Enhancing polygenic scores for cardiometabolic traits through tissue- and cell-type-specific functional annotations by Kristjan Norland, Daniel J. Schaid, Iftikhar J. Kullo

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Transformer patient embedding using electronic health records enables patient stratification and progression analysis by Su Xian, Monika E. Grabowska, Iftikhar J. Kullo, Yuan Luo, Jordan W. Smoller, Theresa L. Walunas, Wei-Qi Wei, Gail P. Jarvik, Sean D. Mooney, David R. Crosslin

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Phenome-wide association study identifies multiple traits associated with a polygenic risk score for colorectal cancer by Elisabeth A. Rosenthal, Wei-Qi Wei, Yuan Luo, Bahram Namjou-Khales, Daniel J. Schaid, Edward D. Esplin, Michael Lape, Leah Kottyan, Jennifer Allen Pacheco, Chunhua Weng, Adam Samuel Gordon, Iftikhar J. Kullo, David R. Crosslin, William M. Grady, Li Hsu, Ulrike Peters, Gail P. Jarvik

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Promise and Peril of a Genotype‐First Approach to Mendelian Cardiovascular Disease by Babken Asatryan, Brittney Murray, Rafik Tadros, Marina Rieder, Ravi A. Shah, Ghaith Sharaf Dabbagh, Andrew P. Landstrom, Stephan Dobner, Patricia B. Munroe, Christopher M. Haggerty, Argelia Medeiros‐Domingo, Anjali T. Owens, Iftikhar J. Kullo, Christopher Semsarian, Tobias Reichlin, Andreas S. Barth, Dan M. Roden, Cynthia A. James, James S. Ware, C. Anwar A. Chahal

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Risk factors affecting polygenic score performance across diverse cohorts by Daniel Hui, Scott Dudek, Krzysztof Kiryluk, Theresa L Walunas, Iftikhar J Kullo, Wei-Qi Wei, Hemant Tiwari, Josh F Peterson, Wendy K Chung, Brittney H Davis, Atlas Khan, Leah C Kottyan, Nita A Limdi, Qiping Feng, Megan J Puckelwartz, Chunhua Weng, Johanna L Smith, Elizabeth W Karlson, Regeneron Genetics Center, Penn Medicine BioBank, Gail P Jarvik, Marylyn D Ritchie

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Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data. by Jonathan D Mosley, Sara L Van Driest, Emma K Larkin, Peter E Weeke, John S Witte, Quinn S Wells, Jason H Karnes, Yan Guo, Lisa Bastarache, Lana M Olson, Catherine A McCarty, Jennifer A Pacheco, Gail P Jarvik, David S Carrell, Eric B Larson, David R Crosslin, Iftikhar J Kullo, Gerard Tromp, Helena Kuivaniemi, David J Carey, Marylyn D Ritchie, Josh C Denny, Dan M Roden

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Genome-wide study of resistant hypertension identified from electronic health records. by Logan Dumitrescu, Marylyn D Ritchie, Joshua C Denny, Nihal M El Rouby, Caitrin W McDonough, Yuki Bradford, Andrea H Ramirez, Suzette J Bielinski, Melissa A Basford, High Seng Chai, Peggy Peissig, David Carrell, Jyotishman Pathak, Luke V Rasmussen, Xiaoming Wang, Jennifer A Pacheco, Abel N Kho, M Geoffrey Hayes, Martha Matsumoto, Maureen E Smith, Rongling Li, Rhonda M Cooper-DeHoff, Iftikhar J Kullo, Christopher G Chute, Rex L Chisholm, Gail P Jarvik, Eric B Larson, David Carey, Catherine A McCarty, Marc S Williams, Dan M Roden, Erwin Bottinger, Julie A Johnson, Mariza de Andrade, Dana C Crawford

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