Prior human endemic coronavirus exposure does not affect humoral responses to SARS-CoV-2 protein vaccines by Guy de Bruyn, Haritha Adhikarla, Caroline K. Brackett, Yichen Jia, Premkumar Lakshmanane, Sarah V. Mudrak, Sheetal Sawant, Donghui Zhang, Roman M. Chicz, Saranya Sridhar, Georgia D. Tomaras, Kelly E. Seaton

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GeM-LR: Discovering predictive biomarkers for small datasets in vaccine studies. by Lin Lin, Rachel L Spreng, Kelly E Seaton, S Moses Dennison, Lindsay C Dahora, Daniel J Schuster, Sheetal Sawant, Peter B Gilbert, Youyi Fong, Neville Kisalu, Andrew J Pollard, Georgia D Tomaras, Jia Li

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Optimizing human B cell repertoire analyses to interpret clinical data and design sequential HIV vaccines by Milton Maciel, Lindsey R. Baden, Brian Briney, Nicole A. Doria-Rose, Kasalina N. Kiwanuka, Shelly J. Krebs, Angela Malaspina, Georgia D. Tomaras, Andrew Ward, Gunilla B. Karlsson Hedestam, Wilton B. Williams, M. Patricia D’Souza

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A Pentavalent HIV-1 Subtype C Vaccine Containing Computationally Selected gp120 Strains Improves the Breadth of V1V2 Region Responses by Xiaoying Shen, Bette Korber, Rachel L. Spreng, Sheetal S. Sawant, Allan deCamp, Arthur S. McMillan, Ryan Mathura, Susan Zolla-Pazner, Abraham Pinter, Robert Parks, Cindy Bowman, Laura Sutherland, Richard Scearce, Nicole L. Yates, David C. Montefiori, Barton F. Haynes, Georgia D. Tomaras

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Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses. by Matthew Zirui Tay, Pinghuang Liu, LaTonya D Williams, Michael D McRaven, Sheetal Sawant, Thaddeus C Gurley, Thomas T Xu, S Moses Dennison, Hua-Xin Liao, Agnès-Laurence Chenine, S Munir Alam, M Anthony Moody, Thomas J Hope, Barton F Haynes, Georgia D Tomaras

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Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses. by Gemma Hancock, Hongbing Yang, Elisabeth Yorke, Emma Wainwright, Victoria Bourne, Alyse Frisbee, Tamika L Payne, Mark Berrong, Guido Ferrari, Denis Chopera, Tomas Hanke, Beatriz Mothe, Christian Brander, M Juliana McElrath, Andrew McMichael, Nilu Goonetilleke, Georgia D Tomaras, Nicole Frahm, Lucy Dorrell

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Non-HIV Vaccine-Induced Immune Responses as Potential Baseline Immunogenicity Predictors of ALVAC-HIV and AIDSVAX B/E-Induced Immune Responses by Ying Huang, Shomoita Alam, Erica Andersen-Nissen, Lindsay N. Carpp, One B. Dintwe, Britta S. Flach, Nicole Grunenberg, Fatima Laher, Stephen C. De Rosa, Guido Ferrari, Craig Innes, Linda-Gail Bekker, James G. Kublin, M. Juliana McElrath, Georgia D. Tomaras, Glenda E. Gray, Peter B. Gilbert

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Innate immune signatures to a partially-efficacious HIV vaccine predict correlates of HIV-1 infection risk. by Erica Andersen-Nissen, Andrew Fiore-Gartland, Lamar Ballweber Fleming, Lindsay N Carpp, Anneta F Naidoo, Michael S Harper, Valentin Voillet, Nicole Grunenberg, Fatima Laher, Craig Innes, Linda-Gail Bekker, James G Kublin, Ying Huang, Guido Ferrari, Georgia D Tomaras, Glenda Gray, Peter B Gilbert, M Juliana McElrath

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Sequential Immunization with gp140 Boosts Immune Responses Primed by Modified Vaccinia Ankara or DNA in HIV-Uninfected South African Participants. by Gavin Churchyard, Koleka Mlisana, Shelly Karuna, Anna-Lise Williamson, Carolyn Williamson, Lynn Morris, Georgia D Tomaras, Stephen C De Rosa, Peter B Gilbert, Niya Gu, Chenchen Yu, Nonhlanhla N Mkhize, Tandile Hermanus, Mary Allen, Michael Pensiero, Susan W Barnett, Glenda Gray, Linda-Gail Bekker, David C Montefiori, James Kublin, Lawrence Corey

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DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques. by Rashmi Jalah, Viraj Kulkarni, Vainav Patel, Margherita Rosati, Candido Alicea, Jenifer Bear, Lei Yu, Yongjun Guan, Xiaoying Shen, Georgia D Tomaras, Celia LaBranche, David C Montefiori, Rajasekhar Prattipati, Abraham Pinter, Julian Bess, Jeffrey D Lifson, Steven G Reed, Niranjan Y Sardesai, David J Venzon, Antonio Valentin, George N Pavlakis, Barbara K Felber

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Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study. by Catherine A Cosgrove, Charles J Lacey, Alethea V Cope, Angela Bartolf, Georgina Morris, Celine Yan, Susan Baden, Tom Cole, Darrick Carter, Elizabeth Brodnicki, Xiaoying Shen, Sarah Joseph, Stephen C DeRosa, Lili Peng, Xuesong Yu, Guido Ferrari, Mike Seaman, David C Montefiori, Nicole Frahm, Georgia D Tomaras, Wolfgang Stöhr, Sheena McCormack, Robin J Shattock

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Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection. by Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K P Liu, Emma L Turnbull, Jesus F Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D Tomaras, Barton F Haynes, Clive M Gray, Persephone Borrow, Mario Roederer, Andrew J McMichael, Kent J Weinhold

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Antibody Fab‐Fc properties outperform titer in predictive models of SIV vaccine‐induced protection by Srivamshi Pittala, Kenneth Bagley, Jennifer A Schwartz, Eric P Brown, Joshua A Weiner, Ilia J Prado, Wenlei Zhang, Rong Xu, Ayuko Ota‐Setlik, Ranajit Pal, Xiaoying Shen, Charles Beck, Guido Ferrari, George K Lewis, Celia C LaBranche, David C Montefiori, Georgia D Tomaras, Galit Alter, Mario Roederer, Timothy R Fouts, Margaret E Ackerman, Chris Bailey‐Kellogg

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Retrospective analysis of sex-disaggregated immune responses to ALVAC-HIV and bivalent subtype C gp120/MF59 HIV vaccines by Cassie G. Ackerley, Srilatha Edupuganti, Chenchen Yu, Alison C. Roxby, Kelly E. Seaton, Linda-Gail Bekker, Mary Allen, Stephen C. DeRosa, Nicole L. Yates, Jack Heptinstall, Nonhlanhla N. Mkhize, Mookho Malahleha, Kathryn Mngadi, Brodie Daniels, Craig Innes, Briana D. Furch, Marguerite Koutsoukos, Guido Ferrari, Lynn Morris, David C. Montefiori, M. Juliana McElrath, Georgia D. Tomaras, Fatima Laher, Zoe Moodie

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Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. by Fangping Cai, Wei-Hung Chen, Weimin Wu, Julia A Jones, Misook Choe, Neelakshi Gohain, Xiaoying Shen, Celia LaBranche, Amanda Eaton, Laura Sutherland, Esther M Lee, Giovanna E Hernandez, Nelson R Wu, Richard Scearce, Michael S Seaman, M Anthony Moody, Sampa Santra, Kevin Wiehe, Georgia D Tomaras, Kshitij Wagh, Bette Korber, Mattia Bonsignori, David C Montefiori, Barton F Haynes, Natalia de Val, M Gordon Joyce, Kevin O Saunders

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Distinct immune responses in people living with HIV following SARS-CoV-2 recovery by Dieter Mielke, Shuying Sue Li, Daniel J. Schuster, Xiaohong Li, Jiani Hu, Shelly Karuna, Kelly E. Seaton, Caroline Brackett, Brooke Dunn, Taylor Keyes, Adam Zalaquett, Sherry Stanfield-Oakley, Lu Zhang, Martina S. Wesley, Nathan Eisel, Nicole L. Yates, Xiaoying Shen, Lakshmanane Premkumar, Russell St. Germain, Anton M. Sholukh, Kristen Cohen, Stephen de Rosa, April Kaur Randhawa, John A. Hural, Lawrence Corey, M. Julianna McElrath, Georgia D. Tomaras, Ollivier Hyrien, Guido Ferrari

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Computationally Selected Multivalent HIV-1 Subtype C Vaccine Protects Against Heterologous SHIV Challenge by Dieter Mielke, Marina Tuyishime, Natasha S. Kelkar, Yunfei Wang, Robert Parks, Sampa Santra, Wes Rountree, LaTonya D. Williams, Tiffany Peters, Nathan Eisel, Sheetal Sawant, Lu Zhang, Derrick Goodman, Shalini Jha, Adam Zalaquett, Pratamesh Ramasubramanian, Sherry Stanfield-Oakley, Gary Matyas, Zoltan Beck, Mangala Rao, Julie Ake, Thomas N. Denny, David C. Montefiori, Margaret E. Ackerman, Lawrence Corey, Georgia D. Tomaras, Bette T. Korber, Barton F. Haynes, Xiaoying Shen, Guido Ferrari

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Safety and immunogenicity after a 30-month boost of a subtype C ALVAC-HIV (vCP2438) vaccine prime plus bivalent subtype C gp120/MF59 vaccine boost (HVTN 100): A phase 1-2 randomize... by Vimla Naicker, Fatima Laher, Linda-Gail Bekker, Kelly E Seaton, Mary Allen, Stephen De Rosa, Nicole L Yates, Nonhlanhla N Mkhize, Kevin Saunders, Jack Heptinstall, Mookho Malahleha, Kathryn Mngadi, Brodie Daniels, Craig Innes, Chenchen Yu, Tandile Modise, Valerie Bekker, Nicole Grunenberg, Briana Furch, Maurine D Miner, Sanjay Phogat, Carlos A Diazgranados, Sanjay Gurunathan, Marguerite Koutsoukos, Olivier Van Der Meeren, Alison C Roxby, Guido Ferrari, Lynn Morris, David Montefiori, M Juliana McElrath, Georgia D Tomaras, Zoe Moodie

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Loss of HIV candidate vaccine efficacy in male macaques by mucosal nanoparticle immunization rescued by V2-specific response by Mohammad Arif Rahman, Massimiliano Bissa, Hanna Scinto, Savannah E. Howe, Sarkis Sarkis, Zhong-Min Ma, Anna Gutowska, Xunqing Jiang, Christina C. Luo, Luca Schifanella, Ramona Moles, Isabela Silva de Castro, Shraddha Basu, Kombo F. N’guessan, LaTonya D. Williams, Manuel Becerra-Flores, Melvin N. Doster, Tanya Hoang, Hyoyoung Choo-Wosoba, Emmanuel Woode, Yongjun Sui, Georgia D. Tomaras, Dominic Paquin-Proulx, Mangala Rao, James D. Talton, Xiang-Peng Kong, Susan Zolla-Pazner, Timothy Cardozo, Genoveffa Franchini, Jay A. Berzofsky

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A polyvalent DNA prime with matched polyvalent protein/GLA-SE boost regimen elicited the most robust and broad IgG and IgG3 V1V2 binding antibody and CD4+ T cell responses among 13... by Zoe Moodie, Shuying Sue Li, Elena E. Giorgi, LaTonya D. Williams, One Dintwe, Lindsay N. Carpp, Shiyu Chen, Kelly E. Seaton, Sheetal S. Sawant, Lu Zhang, Jack Heptinstall, Shuying Liu, Nicole Grunenberg, Frank Tomaka, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Julie A. Ake, Sandhya Vasan, Giuseppe Pantaleo, Ian Frank, Lindsey R. Baden, Paul A. Goepfert, Michael Keefer, Mike Chirenje, Mina C. Hosseinipour, Kathryn Mngadi, Fatima Laher, Nigel Garrett, Linda-Gail Bekker, Stephen De Rosa, Erica Andersen-Nissen, James G. Kublin, Shan Lu, Peter B. Gilbert, Glenda E. Gray, Lawrence Corey, M. Juliana McElrath, Georgia D. Tomaras

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