Deep normative modelling reveals insights into early-stage Alzheimer's disease using multi-modal neuroimaging data by Ana Lawry Aguila, Luigi Lorenzini, Mohammed Janahi, Frederik Barkhof, Andre Altmann

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Picture: A web application for decision support in glioma surgery by Maisa N.G. van Genderen, Raymond M. Martens, Frederik Barkhof, Philip C. de Witt Hamer, Roelant S. Eijgelaar

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Structured reporting of gliomas based on VASARI criteria to improve report content and consistency by Olivia Goodkin, Jiaming Wu, Hugh Pemberton, Ferran Prados, Sjoerd B. Vos, Stefanie Thust, John Thornton, Tarek Yousry, Sotirios Bisdas, Frederik Barkhof

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Regional cerebellar atrophy related to disability and cognitive progression in multiple sclerosis by Myrte Strik, Iris Dekker, Aurélie Ruet, Hanneke E. Hulst, Mike P. Wattjes, Frederik Barkhof, Bernard M.J. Uitdehaag, Joep Killestein, Menno M. Schoonheim

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Validation of a semi-automated method to quantify lesion volume changes in multiple sclerosis on 2D proton-density-weighted scans based on image subtraction by Rozemarijn M. Mattiesing, Serena Stel, Alysha S. Mangroe, Iman Brouwer, Adriaan Versteeg, Ronald A. van Schijndel, Bernard M.J. Uitdehaag, Frederik Barkhof, Hugo Vrenken, Joost P.A. Kuijer

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An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis by Ermelinda De Meo, Ferran Prados Carrasco, J. William L. Brown, Alasdair J. Coles, Nick G. Cunniffe, Amy E. Jolly, Baris Kanber, Rebecca Samson, Frederik Barkhof, Declan Chard

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Individualized lesion-symptom mapping using explainable artificial intelligence for the cognitive impact of white matter hyperintensities by Ryanne Offenberg, Alberto De Luca, Geert Jan Biessels, Frederik Barkhof, Wiesje M. van der Flier, Argonde C. van Harten, Ewoud van der Lelij, Josien Pluim, Hugo Kuijf

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Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification by Sophie E. Mastenbroek, Lyduine E. Collij, Jacob W. Vogel, Serena Caldera, Geidy E. Serrano, Charles H. Adler, Claudia Marina Vargiu, Sebastian Palmqvist, Frederik Barkhof, Piero Parchi, Thomas G. Beach, Rik Ossenkoppele, Oskar Hansson

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Improving criteria for dissemination in space in multiple sclerosis by including additional regions by Michael A. Foster, Giuseppe Pontillo, Indran Davagnanam, Sara Collorone, Ferran Prados, Baris Kanber, Marios C. Yiannakas, Lola Ogunbowale, Ailbhe Burke, Claudia A. M. Gandini Wheeler‐Kingshott, Olga Ciccarelli, Wallace Brownlee, Frederik Barkhof, Ahmed T. Toosy

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Clinical and mechanistic effects of cladribine in relapsing multiple sclerosis: 2-year results from the MAGNIFY-MS Study by Klaus Schmierer, Heinz Wiendl, Frederik Barkhof, Xavier Montalban, Anat Achiron, Tobias Derfuss, Andrew Chan, Suzanne Hodgkinson, Alexandre Prat, Letizia Leocani, Finn Sellebjerg, Patrick Vermersch, Hulin Jin, Laura Sponton, Anita Chudecka, Lidia Gardner, Nicola De Stefano

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Exploring effects of Souvenaid on cerebral glucose metabolism in Alzheimer's disease by Nienke M.E. Scheltens, Casper T. Briels, Maqsood Yaqub, Frederik Barkhof, Ronald Boellaard, Wiesje M. van derFlier, Lothar A. Schwarte, Charlotte E. Teunissen, Amos Attali, Laus M. Broersen, Bart N.M. vanBerckel, Philip Scheltens

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Scanner-specific optimisation of automated lesion segmentation in MS by David R. van Nederpelt, Giuseppe Pontillo, Mar Barrantes-Cepas, Iman Brouwer, Eva M.M. Strijbis, Menno M. Schoonheim, Bastiaan Moraal, Bas Jasperse, Henk-Jan M.M. Mutsaerts, Joep Killestein, Frederik Barkhof, Joost P.A. Kuijer, Hugo Vrenken

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Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic acc... by Hanneke F M Rhodius-Meester, Ingrid S van Maurik, Juha Koikkalainen, Antti Tolonen, Kristian S Frederiksen, Steen G Hasselbalch, Hilkka Soininen, Sanna-Kaisa Herukka, Anne M Remes, Charlotte E Teunissen, Frederik Barkhof, Yolande A L Pijnenburg, Philip Scheltens, Jyrki Lötjönen, Wiesje M van der Flier

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CHIT1 and DDAH1 levels relate to amyloid-related imaging abnormalities risk profile in Alzheimer’s disease patients by Marlies Oosthoek, Everard G.B. Vijverberg, Elena R. Blujdea, Sjors G.J.G. In’t Veld, Martín Pucheu Avilés, Sára E. Zsadanyi, Yanaika S. Hok-A-Hin, Allerdien Visser, Wiesje M. van der Flier, Frederik Barkhof, Marta del Campo, Martijn C. Schut, Alexandre Bejanin, Daniel Alcolea, Charlotte E. Teunissen, Lisa Vermunt

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Investigating the relationship between thalamic iron concentration and disease severity in secondary progressive multiple sclerosis using quantitative susceptibility mapping: Cross... by Thomas Williams, Nevin John, Alberto Calvi, Alessia Bianchi, Floriana De Angelis, Anisha Doshi, Sarah Wright, Madiha Shatila, Marios C. Yiannakas, Fatima Chowdhury, Jon Stutters, Antonio Ricciardi, Ferran Prados, David MacManus, Francesco Grussu, Anita Karsa, Becky Samson, Marco Battiston, Claudia A.M. Gandini Wheeler-Kingshott, Karin Shmueli, Olga Ciccarelli, Frederik Barkhof, Jeremy Chataway, Jeremy Chataway, Thomas Williams, Nevin John, Floriana De Angelis, Alberto Calvi, Alessia Bianchi, Sarah Wright, Madiha Shatila, Anisha Doshi, Wallace Brownlee, Claudia AM. Gandini Wheeler-Kingshott, Frederik Barkhof, Olga Ciccarelli, Jonathan Stutters, Ferran Prados Carrasco, Antonio Ricciardi, Marios Yiannakas, David MacManus, Megan Wynne, Marie Braisher, James Blackstone, Leanne Hockey, Josephine Parker, Jennifer Flight, Chris Frost, Jennifer Nicholas, Stuart Nixon, Judy Beveridge

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Enabling new insights from old scans by repurposing clinical MRI archives for multiple sclerosis research by Philipp Goebl, Jed Wingrove, Omar Abdelmannan, Barbara Brito Vega, Jonathan Stutters, Silvia Da Graca Ramos, Owain Kenway, Thomas Rossor, Evangeline Wassmer, Douglas L. Arnold, D. Louis Collins, Cheryl Hemingway, Sridar Narayanan, Jeremy Chataway, Declan Chard, Juan Eugenio Iglesias, Frederik Barkhof, Geoff J. M. Parker, Neil P. Oxtoby, Yael Hacohen, Alan Thompson, Daniel C. Alexander, Olga Ciccarelli, Arman Eshaghi

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The effect of aerobic exercise on cerebral perfusion in patients with vascular cognitive impairment, the Excersion-VCI randomised controlled clinical trial by Liz R. van Hout, Justine Moonen, Annebet E. Leeuwis, Juliette van Alphen, Mathijs Dijsselhof, Raquel P. Amier, Frederik Barkhof, Esther E. Bron, Doeschka A. Ferro, Alexander G.J. Harms, Rosalie J. Huijsmans, Joost P.A. Kuijer, Sanne Kuipers, Matthias J.P. van Osch, Niels D. Prins, Marc B. Rietberg, Charlotte E. Teunissen, Henk Jan Mutsaerts, Geert Jan Biessels, Wiesje M. van der Flier

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A large-scale multi-centre study characterising atrophy heterogeneity in Alzheimer’s disease by Vikram Venkatraghavan, Damiano Archetti, Pierrick Bourgeat, Chenyang Jiang, Mara ten Kate, Anna C. van Loenhoud, Rik Ossenkoppele, Charlotte E. Teunissen, Elsmarieke van de Giessen, Yolande A.L. Pijnenburg, Giovanni B. Frisoni, Béla Weiss, Zoltán Vidnyánszky, Tibor Auer, Stanley Durrleman, Alberto Redolfi, Simon M. Laws, Paul Maruff, Neil P. Oxtoby, Andre Altmann, Daniel C. Alexander, Wiesje M. van der Flier, Frederik Barkhof, Betty M. Tijms

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Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol... by Catherine Morgan, Frederik Barkhof, David L Thomas, Saima Hilal, Moritz Brandt, Betty M Tijms, Majon Muller, Tormod Fladby, Jennifer Linn, Per Selnes, Atle Bjørnerud, Elsmarieke M van de Giessen, Beatriz Padrela, Amnah Mahroo, Mervin Tee, Markus H Sneve, Paulien Moyaert, Oliver Geier, Joost P A Kuijer, Soetkin Beun, Wibeke Nordhøy, Yufei David Zhu, Mareike A Buck, Daniel C Hoinkiss, Simon Konstandin, Jörn Huber, Julia Wiersinga, Roos Rikken, Diederick de Leeuw, Håkon Grydeland, Lynette Tippett, Erin E Cawston, Esin Ozturk-Isik, Anders Fjell, Kristine Walhovd, Lene Pålhaugen, Patricia Clement, Eric Achten, Udunna Anazodo, Klaus Eickel, Jan Petr, Matthias Günther, Henk J M M Mutsaerts

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