Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells. by Younis M Khan, Paul Kirkham, Peter J Barnes, Ian M Adcock

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Exosomes and Exosomal miRNA in Respiratory Diseases by Shamila D. Alipoor, Esmaeil Mortaz, Johan Garssen, Masoud Movassaghi, Mehdi Mirsaeidi, Ian M. Adcock

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Increased eosinophils after oral corticosteroid treatment for asthma exacerbation correlated with longer ER stays and persisting thymic stromal lymphopoietin and increased Park2 by Kittipong Maneechotesuwan, Jirawat Assawabhumi, Jirabhorn Chankham, Kanda Kasetsinsombat, Khin Su Su Htwe, Ian M. Adcock

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Probiotics in the Management of Lung Diseases by Esmaeil Mortaz, Ian M. Adcock, Gert Folkerts, Peter J. Barnes, Arjan Paul Vos, Johan Garssen

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Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease. by Kittipong Maneechotesuwan, Xin Yao, Kazuhiro Ito, Elen Jazrawi, Omar S Usmani, Ian M Adcock, Peter J Barnes

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Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1. by Hannu Kankaanranta, Pinja Ilmarinen, Xianzhi Zhang, Ian M Adcock, Aleksi Lahti, Peter J Barnes, Mark A Giembycz, Mark A Lindsay, Eeva Moilanen

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BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production. by John E S Park, Dongmin Shao, Paul D Upton, Patricia Desouza, Ian M Adcock, Rachel J Davies, Nicholas W Morrell, Mark J D Griffiths, Stephen J Wort

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Immune response to Mycobacterium tuberculosis infection in the parietal pleura of patients with tuberculous pleurisy. by Gaetano Caramori, Lisa Lasagna, Angelo G Casalini, Ian M Adcock, Paolo Casolari, Marco Contoli, Federica Tafuro, Anna Padovani, Kian Fan Chung, Peter J Barnes, Alberto Papi, Guido Rindi, Giuseppina Bertorelli

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Cigarette smoke induced airway inflammation is independent of NF-κB signalling. by Joseph M D Rastrick, Christopher S Stevenson, Suffwan Eltom, Megan Grace, Meirion Davies, Iain Kilty, Steven M Evans, Manolis Pasparakis, Matthew C Catley, Toby Lawrence, Ian M Adcock, Maria G Belvisi, Mark A Birrell

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Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension. by Laura C Price, Gaetano Caramori, Frederic Perros, Chao Meng, Natalia Gambaryan, Peter Dorfmuller, David Montani, Paolo Casolari, Jie Zhu, Konstantinos Dimopoulos, Dongmin Shao, Barbara Girerd, Sharon Mumby, Alastair Proudfoot, Mark Griffiths, Alberto Papi, Marc Humbert, Ian M Adcock, S John Wort

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The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD. by Kirsty E Russell, Kian Fan Chung, Colin J Clarke, Andrew L Durham, Patrick Mallia, Joseph Footitt, Sebastian L Johnston, Peter J Barnes, Simon R Hall, Karen D Simpson, Malcolm R Starkey, Philip M Hansbro, Ian M Adcock, Coen H Wiegman

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Neutrophilic inflammation in sputum or blood does not define a clinically distinct asthma phenotype in ATLANTIS by Pauline J.M. Kuks, Tessa M. Kole, Monica Kraft, Salman Siddiqui, Leonardo M. Fabbri, Klaus F. Rabe, Alberto Papi, Chris Brightling, Dave Singh, Thys van der Molen, Jan Willem W.H. Kocks, Kian Fan Chung, Ian M. Adcock, Pankaj K. Bhavsar, Nazanin Zounemat Kermani, Irene H. Heijink, Simon D. Pouwels, Huib A.M. Kerstjens, Dirk-Jan Slebos, Maarten van den Berge

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Clinical importance of patient-reported outcome measures in severe asthma: results from U-BIOPRED by Roy Meys, Frits M.E. Franssen, Alex J. Van ‘t Hul, Per S. Bakke, Massimo Caruso, Barbro Dahlén, Stephen J. Fowler, Thomas Geiser, Peter H. Howarth, Ildikó Horváth, Norbert Krug, Annelie F. Behndig, Florian Singer, Jacek Musial, Dominick E. Shaw, Paolo Montuschi, Anke H. Maitland-van der Zee, Peter J. Sterk, Graham Roberts, Nazanin Z. Kermani, Raffaele A. Incalzi, Renaud Louis, Lars I. Andersson, Scott S. Wagers, Sven-Erik Dahlén, Kian Fan Chung, Ian M. Adcock, Martijn A. Spruit, on behalf of the U-BIOPRED Study Group

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Chromosome 21 variants tied to severe asthma exacerbations: A genome-wide association study in a Brazilian population by Maria B.R. de Santana, PhD, Álvaro A. Cruz, MD, Helena M.P. Teixeira, PhD, Hatilla dos S. Silva, MSc, Mahmoud I. Abdel-Aziz, PhD, Simone Hashimoto, MD, Susanne J.H. Vijverberg, PhD, Esther Herrera-Luis, PhD, Maria Pino-Yanes, PhD, Esteban G. Burchard, PhD, Kian Fan Chung, MD, Ratko Djukanovic, MD, Sven-Erik Dahlén, MD, Ian M. Adcock, PhD, Corey Cox, MD, Tonya Brunetti, PhD, Monica Campbell, MS, Nicholas Rafaels, Kathleen C. Barnes, PhD, Anke H. Maitland-van der Zee, PhD, Camila A. Figueiredo, PhD, Ryan S. Costa, PhD

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Serum and urine eosinophil-derived neurotoxin (EDN) levels predict biologic response in severe asthma by Yu Ri Kang, MD, Hyunkyoung Kim, MS, MPH, Chae Eun Lee, BS, Jae-Woo Jung, MD, PhD, Ji-Yong Moon, MD, PhD, So Young Park, MD, MS, Sae-Hoon Kim, MD, PhD, Min-Suk Yang, MD, PhD, Byung Keun Kim, MD, PhD, Jae-Woo Kwon, MD, PhD, Hye-Kyung Park, MD, PhD, Young-Hee Nam, MD, PhD, Young-Joo Cho, MD, PhD, Taehoon Lee, MD, PhD, Ian M. Adcock, MD, PhD, Pank Bhavsar, MD, PhD, Kian Fan Chung, MD, PhD, Tae-Bum Kim, MD, PhD

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