Geoffrey L. Smith

Geoffrey Lilley Smith (born 1955) is a British virologist and medical research authority in the area of Vaccinia virus and the family of Poxviruses. Since 1 October 2011 he is head of the Department of Pathology at the University of Cambridge and a principal research fellow of the Wellcome Trust. Before that, he was head of the Department of Virology at Imperial College London. Provided by Wikipedia
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  1. 1
    Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2.

    Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2. by Jennifer H Stuart, Rebecca P Sumner, Yongxu Lu, Joseph S Snowden, Geoffrey L Smith

    Published 2016-12-01
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  2. 2
    Inhibition of IkappaB kinase by vaccinia virus virulence factor B14.

    Inhibition of IkappaB kinase by vaccinia virus virulence factor B14. by Ron A-J Chen, Grigory Ryzhakov, Samantha Cooray, Felix Randow, Geoffrey L Smith

    Published 2008-02-01
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  3. 3
    Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence.

    Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence. by Pavla Strnadova, Hongwei Ren, Robert Valentine, Michela Mazzon, Trevor R Sweeney, Ian Brierley, Geoffrey L Smith

    Published 2015-09-01
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  4. 4
    Vaccinia protein F12 has structural similarity to kinesin light chain and contains a motor binding motif required for virion export.

    Vaccinia protein F12 has structural similarity to kinesin light chain and contains a motor binding motif required for virion export. by Gareth W Morgan, Michael Hollinshead, Brian J Ferguson, Brendan J Murphy, David C J Carpentier, Geoffrey L Smith

    Published 2010-02-01
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  5. 5
    The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling.

    The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling. by Alice A Torres, Stephanie L Macilwee, Amir Rashid, Sarah E Cox, Jonas D Albarnaz, Claudio A Bonjardim, Geoffrey L Smith

    Published 2022-02-01
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  6. 6
    Selective modulation of cell surface proteins during vaccinia infection: A resource for identifying viral immune evasion strategies.

    Selective modulation of cell surface proteins during vaccinia infection: A resource for identifying viral immune evasion strategies. by Delphine M Depierreux, Arwen F Altenburg, Lior Soday, Alice Fletcher-Etherington, Robin Antrobus, Brian J Ferguson, Michael P Weekes, Geoffrey L Smith

    Published 2022-06-01
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  7. 7
    Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7.

    Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7. by Leonie Unterholzner, Rebecca P Sumner, Marcin Baran, Hongwei Ren, Daniel S Mansur, Nollaig M Bourke, Felix Randow, Geoffrey L Smith, Andrew G Bowie

    Published 2011-09-01
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  8. 8
    A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus.

    A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus. by Nicholas E Peters, Nicholas E Peters, Brian J Ferguson, Michela Mazzon, Aodhnait S Fahy, Ewelina Krysztofinska, Raquel Arribas-Bosacoma, Laurence H Pearl, Hongwei Ren, Geoffrey L Smith

    Published 2013-01-01
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  9. 9
    Structure and function of A41, a vaccinia virus chemokine binding protein.

    Structure and function of A41, a vaccinia virus chemokine binding protein. by Mohammad W Bahar, Julia C Kenyon, Mike M Putz, Nicola G A Abrescia, James E Pease, Emma L Wise, David I Stuart, Geoffrey L Smith, Jonathan M Grimes

    Published 2008-01-01
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  10. 10
    Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence.

    Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence. by Carlos Maluquer de Motes, Samantha Cooray, Hongwei Ren, Gabriel M F Almeida, Kieran McGourty, Mohammad W Bahar, David I Stuart, Jonathan M Grimes, Stephen C Graham, Geoffrey L Smith

    Published 2011-12-01
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  11. 11
    Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis.

    Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis. by Stephen C Graham, Mohammad W Bahar, Samantha Cooray, Ron A-J Chen, Daniel M Whalen, Nicola G A Abrescia, David Alderton, Raymond J Owens, David I Stuart, Geoffrey L Smith, Jonathan M Grimes

    Published 2008-08-01
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  12. 12
    The nuclear localization signal of monkeypox virus protein P2 orthologue is critical for inhibition of IRF3-mediated innate immunity

    The nuclear localization signal of monkeypox virus protein P2 orthologue is critical for inhibition of IRF3-mediated innate immunity by Pengtao Jiao, Jianing Ma, Yuna Zhao, Xiaoxiao Jia, Haoran Zhang, Wenhui Fan, Xiaojuan Jia, Xiaoyuan Bai, Yiqi Zhao, Yongxu Lu, He Zhang, Jiayin Guo, Gang Pang, Ke Zhang, Min Fang, Minghua Li, Wenjun Liu, Geoffrey L. Smith, Lei Sun

    Published 2024-12-01
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  13. 13
    T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination

    T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination by Ji-Li Chen, Beibei Wang, Yongxu Lu, Elie Antoun, Olivia Bird, Philip G. Drennan, Zixi Yin, Guihai Liu, Xuan Yao, Maya Pidoux, Adam Bates, Deshni Jayathilaka, Junyuan Wang, Brian Angus, Sally Beer, Alexis Espinosa, J. Kenneth Baillie, Malcolm G. Semple, ISARIC4C Investigators, Timothy Rostron, Craig Waugh, Paul Sopp, Julian C. Knight, James N. Fullerton, Mark Coles, Geoffrey L. Smith, Alexander J. Mentzer, Yanchun Peng, Tao Dong

    Published 2025-05-01
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