Natural killer cell subpopulations in the peripheral blood of single ventricle/hypoplastic left heart syndrome patients via single-cell RNA sequencing by Hui-Qi Qu, Kushagra Goel, Kayleigh Ostberg, Diana J. Slater, Fengxiang Wang, James Snyder, Cuiping Hou, Garnet Eister, John J. Connolly, Michael March, Joseph T. Glessner, Joseph T. Glessner, Joseph T. Glessner, Charlly Kao, Hakon Hakonarson, Hakon Hakonarson, Hakon Hakonarson, Hakon Hakonarson, Hakon Hakonarson

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Role of genetic modifiers on pulmonary consequences of cancer therapy in children by Shoshana Leftin Dobkin, Xiao Chang, Frank Mentch, Hakon Hakonarson

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Data-informed insights into sex differences in peripheral blood mononuclear cells from single-cell transcriptomics by Hui-Qi Qu, Joseph T. Glessner, Charlly Kao, Hakon Hakonarson

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The impact of prematurity on pediatric asthma morbidity and indices with environmental pollution and genetic susceptibility by Jelte Kelchtermans, Frank Mentch, Huiqi Qu, Sharon A. McGrath-Morrow, Hakon Hakonarson

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Exploring the Therapeutic Potential for Breast Cancer of Phytochemicals and Secondary Metabolites in Marjoram, Thyme, and Persimmon by Aubrey Mattingly, Zoe Vickery, Diana Ivankovic, Christopher L. Farrell, Hakon Hakonarson, Katie Nguyen, Luigi Boccuto

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Sex-specific spirometry effects of adult COPD polygenic score in children with asthma by Jelte Kelchtermans, Joseph M. Collaco, Huiqi Qu, Frank Mentch, Sharon A. McGrath-Morrow, Hakon Hakonarson

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GDF15 is a heart‐derived hormone that regulates body growth by Ting Wang, Jian Liu, Caitlin McDonald, Katherine Lupino, Xiandun Zhai, Benjamin J Wilkins, Hakon Hakonarson, Liming Pei

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O57: Association of polygenic risk scores with disease prevalence in pediatrics: Insights into obesity, asthma, type 1 and type 2 diabetes by Margaret Harr, Priyanka Maripuri, Huiqi Qu, Haijun Qiu, Shannon Terek, Jasmine Purcell, Sam McCreary, Ciani Graham, John Connolly, Hakon Hakonarson

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The International Health Cohorts Consortium (IHCC) advances population health research and genomic discovery by John J. Connolly, Scott Sundseth, Grant M. Wood, Chisom Nwaneri, Geoffrey Ginsburg, Philip Awadalla, Michele Ramsay, Thomas Keane, Peter Goodhand, Adam S. Butterworth, Hakon Hakonarson

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Mendelian randomization analysis of plasma levels of CD209 and MICB proteins and the risk of varicose veins of lower extremities. by Alexandra S Shadrina, Elizaveta E Elgaeva, Ian B Stanaway, Gail P Jarvik, Bahram Namjou, Wei-Qi Wei, Joe Glessner, Hakon Hakonarson, Pradeep Suri, Yakov A Tsepilov

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DNA methylation differences stratified by normalized fetal/placental weight ratios suggest neurodevelopmental deficits in neonates with congenital heart disease. by Marin Jacobwitz, Michael Xie, Jamie Catalano, Ingo Helbig, J William Gaynor, Nancy Burnham, Rebecca L Linn, Juliana Gebb, Mark W Russell, Hakon Hakonarson, Barbara H Chaiyachati, Ana G Cristancho

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DNA methylation differences stratified by normalized fetal/placental weight ratios suggest neurodevelopmental deficits in neonates with congenital heart disease by Marin Jacobwitz, Michael Xie, Jamie Catalano, Ingo Helbig, J. William Gaynor, Nancy Burnham, Rebecca L. Linn, Juliana Gebb, Mark W. Russell, Hakon Hakonarson, Barbara H. Chaiyachati, Ana G. Cristancho

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Multi-trait genetic analysis of asthma and eosinophils uncovers pleiotropic loci in East Asians by Lili Zhi, Qiwen Zheng, Yue Jiang, Lu Yu, Linzehao Li, Yingchao Song, Bichen Peng, Chumeng Zhang, Hengxuan Jiang, Ren Li, Frank Mentch, Joseph Glessner, Peilin Jia, Hua Tang, Hakon Hakonarson, Xiao Chang

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Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma. by Lee D McDaniel, Karina L Conkrite, Xiao Chang, Mario Capasso, Zalman Vaksman, Derek A Oldridge, Anna Zachariou, Millicent Horn, Maura Diamond, Cuiping Hou, Achille Iolascon, Hakon Hakonarson, Nazneen Rahman, Marcella Devoto, Sharon J Diskin

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The knockout of Moesin leads to excess microglia-mediated synaptic pruning and impairs social novelty in a mouse model by Wanjing Lai, Junlin Chen, Hongyao Zhu, Yunbo Jiang, Yimei Niu, Qingpei Chen, Zhihua Luo, Yu Hu, Li Fang, Yaxuan Wang, Youqiang Song, Charlly Kao, Jubao Duan, Kwok-Fai So, Hakon Hakonarson, Li Zhang, Kai Wang, Lingling Shi

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Copy number variations in alternative splicing gene networks impact lifespan. by Joseph T Glessner, Albert Vernon Smith, Saarene Panossian, Cecilia E Kim, Nagahide Takahashi, Kelly A Thomas, Fengxiang Wang, Kallyn Seidler, Tamara B Harris, Lenore J Launer, Brendan Keating, John Connolly, Patrick M A Sleiman, Joseph D Buxbaum, Struan F A Grant, Vilmundur Gudnason, Hakon Hakonarson

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A framework for conducting GWAS using repeated measures data with an application to childhood BMI by Kimberley Burrows, Anni Heiskala, Jonathan P. Bradfield, Zhanna Balkhiyarova, Lijiao Ning, Mathilde Boissel, Yee-Ming Chan, Philippe Froguel, Amelie Bonnefond, Hakon Hakonarson, Alexessander Couto Alves, Deborah A. Lawlor, Marika Kaakinen, Marjo-Riitta Järvelin, Struan F. A. Grant, Kate Tilling, Inga Prokopenko, Sylvain Sebert, Mickaël Canouil, Nicole M. Warrington

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Novel EDGE encoding method enhances ability to identify genetic interactions. by Molly A Hall, John Wallace, Anastasia M Lucas, Yuki Bradford, Shefali S Verma, Bertram Müller-Myhsok, Kristin Passero, Jiayan Zhou, John McGuigan, Beibei Jiang, Sarah A Pendergrass, Yanfei Zhang, Peggy Peissig, Murray Brilliant, Patrick Sleiman, Hakon Hakonarson, John B Harley, Krzysztof Kiryluk, Kristel Van Steen, Jason H Moore, Marylyn D Ritchie

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Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis by Meritxell Oliva, Mrinal K. Sarkar, Michael E. March, Amir Hossein Saeidian, Frank D. Mentch, Chen-Lin Hsieh, Fanying Tang, Ranjitha Uppala, Matthew T. Patrick, Qinmengge Li, Rachael Bogle, J. Michelle Kahlenberg, Deborah Watson, Joseph T. Glessner, Leila Youssefian, Hassan Vahidnezhad, Lam C. Tsoi, Hakon Hakonarson, Johann E. Gudjonsson, Kathleen M. Smith, Bridget Riley-Gillis

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Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy. by Ulrike Esslinger, Sophie Garnier, Agathe Korniat, Carole Proust, Georgios Kararigas, Martina Müller-Nurasyid, Jean-Philippe Empana, Michael P Morley, Claire Perret, Klaus Stark, Alexander G Bick, Sanjay K Prasad, Jennifer Kriebel, Jin Li, Laurence Tiret, Konstantin Strauch, Declan P O'Regan, Kenneth B Marguiles, Jonathan G Seidman, Pierre Boutouyrie, Patrick Lacolley, Xavier Jouven, Christian Hengstenberg, Michel Komajda, Hakon Hakonarson, Richard Isnard, Eloisa Arbustini, Harald Grallert, Stuart A Cook, Christine E Seidman, Vera Regitz-Zagrosek, Thomas P Cappola, Philippe Charron, François Cambien, Eric Villard

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