liu, CHARGE-SCD consortium, EchoGen consortium, QT-IGC consortium, CHARGE-QRS consortium, Nona Sotoodehnia, Pim van der Harst, Bruno H Ch Stricker, Stephen B Kritchevsky, Yongmei Liu, J Michael Gaziano, Albert Hofman, Christine S Moravec, André G Uitterlinden, Manolis Kellis, Joyce B van Meurs, Kenneth B Margulies, Abbas Dehghan, Daniel Levy, Björn Olde, Bruce M Psaty, L Adrienne Cupples, J Wouter Jukema, Luc Djousse, Oscar H Franco, Eric Boerwinkle, Laurie A Boyer, Christopher Newton-Cheh, Javed Butler, Ramachandran S Vasan, Thomas P Cappola, Nicholas L Smith

Get full text

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers. by Amy E Taylor, Richard W Morris, Meg E Fluharty, Johan H Bjorngaard, Bjørn Olav Åsvold, Maiken E Gabrielsen, Archie Campbell, Riccardo Marioni, Meena Kumari, Jenni Hällfors, Satu Männistö, Pedro Marques-Vidal, Marika Kaakinen, Alana Cavadino, Iris Postmus, Lise Lotte N Husemoen, Tea Skaaby, Tarunveer S Ahluwalia, Jorien L Treur, Gonneke Willemsen, Caroline Dale, S Goya Wannamethee, Jari Lahti, Aarno Palotie, Katri Räikkönen, Aliaksei Kisialiou, Alex McConnachie, Sandosh Padmanabhan, Andrew Wong, Christine Dalgård, Lavinia Paternoster, Yoav Ben-Shlomo, Jessica Tyrrell, John Horwood, David M Fergusson, Martin A Kennedy, Tim Frayling, Ellen A Nohr, Lene Christiansen, Kirsten Ohm Kyvik, Diana Kuh, Graham Watt, Johan Eriksson, Peter H Whincup, Jacqueline M Vink, Dorret I Boomsma, George Davey Smith, Debbie Lawlor, Allan Linneberg, Ian Ford, J Wouter Jukema, Christine Power, Elina Hyppönen, Marjo-Riitta Jarvelin, Martin Preisig, Katja Borodulin, Jaakko Kaprio, Mika Kivimaki, Blair H Smith, Caroline Hayward, Pål R Romundstad, Thorkild I A Sørensen, Marcus R Munafò, Naveed Sattar

Get full text

Genome‐Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants by William J. Young, Peter J. van der Most, Traci M. Bartz, Maxime M. Bos, Ginevra Biino, ThuyVy Duong, Luisa Foco, Jesus T. Lominchar, Martina Müller‐Nurasyid, Giuseppe Giovanni Nardone, Alessandro Pecori, Julia Ramirez, Linda Repetto, Katharina Schramm, Xia Shen, Stefan van Duijvenboden, Diana van Heemst, Stefan Weiss, Jie Yao, Jan‐Walter Benjamins, Alvaro Alonso, Beatrice Spedicati, Mary L. Biggs, Jennifer A. Brody, Marcus Dörr, Christian Fuchsberger, Martin Gögele, Xiuqing Guo, M. Arfan Ikram, J. Wouter Jukema, Stefan Kääb, Jørgen K. Kanters, Henry J. Lin, Allan Linneberg, Matthias Nauck, Ilja M. Nolte, Giulia Pianigiani, Aurora Santin, Elsayed Z. Soliman, Paola Tesolin, Simona Vaccargiu, Melanie Waldenberger, Pim van der Harst, Niek Verweij, Dan E. Arking, Maria Pina Concas, Alessandro De Grandi, Giorgia Girotto, Niels Grarup, Maryam Kavousi, Dennis O. Mook‐Kanamori, Pau Navarro, Michele Orini, Sandosh Padmanabhan, Cristian Pattaro, Annette Peters, Mario Pirastu, Peter P. Pramstaller, Susan R. Heckbert, Mortiz Sinner, Harold Snieder, Uwe Völker, James F. Wilson, W. James Gauderman, Pier D. Lambiase, Nona Sotoodehnia, Andrew Tinker, Helen R. Warren, Raymond Noordam, Patricia B. Munroe

Get full text

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. by Jens Baumert, Jie Huang, Barbara McKnight, Maria Sabater-Lleal, Maristella Steri, Audrey Y Chu, Stella Trompet, Lorna M Lopez, Myriam Fornage, Alexander Teumer, Weihong Tang, Alicja R Rudnicka, Anders Mälarstig, Jouke-Jan Hottenga, Maryam Kavousi, Jari Lahti, Toshiko Tanaka, Caroline Hayward, Jennifer E Huffman, Pierre-Emmanuel Morange, Lynda M Rose, Saonli Basu, Ann Rumley, David J Stott, Brendan M Buckley, Anton J M de Craen, Serena Sanna, Marco Masala, Reiner Biffar, Georg Homuth, Angela Silveira, Bengt Sennblad, Anuj Goel, Hugh Watkins, Martina Müller-Nurasyid, Regina Rückerl, Kent Taylor, Ming-Huei Chen, Eco J C de Geus, Albert Hofman, Jacqueline C M Witteman, Moniek P M de Maat, Aarno Palotie, Gail Davies, David S Siscovick, Ivana Kolcic, Sarah H Wild, Jaejoon Song, Wendy L McArdle, Ian Ford, Naveed Sattar, David Schlessinger, Anne Grotevendt, Maria Grazia Franzosi, Thomas Illig, Melanie Waldenberger, Thomas Lumley, Geoffrey H Tofler, Gonneke Willemsen, André G Uitterlinden, Fernando Rivadeneira, Katri Räikkönen, Daniel I Chasman, Aaron R Folsom, Gordon D Lowe, Rudi G J Westendorp, P Eline Slagboom, Francesco Cucca, Henri Wallaschofski, Rona J Strawbridge, Udo Seedorf, Wolfgang Koenig, Joshua C Bis, Kenneth J Mukamal, Jenny van Dongen, Elisabeth Widen, Oscar H Franco, John M Starr, Kiang Liu, Luigi Ferrucci, Ozren Polasek, James F Wilson, Tiphaine Oudot-Mellakh, Harry Campbell, Pau Navarro, Stefania Bandinelli, Johan Eriksson, Dorret I Boomsma, Abbas Dehghan, Robert Clarke, Anders Hamsten, Eric Boerwinkle, J Wouter Jukema, Silvia Naitza, Paul M Ridker, Henry Völzke, Ian J Deary, Alexander P Reiner, David-Alexandre Trégouët, Christopher J O'Donnell, David P Strachan, Annette Peters, Nicholas L Smith

Get full text

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. by Eleonora Porcu, Marco Medici, Giorgio Pistis, Claudia B Volpato, Scott G Wilson, Anne R Cappola, Steffan D Bos, Joris Deelen, Martin den Heijer, Rachel M Freathy, Jari Lahti, Chunyu Liu, Lorna M Lopez, Ilja M Nolte, Jeffrey R O'Connell, Toshiko Tanaka, Stella Trompet, Alice Arnold, Stefania Bandinelli, Marian Beekman, Stefan Böhringer, Suzanne J Brown, Brendan M Buckley, Clara Camaschella, Anton J M de Craen, Gail Davies, Marieke C H de Visser, Ian Ford, Tom Forsen, Timothy M Frayling, Laura Fugazzola, Martin Gögele, Andrew T Hattersley, Ad R Hermus, Albert Hofman, Jeanine J Houwing-Duistermaat, Richard A Jensen, Eero Kajantie, Margreet Kloppenburg, Ee M Lim, Corrado Masciullo, Stefano Mariotti, Cosetta Minelli, Braxton D Mitchell, Ramaiah Nagaraja, Romana T Netea-Maier, Aarno Palotie, Luca Persani, Maria G Piras, Bruce M Psaty, Katri Räikkönen, J Brent Richards, Fernando Rivadeneira, Cinzia Sala, Mona M Sabra, Naveed Sattar, Beverley M Shields, Nicole Soranzo, John M Starr, David J Stott, Fred C G J Sweep, Gianluca Usala, Melanie M van der Klauw, Diana van Heemst, Alies van Mullem, Sita H Vermeulen, W Edward Visser, John P Walsh, Rudi G J Westendorp, Elisabeth Widen, Guangju Zhai, Francesco Cucca, Ian J Deary, Johan G Eriksson, Luigi Ferrucci, Caroline S Fox, J Wouter Jukema, Lambertus A Kiemeney, Peter P Pramstaller, David Schlessinger, Alan R Shuldiner, Eline P Slagboom, André G Uitterlinden, Bijay Vaidya, Theo J Visser, Bruce H R Wolffenbuttel, Ingrid Meulenbelt, Jerome I Rotter, Tim D Spector, Andrew A Hicks, Daniela Toniolo, Serena Sanna, Robin P Peeters, Silvia Naitza

Get full text

Genome-wide association and functional follow-up reveals new loci for kidney function. by Cristian Pattaro, Anna Köttgen, Alexander Teumer, Maija Garnaas, Carsten A Böger, Christian Fuchsberger, Matthias Olden, Ming-Huei Chen, Adrienne Tin, Daniel Taliun, Man Li, Xiaoyi Gao, Mathias Gorski, Qiong Yang, Claudia Hundertmark, Meredith C Foster, Conall M O'Seaghdha, Nicole Glazer, Aaron Isaacs, Ching-Ti Liu, Albert V Smith, Jeffrey R O'Connell, Maksim Struchalin, Toshiko Tanaka, Guo Li, Andrew D Johnson, Hinco J Gierman, Mary Feitosa, Shih-Jen Hwang, Elizabeth J Atkinson, Kurt Lohman, Marilyn C Cornelis, Åsa Johansson, Anke Tönjes, Abbas Dehghan, Vincent Chouraki, Elizabeth G Holliday, Rossella Sorice, Zoltan Kutalik, Terho Lehtimäki, Tõnu Esko, Harshal Deshmukh, Sheila Ulivi, Audrey Y Chu, Federico Murgia, Stella Trompet, Medea Imboden, Barbara Kollerits, Giorgio Pistis, CARDIoGRAM Consortium, ICBP Consortium, CARe Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), Tamara B Harris, Lenore J Launer, Thor Aspelund, Gudny Eiriksdottir, Braxton D Mitchell, Eric Boerwinkle, Helena Schmidt, Margherita Cavalieri, Madhumathi Rao, Frank B Hu, Ayse Demirkan, Ben A Oostra, Mariza de Andrade, Stephen T Turner, Jingzhong Ding, Jeanette S Andrews, Barry I Freedman, Wolfgang Koenig, Thomas Illig, Angela Döring, H-Erich Wichmann, Ivana Kolcic, Tatijana Zemunik, Mladen Boban, Cosetta Minelli, Heather E Wheeler, Wilmar Igl, Ghazal Zaboli, Sarah H Wild, Alan F Wright, Harry Campbell, David Ellinghaus, Ute Nöthlings, Gunnar Jacobs, Reiner Biffar, Karlhans Endlich, Florian Ernst, Georg Homuth, Heyo K Kroemer, Matthias Nauck, Sylvia Stracke, Uwe Völker, Henry Völzke, Peter Kovacs, Michael Stumvoll, Reedik Mägi, Albert Hofman, Andre G Uitterlinden, Fernando Rivadeneira, Yurii S Aulchenko, Ozren Polasek, Nick Hastie, Veronique Vitart, Catherine Helmer, Jie Jin Wang, Daniela Ruggiero, Sven Bergmann, Mika Kähönen, Jorma Viikari, Tiit Nikopensius, Michael Province, Shamika Ketkar, Helen Colhoun, Alex Doney, Antonietta Robino, Franco Giulianini, Bernhard K Krämer, Laura Portas, Ian Ford, Brendan M Buckley, Martin Adam, Gian-Andri Thun, Bernhard Paulweber, Margot Haun, Cinzia Sala, Marie Metzger, Paul Mitchell, Marina Ciullo, Stuart K Kim, Peter Vollenweider, Olli Raitakari, Andres Metspalu, Colin Palmer, Paolo Gasparini, Mario Pirastu, J Wouter Jukema, Nicole M Probst-Hensch, Florian Kronenberg, Daniela Toniolo, Vilmundur Gudnason, Alan R Shuldiner, Josef Coresh, Reinhold Schmidt, Luigi Ferrucci, David S Siscovick, Cornelia M van Duijn, Ingrid Borecki, Sharon L R Kardia, Yongmei Liu, Gary C Curhan, Igor Rudan, Ulf Gyllensten, James F Wilson, Andre Franke, Peter P Pramstaller, Rainer Rettig, Inga Prokopenko, Jacqueline C M Witteman, Caroline Hayward, Paul Ridker, Afshin Parsa, Murielle Bochud, Iris M Heid, Wolfram Goessling, Daniel I Chasman, W H Linda Kao, Caroline S Fox

Get full text