Antibody-antigen-adjuvant conjugates enable co-delivery of antigen and adjuvant to dendritic cells in cis but only have partial targeting specificity. by Martin Kreutz, Benoit Giquel, Qin Hu, Ram Abuknesha, Satoshi Uematsu, Shizuo Akira, Frank O Nestle, Sandra S Diebold

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A systems model for immune cell interactions unravels the mechanism of inflammation in human skin. by Najl V Valeyev, Christian Hundhausen, Yoshinori Umezawa, Nikolay V Kotov, Nikolay V Kotov, Gareth Williams, Alex Clop, Crysanthi Ainali, Christos Ouzounis, Sophia Tsoka, Frank O Nestle

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Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery. by Federica Villanova, Paola Di Meglio, Margaret Inokuma, Nima Aghaeepour, Esperanza Perucha, Jennifer Mollon, Laurel Nomura, Maria Hernandez-Fuentes, Andrew Cope, A Toby Prevost, Susanne Heck, Vernon Maino, Graham Lord, Ryan R Brinkman, Frank O Nestle

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An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element. by Alex Clop, Anna Bertoni, Sarah L Spain, Michael A Simpson, Venu Pullabhatla, Raul Tonda, Christian Hundhausen, Paola Di Meglio, Pieter De Jong, Adrian C Hayday, Frank O Nestle, Jonathan N Barker, Robert J A Bell, Francesca Capon, Richard C Trembath

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Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies. by Amy E Gilbert, Panagiotis Karagiannis, Tihomir Dodev, Alexander Koers, Katie Lacy, Debra H Josephs, Pooja Takhar, Jenny L C Geh, Ciaran Healy, Mark Harries, Katharine M Acland, Sarah M Rudman, Rebecca L Beavil, Philip J Blower, Andrew J Beavil, Hannah J Gould, James Spicer, Frank O Nestle, Sophia N Karagiannis

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The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. by Alexandra C Nica, Leopold Parts, Daniel Glass, James Nisbet, Amy Barrett, Magdalena Sekowska, Mary Travers, Simon Potter, Elin Grundberg, Kerrin Small, Asa K Hedman, Veronique Bataille, Jordana Tzenova Bell, Gabriela Surdulescu, Antigone S Dimas, Catherine Ingle, Frank O Nestle, Paola di Meglio, Josine L Min, Alicja Wilk, Christopher J Hammond, Neelam Hassanali, Tsun-Po Yang, Stephen B Montgomery, Steve O'Rahilly, Cecilia M Lindgren, Krina T Zondervan, Nicole Soranzo, Inês Barroso, Richard Durbin, Kourosh Ahmadi, Panos Deloukas, Mark I McCarthy, Emmanouil T Dermitzakis, Timothy D Spector, MuTHER Consortium

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